A muscle-specific protein ‘myoferlin’ modulates IL-6/STAT3 signaling by chaperoning activated STAT3 to nucleus

High expression of myoferlin is associated with poor outcome in oropharyngeal squamous cell carcinoma patients and is inversely associated with HPV-status

(2016) Bhavna Kumar et al.   Oncotarget

Identification of Differentially Expressed Proteins of Normal and Cancerous Human Colorectal Tissues by Liquid Chromatograph-Mass Spectrometer Based on iTRAQ Approach

(2015) Jingjing Lv et al.   CANCER INVESTIGATION

Decreased expression and prognostic role of EHD2 in human breast carcinoma: correlation with E-cadherin

(2015) Yuhua Shi et al.   JOURNAL OF MOLECULAR HISTOLOGY

Role of EHD2 in migration and invasion of human breast cancer cells

(2015) Xiaojing Yang et al.   TUMOR BIOLOGY

The role of intratumoral and systemic IL-6 in breast cancer

(2013) Christine Dethlefsen et al.   BREAST CANCER RESEARCH AND TREATMENT

Myoferlin Is a Key Regulator of EGFR Activity in Breast Cancer

(2013) A. Turtoi et al.   CANCER RESEARCH

Effects of EHD2 interference on migration of esophageal squamous cell carcinoma

(2013) Mei Li et al.   MEDICAL ONCOLOGY

Myoferlin Depletion in Breast Cancer Cells Promotes Mesenchymal to Epithelial Shape Change and Stalls Invasion

(2012) Ruth Li et al.   PLoS One

Stat3/Socs3 Activation by IL-6 Transsignaling Promotes Progression of Pancreatic Intraepithelial Neoplasia and Development of Pancreatic Cancer

(2011) Marina Lesina et al.   CANCER CELL

Identification of Novel Accessible Proteins Bearing Diagnostic and Therapeutic Potential in Human Pancreatic Ductal Adenocarcinoma

(2011) Andrei Turtoi et al.   JOURNAL OF PROTEOME RESEARCH

IL-6 Promotes Head and Neck Tumor Metastasis by Inducing Epithelial-Mesenchymal Transition via the JAK-STAT3-SNAIL Signaling Pathway

(2011) A. Yadav et al.   MOLECULAR CANCER RESEARCH

Stem cell marker (Nanog) and Stat-3 signaling promote MicroRNA-21 expression and chemoresistance in hyaluronan/CD44-activated head and neck squamous cell carcinoma cells

(2011) L Y W Bourguignon et al.   ONCOGENE

Mechanistic modeling of the effects of myoferlin on tumor cell invasion

(2011) M. C. Eisenberg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Myoferlin gene silencing decreases Tie-2 expression in vitro and angiogenesis in vivo

(2011) Carol Yu et al.   VASCULAR PHARMACOLOGY

STAT3 is essential for the maintenance of neurosphere-initiating tumor cells in patients with glioblastomas: A potential for targeted therapy?

(2010) Claire Villalva et al.   INTERNATIONAL JOURNAL OF CANCER

IL-6 promotes malignant growth of skin SCCs by regulating a network of autocrine and paracrine cytokines

(2010) Wiltrud Lederle et al.   INTERNATIONAL JOURNAL OF CANCER

Myoferlin regulation by NFAT in muscle injury, regeneration and repair

(2010) A. R. Demonbreun et al.   JOURNAL OF CELL SCIENCE

The Nuclear Pore Complex and Nuclear Transport

(2010) S. R. Wente et al.   Cold Spring Harbor Perspectives in Biology

Myoferlin is critical for endocytosis in endothelial cells

(2009) Pascal N. Bernatchez et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Interleukin-6 predicts recurrence and survival among head and neck cancer patients

(2008) Sonia A. Duffy et al.   CANCER

The Endocytic Recycling Protein EHD2 Interacts with Myoferlin to Regulate Myoblast Fusion

(2008) Katherine R. Doherty et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Endothelial cells expressing Bcl-2 promotes tumor metastasis by enhancing tumor angiogenesis, blood vessel leakiness and tumor invasion

(2008) Pawan Kumar et al.   LABORATORY INVESTIGATION

Lymph node mapping in the mouse

(2007) Maria I. Harrell et al.   JOURNAL OF IMMUNOLOGICAL METHODS