In mammalian foetal testes, SOX9 regulates expression of its target genes by binding to genomic regions with conserved signatures

Efficient Intracellular Delivery of Native Proteins

(2015) Diego S. D’Astolfo et al.   CELL

Direct Lineage Reprogramming: Strategies, Mechanisms, and Applications

(2015) Jun Xu et al.   Cell Stem Cell

Sox9 Controls Self-Renewal of Oncogene Targeted Cells and Links Tumor Initiation and Invasion

(2015) Jean-Christophe Larsimont et al.   Cell Stem Cell

Sexual Cell-Fate Reprogramming in the Ovary by DMRT1

(2015) Robin E. Lindeman et al.   CURRENT BIOLOGY

SOX9 modulates the expression of key transcription factors required for heart valve development

(2015) V. C. Garside et al.   DEVELOPMENT

Female-to-male sex reversal in mice caused by transgenic overexpression of Dmrt1

(2015) L. Zhao et al.   DEVELOPMENT

Combined Loss of the GATA4 and GATA6 Transcription Factors in Male Mice Disrupts Testicular Development and Confers Adrenal-Like Function in the Testes

(2015) Maria B. Padua et al.   ENDOCRINOLOGY

FGFR2mutation in 46,XY sex reversal with craniosynostosis

(2015) Stefan Bagheri-Fam et al.   HUMAN MOLECULAR GENETICS

An ancient protein-DNA interaction underlying metazoan sex determination

(2015) Mark W Murphy et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Context-specific role of SOX9 in NF-Y mediated gene regulation in colorectal cancer cells

(2015) Zhongcheng Shi et al.   NUCLEIC ACIDS RESEARCH

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

Why weight? Modelling sample and observational level variability improves power in RNA-seq analyses

(2015) Ruijie Liu et al.   NUCLEIC ACIDS RESEARCH

An ancient protein-DNA interaction underlying metazoan sex determination

(2015) Mark W Murphy et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Distinct Transcriptional Programs Underlie Sox9 Regulation of the Mammalian Chondrocyte

(2015) Shinsuke Ohba et al.   Cell Reports

HTSeq--a Python framework to work with high-throughput sequencing data

(2014) S. Anders et al.   BIOINFORMATICS

Trimmomatic: a flexible trimmer for Illumina sequence data

(2014) Anthony M. Bolger et al.   BIOINFORMATICS

FOXL2 Is a Female Sex-Determining Gene in the Goat

(2014) Laurent Boulanger et al.   CURRENT BIOLOGY

SOX9: a stem cell transcriptional regulator of secreted niche signaling factors

(2014) M. Kadaja et al.   GENES & DEVELOPMENT

Loss of Function Mutation in the Palmitoyl-Transferase HHAT Leads to Syndromic 46,XY Disorder of Sex Development by Impeding Hedgehog Protein Palmitoylation and Signaling

(2014) Patrick Callier et al.   PLoS Genetics

voom: precision weights unlock linear model analysis tools for RNA-seq read counts

(2014) Charity W Law et al.   GENOME BIOLOGY

Interaction between DMRT1 function and genetic background modulates signaling and pluripotency to control tumor susceptibility in the fetal germ line

(2013) Anthony D. Krentz et al.   DEVELOPMENTAL BIOLOGY

Building the mammalian testis: origins, differentiation, and assembly of the component cell populations

(2013) T. Svingen et al.   GENES & DEVELOPMENT

Epigenetic Regulation of Mouse Sex Determination by the Histone Demethylase Jmjd1a

(2013) S. Kuroki et al.   SCIENCE

Novel PCR Assay for Determining the Genetic Sex of Mice

(2013) L. McFarlane et al.   Sexual Development

Fine Time Course Expression Analysis Identifies Cascades of Activation and Repression and Maps a Putative Regulator of Mammalian Sex Determination

(2013) Steven C. Munger et al.   PLoS Genetics

TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions

(2013) Daehwan Kim et al.   GENOME BIOLOGY

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Oncogenicity of the Developmental Transcription Factor Sox9

(2012) A. Matheu et al.   CANCER RESEARCH

Direct Reprogramming of Fibroblasts into Embryonic Sertoli-like Cells by Defined Factors

(2012) Yosef Buganim et al.   Cell Stem Cell

A Sox9/Fgf feed-forward loop maintains pancreatic organ identity

(2012) P. A. Seymour et al.   DEVELOPMENT

GADD45G Functions in Male Sex Determination by Promoting p38 Signaling and Sry Expression

(2012) Mathias S. Gierl et al.   DEVELOPMENTAL CELL

Gadd45γ and Map3k4 Interactions Regulate Mouse Testis Determination via p38 MAPK-Mediated Control of Sry Expression

(2012) Nick Warr et al.   DEVELOPMENTAL CELL

Sex and the circuitry: progress toward a systems-level understanding of vertebrate sex determination

(2012) Steven C. Munger et al.   Wiley Interdisciplinary Reviews-Systems Biology and Medicine

Temporal Transcriptional Profiling of Somatic and Germ Cells Reveals Biased Lineage Priming of Sexual Fate in the Fetal Mouse Gonad

(2012) Samantha A. Jameson et al.   PLoS Genetics

Testicular Differentiation Occurs in Absence of R-spondin1 and Sox9 in Mouse Sex Reversals

(2012) Rowena Lavery et al.   PLoS Genetics

Epigenetics in Alternative Pre-mRNA Splicing

(2011) Reini F. Luco et al.   CELL

Sex determination in insects: a binary decision based on alternative splicing

(2011) Helen K Salz   CURRENT OPINION IN GENETICS & DEVELOPMENT

Defective survival of proliferating Sertoli cells and androgen receptor function in a mouse model of the ATR-X syndrome

(2011) Stefan Bagheri-Fam et al.   HUMAN MOLECULAR GENETICS

Genomic characterization of Wilms' tumor suppressor 1 targets in nephron progenitor cells during kidney development

(2010) S. Hartwig et al.   DEVELOPMENT

ChIP-on-chip analysis reveals angiopoietin 2 (Ang2, ANGPT2) as a novel target of steroidogenic factor-1 (SF-1, NR5A1) in the human adrenal gland

(2010) Bruno Ferraz-de-Souza et al.   FASEB JOURNAL

Analysis and design of RNA sequencing experiments for identifying isoform regulation

(2010) Yarden Katz et al.   NATURE METHODS

Regulation of Alternative Splicing by Histone Modifications

(2010) R. F. Luco et al.   SCIENCE

A scaling normalization method for differential expression analysis of RNA-seq data

(2010) Mark D Robinson et al.   GENOME BIOLOGY

An endoderm-specific transcriptional enhancer from the mouseGata4gene requires GATA and homeodomain protein-binding sites for function in vivo

(2009) Anabel Rojas et al.   DEVELOPMENTAL DYNAMICS

DAX-1 and SOX6 molecular interplay results in an antagonistic effect in pre-mRNA splicing

(2009) Kenji Ohe et al.   DEVELOPMENTAL DYNAMICS

A genome-wide RNAi screen identifies a new transcriptional module required for self-renewal

(2009) G. Hu et al.   GENES & DEVELOPMENT

Sox10 gain-of-function causes XX sex reversal in mice: implications for human 22q-linked disorders of sex development

(2009) Juan Carlos Polanco et al.   HUMAN MOLECULAR GENETICS

The avian Z-linked gene DMRT1 is required for male sex determination in the chicken

(2009) Craig A. Smith et al.   NATURE

Three-Dimensional Resolution Doubling in Wide-Field Fluorescence Microscopy by Structured Illumination

(2008) Mats G.L. Gustafsson et al.   BIOPHYSICAL JOURNAL

Testis cord differentiation after the sex determination stage is independent of Sox9 but fails in the combined absence of Sox9 and Sox8

(2008) Francisco Barrionuevo et al.   DEVELOPMENTAL BIOLOGY

Paraspeckle protein p54nrb links Sox9-mediated transcription with RNA processing during chondrogenesis in mice

(2008) Kenji Hata et al.   JOURNAL OF CLINICAL INVESTIGATION

Sex determination involves synergistic action of SRY and SF1 on a specific Sox9 enhancer

(2008) Ryohei Sekido et al.   NATURE

Model-based Analysis of ChIP-Seq (MACS)

(2008) Yong Zhang et al.   GENOME BIOLOGY