SDM--a server for predicting effects of mutations on protein stability and malfunction

Novel TSHR mutations in consanguineous families with congenital nongoitrous hypothyroidism

(2010) Hakan Cangul et al.   CLINICAL ENDOCRINOLOGY

Performance of protein stability predictors

(2010) Sofia Khan et al.   HUMAN MUTATION

Toward Classification of BRCA1 Missense Variants Using a Biophysical Approach

(2010) Pamela J. E. Rowling et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ongoing and future developments at the Universal Protein Resource

(2010)   NUCLEIC ACIDS RESEARCH

Missense mutations in dystrophin that trigger muscular dystrophy decrease protein stability and lead to cross-  aggregates

(2010) S. M. Singh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Environment-specific amino acid substitution tables: Tertiary templates and prediction of protein folds

(2010) John Overington et al.   PROTEIN SCIENCE

Fast and accurate predictions of protein stability changes upon mutations using statistical potentials and neural networks: PoPMuSiC-2.0

(2009) Yves Dehouck et al.   BIOINFORMATICS

Stability effects of mutations and protein evolvability

(2009) Nobuhiko Tokuriki et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Mixed lineage kinase 3 gene mutations in mismatch repair deficient gastrointestinal tumours

(2009) Sérgia Velho et al.   HUMAN MOLECULAR GENETICS

Tumor risks and genotype–phenotype–proteotype analysis in 358 patients with germline mutations inSDHBandSDHD

(2009) Christopher J. Ricketts et al.   HUMAN MUTATION

A TIR Domain Variant of MyD88 Adapter-like (Mal)/TIRAP Results in Loss of MyD88 Binding and Reduced TLR2/TLR4 Signaling

(2009) Kamalpreet Nagpal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Parkinson disease-associated A30P mutation stabilizes α-synuclein against proteasomal degradation triggered by heme oxygenase-1 over-expression in human neuroblastoma cells

(2009) Wei Song et al.   JOURNAL OF NEUROCHEMISTRY

Sequencing technologies — the next generation

(2009) Michael L. Metzker   NATURE REVIEWS GENETICS

Assessing computational methods for predicting protein stability upon mutation: good on average but not in the details

(2009) V. Potapov et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Structural bioinformatics mutation analysis reveals genotype-phenotype correlations in von Hippel-Lindau disease and suggests molecular mechanisms of tumorigenesis

(2009) Julia R. Forman et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Accurate prediction of stability changes in protein mutants by combining machine learning with structure based computational mutagenesis

(2008) M. Masso et al.   BIOINFORMATICS

Stabilizing mutation of CTNNB1/beta-catenin and protein accumulation analyzed in a large series of parathyroid tumors of Swedish patients

(2008) Peyman Björklund et al.   Molecular Cancer

The complete genome of an individual by massively parallel DNA sequencing

(2008) David A. Wheeler et al.   NATURE

Robust prediction of mutation-induced protein stability change by property encoding of amino acids

(2008) S. Kang et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Satisfaction of hydrogen-bonding potential influences the conservation of polar sidechains

(2008) Catherine L. Worth et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS