NLRP1 promotes tumor growth by enhancing inflammasome activation and suppressing apoptosis in metastatic melanoma

Germline NLRP1 Mutations Cause Skin Inflammatory and Cancer Susceptibility Syndromes via Inflammasome Activation

(2016) Franklin L. Zhong et al.   CELL

The NLRP1 inflammasomes

(2015) Joseph Chavarría-Smith et al.   IMMUNOLOGICAL REVIEWS

Cross Talk between Neuroregulatory Molecule and Monocyte: Nerve Growth Factor Activates the Inflammasome

(2015) Ananya Datta-Mitra et al.   PLoS One

THP-1 cell line: An in vitro cell model for immune modulation approach

(2014) Wasaporn Chanput et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Cancer-related inflammation and treatment effectiveness

(2014) Connie I Diakos et al.   LANCET ONCOLOGY

Tumor-Derived Interleukin-1 Promotes Lymphangiogenesis and Lymph Node Metastasis through M2-Type Macrophages

(2014) Kosuke Watari et al.   PLoS One

Aberrant Expression of Interleukin-1β and Inflammasome Activation in Human Malignant Gliomas

(2014) Leonid Tarassishin et al.   PLoS One

Inflammasomes in cancer: a double-edged sword

(2014) Ryan Kolb et al.   Protein & Cell

Nod-Like Receptors: Key Molecular Switches in the Conundrum of Cancer

(2014) Andrew Kent et al.   Frontiers in Immunology

Transcriptome Profiling Identifies HMGA2 as a Biomarker of Melanoma Progression and Prognosis

(2013) Leon Raskin et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Nod-Like Receptor Protein 1 Inflammasome Mediates Neuron Injury under High Glucose

(2013) Xian-Fang Meng et al.   MOLECULAR NEUROBIOLOGY

Thymoquinone suppresses metastasis of melanoma cells by inhibition of NLRP3 inflammasome

(2013) Israr Ahmad et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

NLRP3 Suppresses NK Cell-Mediated Responses to Carcinogen-Induced Tumors and Metastases

(2012) M. T. Chow et al.   CANCER RESEARCH

Dual Role of Apoptosis-Associated Speck-Like Protein Containing a CARD (ASC) in Tumorigenesis of Human Melanoma

(2012) Weimin Liu et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

NF-κB is activated in response to temozolomide in an AKT-dependent manner and confers protection against the growth suppressive effect of the drug

(2012) Simona Caporali et al.   Journal of Translational Medicine

Anthrax Lethal Factor Cleavage of Nlrp1 Is Required for Activation of the Inflammasome

(2012) Jonathan L. Levinsohn et al.   PLoS Pathogens

Chronic Inflammation in Cancer Development

(2012) Gabriele Multhoff et al.   Frontiers in Immunology

The Inflammasome NLRs in Immunity, Inflammation, and Associated Diseases

(2011) Beckley K. Davis et al.   Annual Review of Immunology

Computer-based fluorescence quantification: a novel approach to study nucleolar biology

(2011) Mohamed Kodiha et al.   BMC CELL BIOLOGY

Inflammasomes as molecular mediators of inflammation and cancer: Potential role in melanoma

(2011) Jeffrey H. Dunn et al.   CANCER LETTERS

Inflammation-mediated promotion of invasion and metastasis

(2010) Graziella Solinas et al.   CANCER AND METASTASIS REVIEWS

DNA Topoisomerases and Their Poisoning by Anticancer and Antibacterial Drugs

(2010) Yves Pommier et al.   CHEMISTRY & BIOLOGY

Integrative Genome Comparison of Primary and Metastatic Melanomas

(2010) Omar Kabbarah et al.   PLoS One

Susceptibility to Anthrax Lethal Toxin-Induced Rat Death Is Controlled by a Single Chromosome 10 Locus That Includes rNlrp1

(2010) Zachary L. Newman et al.   PLoS Pathogens

Constitutively Active Inflammasome in Human Melanoma Cells Mediating Autoinflammation via Caspase-1 Processing and Secretion of Interleukin-1β

(2009) Miyako Okamoto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Induced expression of death domain genes NALP1 and NALP5 following neuronal injury

(2008) C. Frederick Lo et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The gene expression profiles of primary and metastatic melanoma yields a transition point of tumor progression and metastasis

(2008) Adam I Riker et al.   BMC Medical Genomics

A role for caspase 2 and PIDD in the process of p53-mediated apoptosis

(2008) N. Baptiste-Okoh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA