Isoprenylcysteine carboxylmethyltransferase is critical for malignant transformation and tumor maintenance by all RAS isoforms
Published 2017 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Isoprenylcysteine carboxylmethyltransferase is critical for malignant transformation and tumor maintenance by all RAS isoforms
Authors
Keywords
-
Journal
ONCOGENE
Volume 36, Issue 27, Pages 3934-3942
Publisher
Springer Nature
Online
2017-02-14
DOI
10.1038/onc.2016.508
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Inhibition of isoprenylcysteine carboxylmethyltransferase augments BCR-ABL1 tyrosine kinase inhibition-induced apoptosis in chronic myeloid leukemia
- (2016) Wen Tian Sun et al. EXPERIMENTAL HEMATOLOGY
- Protein prenylation: unique fats make their mark on biology
- (2016) Mei Wang et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Allele-specific inhibitors inactivate mutant KRAS G12C by a trapping mechanism
- (2016) P. Lito et al. SCIENCE
- Targeting RAS Membrane Association: Back to the Future for Anti-RAS Drug Discovery?
- (2015) A. D. Cox et al. CLINICAL CANCER RESEARCH
- K-Ras4A splice variant is widely expressed in cancer and uses a hybrid membrane-targeting motif
- (2015) Frederick D. Tsai et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- High-throughput genotyping of CRISPR/Cas9-mediated mutants using fluorescent PCR-capillary gel electrophoresis
- (2015) Muhammad Khairul Ramlee et al. Scientific Reports
- An improved isoprenylcysteine carboxylmethyltransferase inhibitor induces cancer cell death and attenuates tumor growth in vivo
- (2014) Hiu Yeung Lau et al. CANCER BIOLOGY & THERAPY
- Dragging Ras Back in the Ring
- (2014) Andrew G. Stephen et al. CANCER CELL
- Isoprenylcysteine carboxylmethyltransferase regulates mitochondrial respiration and cancer cell metabolism
- (2014) J T Teh et al. ONCOGENE
- Isoprenylcysteine carboxylmethyltransferase deficiency exacerbates KRAS-driven pancreatic neoplasia via Notch suppression
- (2013) Helen Court et al. JOURNAL OF CLINICAL INVESTIGATION
- K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions
- (2013) Jonathan M. Ostrem et al. NATURE
- Genome engineering using the CRISPR-Cas9 system
- (2013) F Ann Ran et al. Nature Protocols
- Targeting Isoprenylcysteine Methylation Ameliorates Disease in a Mouse Model of Progeria
- (2013) M. X. Ibrahim et al. SCIENCE
- A Comprehensive Survey of Ras Mutations in Cancer
- (2012) I. A. Prior et al. CANCER RESEARCH
- Rare Codons Regulate KRas Oncogenesis
- (2012) Benjamin L. Lampson et al. CURRENT BIOLOGY
- Intersection of FOXO- and RUNX1-mediated gene expression programs in single breast epithelial cells during morphogenesis and tumor progression
- (2011) L. Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Ras trafficking, localization and compartmentalized signalling
- (2011) Ian A. Prior et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Inhibition of isoprenylcysteine carboxylmethyltransferase induces autophagic-dependent apoptosis and impairs tumor growth
- (2010) M Wang et al. ONCOGENE
- The Posttranslational Processing of Prelamin A and Disease
- (2009) Brandon S.J. Davies et al. Annual Review of Genomics and Human Genetics
- Topology of Mammalian Isoprenylcysteine Carboxyl Methyltransferase Determined in Live Cells with a Fluorescent Probe
- (2009) L. P. Wright et al. MOLECULAR AND CELLULAR BIOLOGY
- Inactivating Icmt ameliorates K-RAS-induced myeloproliferative disease
- (2008) A. M. Wahlstrom et al. BLOOD
- A Small Molecule Inhibitor of Isoprenylcysteine Carboxymethyltransferase Induces Autophagic Cell Death in PC3 Prostate Cancer Cells
- (2008) Mei Wang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
Become a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get StartedAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started