Loss of RhoA promotes skin tumor formation and invasion by upregulation of RhoB

Activating mutations in genes related to TCR signaling in angioimmunoblastic and other follicular helper T-cell-derived lymphomas

(2016) D. Vallois et al.   BLOOD

LC3/GABARAP family proteins: autophagy-(un)related functions

(2016) Marco B. E. Schaaf et al.   FASEB JOURNAL

Variegated RHOA mutations in adult T-cell leukemia/lymphoma

(2015) Y. Nagata et al.   BLOOD

Genomic landscape of carcinogen-induced and genetically induced mouse skin squamous cell carcinoma

(2015) Dany Nassar et al.   NATURE MEDICINE

Simultaneous Irradiation of Fibroblasts and Carcinoma Cells Repress the Secretion of Soluble Factors Able to Stimulate Carcinoma Cell Migration

(2015) Adnan Arshad et al.   PLoS One

RhoA determines disease progression by controlling neutrophil motility and restricting hyperresponsiveness

(2014) R. T. Jennings et al.   BLOOD

Discovery and saturation analysis of cancer genes across 21 tumour types

(2014) Michael S. Lawrence et al.   NATURE

Recurrent gain-of-function mutations of RHOA in diffuse-type gastric carcinoma

(2014) Miwako Kakiuchi et al.   NATURE GENETICS

A recurrent inactivating mutation in RHOA GTPase in angioimmunoblastic T cell lymphoma

(2014) Hae Yong Yoo et al.   NATURE GENETICS

Somatic RHOA mutation in angioimmunoblastic T cell lymphoma

(2014) Mamiko Sakata-Yanagimoto et al.   NATURE GENETICS

Recurrent mutations in epigenetic regulators, RHOA and FYN kinase in peripheral T cell lymphomas

(2014) Teresa Palomero et al.   NATURE GENETICS

RHOA inactivation enhances Wnt signalling and promotes colorectal cancer

(2014) Paulo Rodrigues et al.   Nature Communications

The effect of Rho kinase inhibition on long-term keratinocyte proliferation is rapid and conditional

(2014) Sandra Chapman et al.   Stem Cell Research & Therapy

RhoB Promotes Cancer Initiation by Protecting Keratinocytes from UVB-Induced Apoptosis but Limits Tumor Aggressiveness

(2013) Nicolas Meyer et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

GTPase switch: Ras then Rho and Rac

(2013) Anne Ridley   NATURE CELL BIOLOGY

Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal

(2013) J. Gao et al.   Science Signaling

Rho-associated kinases in tumorigenesis: re-considering ROCK inhibition for cancer therapy

(2012) Nicola Rath et al.   EMBO REPORTS

Rho GTPase function in development: How in vivo models change our view

(2012) Esben Pedersen et al.   EXPERIMENTAL CELL RESEARCH

RhoB regulates uPAR signalling

(2012) D. Alfano et al.   JOURNAL OF CELL SCIENCE

The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.

(2012) Ethan Cerami et al.   Cancer Discovery

RhoB regulates cell migration through altered focal adhesion dynamics

(2012) F. M. Vega et al.   Open Biology

Actomyosin-Mediated Cellular Tension Drives Increased Tissue Stiffness and β-Catenin Activation to Induce Epidermal Hyperplasia and Tumor Growth

(2011) Michael S. Samuel et al.   CANCER CELL

RhoA and RhoC have distinct roles in migration and invasion by acting through different targets

(2011) Francisco M. Vega et al.   JOURNAL OF CELL BIOLOGY

RhoA is dispensable for skin development, but crucial for contraction and directed migration of keratinocytes

(2011) Ben Jackson et al.   MOLECULAR BIOLOGY OF THE CELL

Tumor-initiating stem cells of squamous cell carcinomas and their control by TGF-  and integrin/focal adhesion kinase (FAK) signaling

(2011) M. Schober et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of Rho GTPase crosstalk, degradation and activity by RhoGDI1

(2010) Etienne Boulter et al.   NATURE CELL BIOLOGY

Assaying proliferation and differentiation capacity of stem cells using disaggregated adult mouse epidermis

(2010) Kim B Jensen et al.   Nature Protocols

Rac1 is crucial for Ras-dependent skin tumor formation by controlling Pak1-Mek-Erk hyperactivation and hyperproliferation in vivo

(2010) Z Wang et al.   ONCOGENE

Histone H3K27 methyltransferase Ezh2 represses Wnt genes to facilitate adipogenesis

(2010) L. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Determinants Allowing Endolysosomal Sorting and Degradation of Endosomal GTPases

(2010) Ruth A. Valero et al.   TRAFFIC

The C-Terminal Sequence of RhoB Directs Protein Degradation through an Endo-Lysosomal Pathway

(2009) Dolores Pérez-Sala et al.   PLoS One

Rho Family GTPase Modification and Dependence on CAAXMotif-signaled Posttranslational Modification

(2008) Patrick J. Roberts et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

RhoA-GDP Regulates RhoB Protein Stability

(2008) T. T. Giang Ho et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crosstalk between small GTPases and polarity proteins in cell polarization

(2008) Sandra Iden et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY