Strong transcription blockage mediated by R-loop formation within a G-rich homopurine–homopyrimidine sequence localized in the vicinity of the promoter

Nascent Connections: R-Loops and Chromatin Patterning

(2016) Frédéric Chédin   TRENDS IN GENETICS

The Yin and Yang of R-loop biology

(2015) Lorenzo Costantino et al.   CURRENT OPINION IN CELL BIOLOGY

R loops: new modulators of genome dynamics and function

(2015) José M. Santos-Pereira et al.   NATURE REVIEWS GENETICS

G-quadruplexes and their regulatory roles in biology

(2015) Daniela Rhodes et al.   NUCLEIC ACIDS RESEARCH

Breaking bad: R-loops and genome integrity

(2015) Julie Sollier et al.   TRENDS IN CELL BIOLOGY

Pack, unpack, bend, twist, pull, push: the physical side of gene expression

(2014) Christophe Lavelle   CURRENT OPINION IN GENETICS & DEVELOPMENT

PNA binding to the non-template DNA strand interferes with transcription, suggesting a blockage mechanism mediated by R-loop formation

(2014) Boris P. Belotserkovskii et al.   MOLECULAR CARCINOGENESIS

DNA Sequences That Interfere with Transcription: Implications for Genome Function and Stability

(2013) Boris P. Belotserkovskii et al.   CHEMICAL REVIEWS

Supercoiling in DNA and chromatin

(2013) Nick Gilbert et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Genetic Determinants and Cellular Constraints in Noisy Gene Expression

(2013) A. Sanchez et al.   SCIENCE

The G4 Genome

(2013) Nancy Maizels et al.   PLoS Genetics

R Loops: From Transcription Byproducts to Threats to Genome Stability

(2012) Andrés Aguilera et al.   MOLECULAR CELL

Transcription blockage by homopurine DNA sequences: role of sequence composition and single-strand breaks

(2012) Boris P. Belotserkovskii et al.   NUCLEIC ACIDS RESEARCH

Anchoring Nascent RNA to the DNA Template Could Interfere with Transcription

(2011) Boris P. Belotserkovskii et al.   BIOPHYSICAL JOURNAL

Transcription-induced DNA toxicity at trinucleotide repeats

(2011) Yunfu Lin et al.   CELL CYCLE

Mechanisms and implications of transcription blockage by guanine-rich DNA sequences

(2010) B. P. Belotserkovskii et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Competition between the RNA Transcript and the Nontemplate DNA Strand during R-Loop Formation In Vitro: a Nick Can Serve as a Strong R-Loop Initiation Site

(2009) D. Roy et al.   MOLECULAR AND CELLULAR BIOLOGY

G4-forming Sequences in the Non-transcribed DNA Strand Pose Blocks to T7 RNA Polymerase and Mammalian RNA Polymerase II

(2008) Silvia Tornaletti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY