E-cadherin expression is correlated with focal adhesion kinase inhibitor resistance in Merlin-negative malignant mesothelioma cells

Modeling mesothelioma utilizing human mesothelial cells reveals involvement of phospholipase-C beta 4 in YAP-active mesothelioma cell proliferation

(2016) Tatsuo Kakiuchi et al.   CARCINOGENESIS

Focal Adhesion Kinase Regulates the DNA Damage Response and Its Inhibition Radiosensitizes Mutant KRAS Lung Cancer

(2016) K.-J. Tang et al.   CLINICAL CANCER RESEARCH

Oncogenic Receptor Tyrosine Kinases Directly Phosphorylate Focal Adhesion Kinase (FAK) as a Resistance Mechanism to FAK-Kinase Inhibitors

(2016) Timothy A. Marlowe et al.   MOLECULAR CANCER THERAPEUTICS

Comprehensive genomic analysis of malignant pleural mesothelioma identifies recurrent mutations, gene fusions and splicing alterations

(2016) Raphael Bueno et al.   NATURE GENETICS

Targeting focal adhesion kinase renders pancreatic cancers responsive to checkpoint immunotherapy

(2016) Hong Jiang et al.   NATURE MEDICINE

Whole-Exome Sequencing Reveals Frequent Genetic Alterations in BAP1, NF2, CDKN2A, and CUL1 in Malignant Pleural Mesothelioma

(2014) G. Guo et al.   CANCER RESEARCH

Analyses of merlin/NF2 connection to FAK inhibitor responsiveness in serous ovarian cancer

(2014) Nina R. Shah et al.   GYNECOLOGIC ONCOLOGY

The Global Spread of Asbestos

(2014) Arthur L. Frank et al.   Annals of Global Health

E-cadherin-integrin crosstalk in cancer invasion and metastasis

(2013) M. Canel et al.   JOURNAL OF CELL SCIENCE

Nuclear FAK: a new mode of gene regulation from cellular adhesions

(2013) Ssang-Taek Steve Lim   MOLECULES AND CELLS

LIM-domain protein AJUBA suppresses malignant mesothelioma cell proliferation via Hippo signaling cascade

(2013) I Tanaka et al.   ONCOGENE

E-cadherin promotes proliferation of human ovarian cancer cells in vitro via activating MEK/ERK pathway

(2012) Ling-ling Dong et al.   ACTA PHARMACOLOGICA SINICA

Investigation of the freely available easy-to-use software ‘EZR’ for medical statistics

(2012) Y Kanda   BONE MARROW TRANSPLANTATION

Merlin: a tumour suppressor with functions at the cell cortex and in the nucleus

(2012) Wei Li et al.   EMBO REPORTS

Activated Leukocyte Cell-Adhesion Molecule (ALCAM) Promotes Malignant Phenotypes of Malignant Mesothelioma

(2012) Futoshi Ishiguro et al.   Journal of Thoracic Oncology

YAP induces malignant mesothelioma cell proliferation by upregulating transcription of cell cycle-promoting genes

(2012) T Mizuno et al.   ONCOGENE

LATS2 Is a Tumor Suppressor Gene of Malignant Mesothelioma

(2011) H. Murakami et al.   CANCER RESEARCH

PND-1186 FAK inhibitor selectively promotes tumor cell apoptosis in three-dimensional environments

(2010) Isabelle Tanjoni et al.   CANCER BIOLOGY & THERAPY

Merlin, a “Magic” Linker Between the Extracellular Cues and Intracellular Signaling Pathways that Regulate Cell Motility, Proliferation, and Survival

(2010) Ivan Stamenkovic et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

The NF2 Tumor Suppressor, Merlin, Regulates Epidermal Development through the Establishment of a Junctional Polarity Complex

(2010) Andrew B. Gladden et al.   DEVELOPMENTAL CELL

Mammary Epithelial-Specific Ablation of the Focal Adhesion Kinase Suppresses Mammary Tumorigenesis by Affecting Mammary Cancer Stem/Progenitor Cells

(2009) M. Luo et al.   CANCER RESEARCH

Genomic abnormalities and signal transduction dysregulation in malignant mesothelioma cells

(2009) Yoshitaka Sekido   CANCER SCIENCE

Combined inhibition of MET and EGFR suppresses proliferation of malignant mesothelioma cells

(2009) Koji Kawaguchi et al.   CARCINOGENESIS

Tumor-suppression functions of merlin are independent of its role as an organizer of the actin cytoskeleton in Schwann cells

(2009) D. Lallemand et al.   JOURNAL OF CELL SCIENCE

Loss of the Tumor Suppressor Gene NF2, Encoding Merlin, Constitutively Activates Integrin-Dependent mTORC1 Signaling

(2009) M. A. Lopez-Lago et al.   MOLECULAR AND CELLULAR BIOLOGY

NF2/Merlin Is a Novel Negative Regulator of mTOR Complex 1, and Activation of mTORC1 Is Associated with Meningioma and Schwannoma Growth

(2009) M. F. James et al.   MOLECULAR AND CELLULAR BIOLOGY

Regulation of cell–cell adhesion by the cadherin–catenin complex

(2008) W. James Nelson   BIOCHEMICAL SOCIETY TRANSACTIONS

Loss of E-Cadherin Promotes Ovarian Cancer Metastasis via  5-Integrin, which Is a Therapeutic Target

(2008) K. Sawada et al.   CANCER RESEARCH

The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells

(2008) Sendurai A. Mani et al.   CELL

Problems in mesothelioma diagnosis

(2008) Bruce Addis et al.   HISTOPATHOLOGY

The Neurofibromatosis 2 Protein, Merlin, Regulates Glial Cell Growth in an ErbB2- and Src-Dependent Manner

(2008) S. S. Houshmandi et al.   MOLECULAR AND CELLULAR BIOLOGY