2′-Fluoroarabinonucleic acid modification traps G-quadruplex and i-motif structures in human telomeric DNA

4n–1 Is a “Sweet Spot” in DNA i-Motif Folding of 2′-Deoxycytidine Homopolymers

(2017) Aaron M. Fleming et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Consequences of Overlapping G-Quadruplexes and i-Motifs in the Platelet-Derived Growth Factor Receptor β Core Promoter Nuclease Hypersensitive Element Can Explain the Unexpected Effects of Mutations and Provide Opportunities for Selective Targeting of Both Structures by Small Molecules To Downregulate Gene Expression

(2017) Robert V. Brown et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Insight into the Complexity of the i-Motif and G-Quadruplex DNA Structures Formed in the KRAS Promoter and Subsequent Drug-Induced Gene Repression

(2017) Christine E. Kaiser et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

DNA G-quadruplexes in the human genome: detection, functions and therapeutic potential

(2017) Robert Hänsel-Hertsch et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Identification of multiple genomic DNA sequences which form i-motif structures at neutral pH

(2017) Elisé P. Wright et al.   NUCLEIC ACIDS RESEARCH

Topological impact of noncanonical DNA structures on Klenow fragment of DNA polymerase

(2017) Shuntaro Takahashi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mutually Exclusive Formation of G-Quadruplex and i-Motif Is a General Phenomenon Governed by Steric Hindrance in Duplex DNA

(2016) Yunxi Cui et al.   BIOCHEMISTRY

Structural Insights into the Quadruplex–Duplex 3′ Interface Formed from a Telomeric Repeat: A Potential Molecular Target

(2016) Irene Russo Krauss et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Mechanosensor Mechanism Controls the G-Quadruplex/i-Motif Molecular Switch in the MYC Promoter NHE III1

(2016) Caleb Sutherland et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Assembly of supramolecular DNA complexes containing both G-quadruplexes and i-motifs by enhancing the G-repeat-bearing capacity of i-motifs

(2016) Yanwei Cao et al.   NUCLEIC ACIDS RESEARCH

Stabilization of i-motif structures by 2′-β-fluorination of DNA

(2016) Hala Abou Assi et al.   NUCLEIC ACIDS RESEARCH

Zika Virus Genomic RNA Possesses Conserved G-Quadruplexes Characteristic of the Flaviviridae Family

(2016) Aaron M. Fleming et al.   ACS Infectious Diseases

Direct visualization of both DNA and RNA quadruplexes in human cells via an uncommon spectroscopic method

(2016) Aurélien Laguerre et al.   Scientific Reports

Centromeric Alpha-Satellite DNA Adopts Dimeric i-Motif Structures Capped by AT Hoogsteen Base Pairs

(2015) Miguel Garavís et al.   CHEMISTRY-A EUROPEAN JOURNAL

Fluorescent Probe for Proton-Coupled DNA Folding Revealing Slow Exchange of i-Motif and Duplex Structures

(2015) Guillaume Mata et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Human telomere biology: A contributory and interactive factor in aging, disease risks, and protection

(2015) E. H. Blackburn et al.   SCIENCE

The structure of an endogenous Drosophila centromere reveals the prevalence of tandemly repeated sequences able to form i-motifs

(2015) Miguel Garavís et al.   Scientific Reports

DNA Nanotechnology Based on i-Motif Structures

(2014) Yuanchen Dong et al.   ACCOUNTS OF CHEMICAL RESEARCH

The Transcriptional Complex Between the BCL2 i-Motif and hnRNP LL Is a Molecular Switch for Control of Gene Expression That Can Be Modulated by Small Molecules

(2014) Hyun-Jin Kang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Silver cations fold i-motif at neutral pH

(2013) Henry A. Day et al.   CHEMICAL COMMUNICATIONS

Quantitative visualization of DNA G-quadruplex structures in human cells

(2013) Giulia Biffi et al.   Nature Chemistry

Distance-dependent duplex DNA destabilization proximal to G-quadruplex/ i -motif sequences

(2013) Sebastian L. B. König et al.   NUCLEIC ACIDS RESEARCH

G-Quadruplex and i-Motif Are Mutually Exclusive in ILPR Double-Stranded DNA

(2012) Soma Dhakal et al.   BIOPHYSICAL JOURNAL

2′-F-ANA-guanosine and 2′-F-guanosine as powerful tools for structural manipulation of G-quadruplexes

(2012) Christopher Jacques Lech et al.   CHEMICAL COMMUNICATIONS

I-Motif formation in gene promoters: unusually stable formation in sequences complementary to known G-quadruplexes

(2012) John A. Brazier et al.   CHEMICAL COMMUNICATIONS

The solution structure of double helical arabino nucleic acids (ANA and 2′F-ANA): effect of arabinoses in duplex-hairpin interconversion

(2012) Nerea Martín-Pintado et al.   NUCLEIC ACIDS RESEARCH

Topological Characterization of Nucleic Acid G-Quadruplexes by UV Absorption and Circular Dichroism

(2011) Andreas Ioannis Karsisiotis et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Targeting G-quadruplexes in gene promoters: a novel anticancer strategy?

(2011) Shankar Balasubramanian et al.   NATURE REVIEWS DRUG DISCOVERY

Telomere Extension Occurs at Most Chromosome Ends and Is Uncoupled from Fill-In in Human Cancer Cells

(2009) Yong Zhao et al.   CELL

pH-Modulated Watson–Crick Duplex–Quadruplex Equilibria of Guanine-Rich and Cytosine-Rich DNA Sequences 140 Base Pairs Upstream of thec-kitTranscription Initiation Site

(2009) Pavel Bucek et al.   CHEMISTRY-A EUROPEAN JOURNAL

The Importance of Negative Superhelicity in Inducing the Formation of G-Quadruplex and i-Motif Structures in the c-Myc Promoter: Implications for Drug Targeting and Control of Gene Expression

(2009) Daekyu Sun et al.   JOURNAL OF MEDICINAL CHEMISTRY

The i-Motif in thebcl-2P1 Promoter Forms an Unexpectedly Stable Structure with a Unique 8:5:7 Loop Folding Pattern

(2009) Samantha Kendrick et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Circular dichroism and conformational polymorphism of DNA

(2009) J. Kypr et al.   NUCLEIC ACIDS RESEARCH

G-quadruplex structures: in vivo evidence and function

(2009) Hans J. Lipps et al.   TRENDS IN CELL BIOLOGY

Intramolecularly folded G-quadruplex and i-motif structures in the proximal promoter of the vascular endothelial growth factor gene

(2008) K. Guo et al.   NUCLEIC ACIDS RESEARCH

Effect of loop length variation on quadruplex-Watson Crick duplex competition

(2008) Niti Kumar et al.   NUCLEIC ACIDS RESEARCH

Targeting telomeres and telomerase

(2007) Anne De Cian et al.   BIOCHIMIE