ECOdrug: a database connecting drugs and conservation of their targets across species

In Vitro Developmental Toxicology Screens: A Report on the Progress of the Methodology and Future Applications

(2016) Cindy Zhang et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Use of acute and chronic ecotoxicity data in environmental risk assessment of pharmaceuticals

(2016) Jessica Vestel et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Pharmaceuticals in the environment-Global occurrences and perspectives

(2016) Tim aus der Beek et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Standardized benchmarking in the quest for orthologs

(2016) Adrian M Altenhoff et al.   NATURE METHODS

UniProt: the universal protein knowledgebase

(2016)   NUCLEIC ACIDS RESEARCH

Editor’s Highlight: Sequence Alignment to Predict Across Species Susceptibility (SeqAPASS): A Web-Based Tool for Addressing the Challenges of Cross-Species Extrapolation of Chemical Toxicity

(2016) Carlie A. LaLone et al.   TOXICOLOGICAL SCIENCES

Ensembl comparative genomics resources

(2016) Javier Herrero et al.   Database-The Journal of Biological Databases and Curation

Rock, Paper, Scissors: Harnessing Complementarity in Ortholog Detection Methods Improves Comparative Genomic Inference

(2015) M. Cyrus Maher et al.   G3-Genes Genomes Genetics

OrthoDB v8: update of the hierarchical catalog of orthologs and the underlying free software

(2014) Evgenia V. Kriventseva et al.   NUCLEIC ACIDS RESEARCH

InParanoid 8: orthology analysis between 273 proteomes, mostly eukaryotic

(2014) Erik L.L. Sonnhammer et al.   NUCLEIC ACIDS RESEARCH

Species-Specific Expansion and Molecular Evolution of the 3-hydroxy-3-methylglutaryl Coenzyme A Reductase (HMGR) Gene Family in Plants

(2014) Wei Li et al.   PLoS One

Functional and evolutionary implications of gene orthology

(2013) Toni Gabaldón et al.   NATURE REVIEWS GENETICS

DrugBank 4.0: shedding new light on drug metabolism

(2013) Vivian Law et al.   NUCLEIC ACIDS RESEARCH

Analysis Tool Web Services from the EMBL-EBI

(2013) Hamish McWilliam et al.   NUCLEIC ACIDS RESEARCH

The ChEMBL bioactivity database: an update

(2013) A. Patrícia Bento et al.   NUCLEIC ACIDS RESEARCH

A multi-endpoint in vivo larval zebrafish (Danio rerio) model for the assessment of integrated cardiovascular function

(2013) Thomas Parker et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS

Pharmaceuticals and Personal Care Products in the Environment: What Are the Big Questions?

(2012) Alistair B.A. Boxall et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Computational methods for Gene Orthology inference

(2011) D. M. Kristensen et al.   BRIEFINGS IN BIOINFORMATICS

Mapping identifiers for the integration of genomic datasets with the R/Bioconductor package biomaRt

(2009) Steffen Durinck et al.   Nature Protocols

Ensembl Genomes: Extending Ensembl across the taxonomic space

(2009) P. J. Kersey et al.   NUCLEIC ACIDS RESEARCH

Evolutionary Conservation of Human Drug Targets in Organisms used for Environmental Risk Assessments

(2008) Lina Gunnarsson et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Validation of a larval zebrafish locomotor assay for assessing the seizure liability of early-stage development drugs

(2008) Matthew J. Winter et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS