Pharmacological effects of protocatechuic acid and its therapeutic potential in neurodegenerative diseases: Review on the basis of in vitro and in vivo studies in rodents and humans

Anti-α-synuclein immunotherapy reduces α-synuclein propagation in the axon and degeneration in a combined viral vector and transgenic model of synucleinopathy

(2017) Brian Spencer et al.   Acta Neuropathologica Communications

Protocatechuic acid inhibits osteoclast differentiation and stimulates apoptosis in mature osteoclasts

(2016) Yi-Xin Wu et al.   BIOMEDICINE & PHARMACOTHERAPY

Protocatechuic Acid: Inhibition of Fibril Formation, Destabilization of Preformed Fibrils of Amyloid-β and α-Synuclein, and Neuroprotection

(2016) Ruth Hornedo-Ortega et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Inflammation, Antiinflammatory Agents, and Alzheimer’s Disease: The Last 22 Years

(2016) Patrick L. McGeer et al.   JOURNAL OF ALZHEIMERS DISEASE

Attenuation of acute restraint stress-induced depressive like behavior and hippocampal alterations with protocatechuic acid treatment in mice

(2016) Vishnu N. Thakare et al.   METABOLIC BRAIN DISEASE

Cyanidin-3-O-glucoside: Physical-Chemistry, Foodomics and Health Effects

(2016) Francisco Olivas-Aguirre et al.   MOLECULES

Oxidative stress, mitochondrial dysfunction and neurodegenerative diseases; a mechanistic insight

(2015) Aashiq Hussain Bhat et al.   BIOMEDICINE & PHARMACOTHERAPY

Pharmacological Properties of Protocatechuic Acid and Its Potential Roles as Complementary Medicine

(2015) Yoswaris Semaming et al.   Evidence-based Complementary and Alternative Medicine

Examining the neuroprotective effects of protocatechuic acid and chrysin on in vitro and in vivo models of Parkinson disease

(2015) Zaijun Zhang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Interrelation of Oxidative Stress and Inflammation in Neurodegenerative Disease: Role of TNF

(2015) Roman Fischer et al.   Oxidative Medicine and Cellular Longevity

Protective effect of n-butanol extract from Alpinia oxyphylla on learning and memory impairments

(2015) Shao-huai Shi et al.   PHYSIOLOGY & BEHAVIOR

Protocatechuic acid ameliorates neurocognitive functions impairment induced by chronic intermittent hypoxia

(2015) Xue Yin et al.   Scientific Reports

The Role of Oxidative Stress in Neurodegenerative Diseases

(2015) Geon Ha Kim et al.   Experimental Neurobiology

The pharmacokinetics of anthocyanins and their metabolites in humans

(2014) R M de Ferrars et al.   BRITISH JOURNAL OF PHARMACOLOGY

Bioavailability of anthocyanins

(2014) Jim Fang   DRUG METABOLISM REVIEWS

Hibiscus sabdariffa L. – A phytochemical and pharmacological review

(2014) Inês Da-Costa-Rocha et al.   FOOD CHEMISTRY

Protocatechuic acid improves cognitive deficits and attenuates amyloid deposits, inflammatory response in aged AβPP/PS1 double transgenic mice

(2014) Yu Song et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Protocatechuic acid exerts a cardioprotective effect in type 1 diabetic rats

(2014) Yoswaris Semaming et al.   JOURNAL OF ENDOCRINOLOGY

Isoprostanes and Neuroprostanes as Biomarkers of Oxidative Stress in Neurodegenerative Diseases

(2014) Elżbieta Miller et al.   Oxidative Medicine and Cellular Longevity

Oxidative Stress and Neurodegenerative Disorders

(2013) Jie Li et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Oil palm phenolics confer neuroprotective effects involving cognitive and motor functions in mice

(2013) Soon-Sen Leow et al.   NUTRITIONAL NEUROSCIENCE

Neuroprotective Effects of Protocatechuic Aldehyde against Neurotoxin-Induced Cellular and Animal Models of Parkinson’s Disease

(2013) Xin Zhao et al.   PLoS One

Monoamine Oxidase and Dopamine β-Hydroxylase Inhibitors from the Fruits of Gardenia jasminoides

(2012) Ji-Ho Kim et al.   Biomolecules & Therapeutics

Contribution of gut bacteria to the metabolism of cyanidin 3-glucoside in human microbiota-associated rats

(2012) Laura Hanske et al.   BRITISH JOURNAL OF NUTRITION

A Brief Overview of Tyrosine Hydroxylase and α-Synuclein in the Parkinsonian Brain

(2012) Wajihullah Khan et al.   CNS & Neurological Disorders-Drug Targets

Protocatechuic Acid and Human Disease Prevention: Biological Activities and Molecular Mechanisms

(2012) R. Masella et al.   CURRENT MEDICINAL CHEMISTRY

Dietary Polyphenols as Modulators of Brain Functions: Biological Actions and Molecular Mechanisms Underpinning Their Beneficial Effects

(2012) David Vauzour   Oxidative Medicine and Cellular Longevity

On the free radical scavenging mechanism of protocatechuic acid, regeneration of the catechol group in aqueous solution

(2012) Annia Galano et al.   THEORETICAL CHEMISTRY ACCOUNTS

Antiglycative Effects of Protocatechuic Acid in the Kidneys of Diabetic Mice

(2011) Chia-Yu Lin et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

MAO-inhibitors in Parkinson's Disease

(2011) Peter Riederer et al.   Experimental Neurobiology

Berry flavonoids and phenolics: bioavailability and evidence of protective effects

(2010) Daniele Del Rio et al.   BRITISH JOURNAL OF NUTRITION

Alzheimer Disease

(2010) Rudy J. Castellani et al.   DM DISEASE-A-MONTH

Anti-inflammatory effects of black rice, cyanidin-3-O-β-d-glycoside, and its metabolites, cyanidin and protocatechuic acid

(2010) Sung-Won Min et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Cell-to-cell transmission of non-prion protein aggregates

(2010) Seung-Jae Lee et al.   Nature Reviews Neurology

EGCG remodels mature α-synuclein and amyloid-β fibrils and reduces cellular toxicity

(2010) Jan Bieschke et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glutamate and Neurotrophic Factors in Neuronal Plasticity and Disease

(2009) Mark P. Mattson   Annals of the New York Academy of Sciences

Protocatechuic Acid Inhibits Rat Pheochromocytoma Cell Damage Induced by a Dopaminergic Neurotoxin

(2009) Hong-Ning Zhang et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Bioconversion of anthocyanin glycosides by Bifidobacteria and Lactobacillus

(2009) Marta Ávila et al.   FOOD RESEARCH INTERNATIONAL

Anticoagulatory, Antiinflammatory, and Antioxidative Effects of Protocatechuic Acid in Diabetic Mice

(2009) Chia-Yu Lin et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

The bioactivity of dietary anthocyanins is likely to be mediated by their degradation products

(2009) Colin D. Kay et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Brain-derived neurotrophic factor in neurodegenerative diseases

(2009) Chiara Zuccato et al.   Nature Reviews Neurology

Anthocyanins: Are They Beneficial in Treating Ethanol Neurotoxicity?

(2009) Gang Chen et al.   NEUROTOXICITY RESEARCH