Germline NLRP1 Mutations Cause Skin Inflammatory and Cancer Susceptibility Syndromes via Inflammasome Activation

Published 2016 View Full Article

Authors

Keywords

inflammasome, NLRP1, skin inflammation, keratosis lichenoides chronica, multiple self-healing squamous cell carcinoma, MSPC, MSSE, gain-of-function, cancer, germline, genodermatosis, IL-1, ASC, keratinocytes

Journal

CELL

Volume 167, Issue 1, Pages 187-202.e17

Publisher

Elsevier BV

Online

2016-09-23

DOI

10.1016/j.cell.2016.09.001

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