Equol Enhances Apoptosis-inducing Activity of Genistein by Increasing Bax/Bcl-xL Expression Ratio in MCF-7 Human Breast Cancer Cells

S-equol, a Secondary Metabolite of Natural Anticancer Isoflavone Daidzein, Inhibits Prostate Cancer Growth In Vitro and In Vivo, Though Activating the Akt/FOXO3a Pathway

(2016) Zongliang Lu et al.   CURRENT CANCER DRUG TARGETS

Abstract 909: Mechanistic study of synergistic interaction between genistein and equol in MCF-7 human breast cancer cells in vitro

(2015) MISAKI ONO et al.   CANCER RESEARCH

Soy Isoflavones and Breast Cancer Cell Lines: Molecular Mechanisms and Future Perspectives

(2015) Alina Uifălean et al.   MOLECULES

Equol inhibits proliferation of human gastric carcinoma cellsviamodulating Akt pathway

(2015) Zhi-Ping Yang   WORLD JOURNAL OF GASTROENTEROLOGY

Genistein induces apoptosis by the inactivation of the IGF-1R/p-Akt signaling pathway in MCF-7 human breast cancer cells

(2015) Jun Chen et al.   Food & Function

Equol induces apoptosis in human hepatocellular carcinoma SMMC-7721 cells through the intrinsic pathway and the endoplasmic reticulum stress pathway

(2014) Xiao-Lin Liang et al.   ANTI-CANCER DRUGS

Targeting the PI3K/AKT/mTOR pathway in estrogen receptor-positive breast cancer

(2014) Eva Maria Ciruelos Gil   CANCER TREATMENT REVIEWS

Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012

(2014) Jacques Ferlay et al.   INTERNATIONAL JOURNAL OF CANCER

Genistein induces apoptosis and autophagy in human breast MCF-7 cells by modulating the expression of proapoptotic factors and oxidative stress enzymes

(2014) R. F. Prietsch et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Association between Soy Isoflavone Intake and Breast Cancer Risk for Pre- and Post-Menopausal Women: A Meta-Analysis of Epidemiological Studies

(2014) Meinan Chen et al.   PLoS One

Differential anti-tumor activities of curcumin against Ras- and Src-activated human adenocarcinoma cells

(2013) Misaki Ono et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Equol enhances tamoxifen’s anti-tumor activity by induction of caspase-mediated apoptosis in MCF-7 breast cancer cells

(2013) Christiana Charalambous et al.   BMC CANCER

Genistein-induced G2/M cell cycle arrest of human intestinal colon cancer Caco-2 cells is associated with Cyclin B1 and Chk2 down-regulation

(2013) Junkyu Han et al.   CYTOTECHNOLOGY

Mechanisms enforcing the estrogen receptor β selectivity of botanical estrogens

(2013) Yan Jiang et al.   FASEB JOURNAL

Genistein Induces G2/M Arrest in Gastric Cancer Cells by Increasing the Tumor Suppressor PTEN Expression

(2013) Yan-Long Liu et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Effects of Dietary Genistein on Hormone-Dependent Rat Mammary Carcinogenesis Induced by Ethyl Methanesulphonate

(2012) Misaki Ono et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Soy isoflavone phase II metabolism differs between rodents and humans: implications for the effect on breast cancer risk

(2011) Kenneth DR Setchell et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Risks and benefits of dietary isoflavones for cancer

(2011) Susanne Andres et al.   CRITICAL REVIEWS IN TOXICOLOGY

Effects of S-equol and natural S-equol supplement (SE5-OH) on the growth of MCF-7 in vitro and as tumors implanted into ovariectomized athymic mice

(2011) Atsuko Onoda et al.   FOOD AND CHEMICAL TOXICOLOGY

Anticancer mechanism of equol in 7,12-dimethylbenz(a)anthracene-treated animals

(2011) Eun Choi   INTERNATIONAL JOURNAL OF ONCOLOGY

Disposition of soy isoflavones in normal human breast tissue

(2010) Selin Bolca et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Soy isoflavones consumption and risk of breast cancer incidence or recurrence: a meta-analysis of prospective studies

(2010) Jia-Yi Dong et al.   BREAST CANCER RESEARCH AND TREATMENT

Estrogen receptor β causes a G2 cell cycle arrest by inhibiting CDK1 activity through the regulation of cyclin B1, GADD45A, and BTG2

(2010) Sreenivasan Paruthiyil et al.   BREAST CANCER RESEARCH AND TREATMENT

Equol: Pharmacokinetics and Biological Actions

(2010) Kenneth D. R. Setchell et al.   JOURNAL OF NUTRITION

Daidzein induces MCF-7 breast cancer cell apoptosis via the mitochondrial pathway

(2009) S. Jin et al.   ANNALS OF ONCOLOGY

Effects of diverse dietary phytoestrogens on cell growth, cell cycle and apoptosis in estrogen-receptor-positive breast cancer cells

(2009) Takako Sakamoto et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Plasma Isoflavone Level and Subsequent Risk of Breast Cancer Among Japanese Women: A Nested Case-Control Study From the Japan Public Health Center-Based Prospective Study Group

(2008) Motoki Iwasaki et al.   JOURNAL OF CLINICAL ONCOLOGY