Article
Agriculture, Dairy & Animal Science
Pradeep Krishna Javvaji, Arindam Dhali, Joseph Rabinson Francis, Atul P. Kolte, Sudhir C. Roy, Sellappan Selvaraju, Anjumoni Mech, Veerasamy Sejian
Summary: The study showed that IGF-1 treatment significantly improved the developmental competence of ovine oocytes, enhancing the maturation rate and embryo development. This effect was achieved through the regulation of the PI3K/Akt and apoptosis signaling pathways.
ANIMAL BIOTECHNOLOGY
(2021)
Article
Agriculture, Dairy & Animal Science
Juan P. Cabeza, Juan Camera, Olinda Briski, Minerva Yauri Felipe, Daniel F. Salamone, Andres Gambini
Summary: This study investigates the use of a novel zinc chelator for activating bovine and porcine oocytes. The results show that the zinc chelator can successfully induce blastocyst development in both species, although developmental rates and embryo quality are compromised in bovine compared to calcium-induced embryos. On the contrary, the new concentration and incubation time of the zinc chelator improve developmental rates in porcine without affecting embryo quality. These findings contribute to understanding the role of zinc in oocyte activation and preimplantation embryo development across different mammalian species.
Review
Environmental Sciences
Juanmei Gao, Wanhua Shen
Summary: The Xenopus model is advantageous for studying embryo development and developmental toxicity, as well as human diseases. It has been successfully used to study various diseases, including fetal alcohol spectrum disorders, autism, epilepsy, and cardiovascular disease. Xenopus also has potential applications in genetic and chemical screening.
ENVIRONMENTAL POLLUTION
(2021)
Review
Biochemistry & Molecular Biology
Pawel Kordowitzki, Gabriela Sokolowska, Marta Wasielak-Politowska, Agnieszka Skowronska, Mariusz T. Skowronski
Summary: The oocyte plays a crucial role in embryo development, with cell-to-cell and cell-to-matrix communications being key for oocyte's developmental competence. Pannexins and Connexins are families of channels that are important for various physiological and pathological processes related to oocyte development and fertility.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Developmental Biology
Rowena Smith, Andrej Susor, Hao Ming, Janet Tait, Marco Conti, Zongliang Jiang, Chih-Jen Lin
Summary: Oocyte developmental competence and embryogenesis rely on the H3.3 chaperone Hira complex, which regulates chromatin condensation and transcriptional quiescence.
Article
Endocrinology & Metabolism
Dongmei Deng, Juan Xie, Yin Tian, Ling Zhu, Xuemei Liu, Junxia Liu, Guoning Huang, Jingyu Li
Summary: Acquisition of germinal vesicle (GV) stage oocytes for fertility preservation (FP) offers several benefits over in vivo matured oocyte cryopreservation following ovarian stimulation. Two approaches for GV oocytes are available: vitrification before in vitro maturation (IVM) at the GV stage or post-IVM at the metaphase II (MII) stage. This study found that oocyte vitrification at the MII stage after IVM is more suitable for patients who require immediate FP.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Cell Biology
Mingrui Li, Chao Ren, Shuai Zhou, Yuanlin He, Yueshuai Guo, Hao Zhang, Lu Liu, Qiqi Cao, Congjing Wang, Jie Huang, Yue Hu, Xue Bai, Xuejiang Guo, Wenjie Shu, Ran Huo
Summary: The study found that abnormal expression of splicing regulation proteins in aged oocytes affects the splicing of DNA repair-related genes in 2-cell embryos, reducing their developmental potential.
Article
Biotechnology & Applied Microbiology
Erin Chille, Emma Strand, Mayaan Neder, Valeria Schmidt, Madeleine Sherman, Tali Mass, Hollie Putnam
Summary: In the Pacific rice coral, four expression peaks were identified, representing maternal complement, two waves of the MZT, and adult expression. Maternal transcripts are dominated by functions related to cell division, methylation, biosynthesis, metabolism, and protein/RNA processing and transport. The two waves of the MZT involve functions related to biosynthesis, cell division, transcription, ion/peptide transport, and cell signaling. Adult expression is enriched for functions related to signaling, metabolism, and ion/peptide transport.
Article
Agriculture, Dairy & Animal Science
Elisa Serra, Sergio Domenico Gadau, Giovanni Giuseppe Leoni, Salvatore Naitana, Sara Succu
Summary: The study found that oocytes collected in spring from prepubertal ewes have higher developmental competence and vitality in in vitro embryo production, with lower production of reactive oxygen species. The research indicates that the season of collection can affect the developmental competence, energetic status, and tubulin assessment of oocytes, emphasizing the importance of considering the season when collecting prepubertal ovine oocytes for in vitro embryo reproduction programs.
Article
Biochemistry & Molecular Biology
Udayanga Sanath Kankanam Gamage, Shu Hashimoto, Yuki Miyamoto, Tatsuya Nakano, Masaya Yamanaka, Akiko Koike, Manabu Satoh, Yoshiharu Morimoto
Summary: This study investigates the supplementation of autologous adipose stem cell mitochondria in vitrified and warmed oocytes and finds that this supplementation can restore damaged mitochondrial quality and enhance embryo developmental capacity.
Article
Reproductive Biology
Amirhossein Abazarikia, Mahdi Zhandi, Armin Towhidi, Malak Shakeri, Ali Reza Youse, Amir Aliyan
Summary: The study showed that introducing conjugated linoleic acid (CLA) can improve oocyte developmental competence, reduce aberrant spindle organization of heat-stressed oocytes, and does not cause epigenetic alteration in the obtained blastocysts.
Article
Obstetrics & Gynecology
A. Cardona Barberan, D. Bonte, A. Boel, V Thys, R. Paredis, F. Machtelinckx, P. De Sutter, I De Croo, L. Leybaert, D. Stoop, P. Coucke, F. Vanden Meerschaut, B. Heindryckx
Summary: The study aimed to investigate whether assisted oocyte activation (AOA) could overcome recurrent embryo developmental problems after ICSI. The results showed that AOA did not improve blastocyst formation in patients with recurrent embryo developmental problems after ICSI.
HUMAN REPRODUCTION
(2023)
Review
Genetics & Heredity
Luoyu Mo, Jun Ma, Yan Xiong, Xianrong Xiong, Daoliang Lan, Jian Li, Shi Yin
Summary: This review summarizes the factors affecting the in vitro maturation and developmental ability of yak oocytes in recent years, providing a theoretical basis for in vitro fertilization and embryo production in yaks.
Article
Developmental Biology
Zvi Roth
Summary: High temperatures can affect follicles and oocytes, leading to impaired follicle development and compromised competence of oocytes to develop into embryos. Studies have shown various mechanisms of oocyte damage due to heat stress, with only subpopulations of follicles affected rather than the entire ovarian reserve.
REPRODUCTION FERTILITY AND DEVELOPMENT
(2021)
Review
Veterinary Sciences
Miguel A. Velazquez
Summary: The nutritional status of oocyte donors plays a significant role in the efficiency of in vitro embryo production (IVEP) in cattle. Moderate body condition score and supply of maintenance nutritional requirements seem to be enough to provide bovine oocyte donors with a good chance of producing embryos in vitro.
VETERINARY SCIENCES
(2023)