Expression of short hairpin RNAs using the compact architecture of retroviral microRNA genes

RNA Interference (RNAi)-Based Therapeutics: Delivering on the Promise?

(2016) Maggie L. Bobbin et al.   Annual Review of Pharmacology and Toxicology

DUSP11 activity on triphosphorylated transcripts promotes Argonaute association with noncanonical viral microRNAs and regulates steady-state levels of cellular noncoding RNAs

(2016) James M. Burke et al.   GENES & DEVELOPMENT

Advanced Design of Dumbbell-shaped Genetic Minimal Vectors Improves Non-coding and Coding RNA Expression

(2016) Xiaoou Jiang et al.   MOLECULAR THERAPY

Bovine Leukemia Virus Small Noncoding RNAs Are Functional Elements That Regulate Replication and Contribute to Oncogenesis In Vivo

(2016) Nicolas A. Gillet et al.   PLoS Pathogens

Sequence Features of Drosha and Dicer Cleavage Sites Affect the Complexity of IsomiRs

(2015) Julia Starega-Roslan et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Identification, validation, and characterization of noncanonical miRNAs

(2015) James M. Burke et al.   METHODS

Knocking down disease: a progress report on siRNA therapeutics

(2015) Anders Wittrup et al.   NATURE REVIEWS GENETICS

Expression of CRISPR/Cas single guide RNAs using small tRNA promoters

(2015) Adam L. Mefferd et al.   RNA

A conserved RNA polymerase III promoter required for gammaherpesvirus TMER transcription and microRNA processing

(2014) Kevin W. Diebel et al.   GENE

Identification of tri-phosphatase activity in the biogenesis of retroviral microRNAs and RNAP III-generated shRNAs

(2014) James M. Burke et al.   NUCLEIC ACIDS RESEARCH

Small-interfering RNAs (siRNAs) as a promising tool for ocular therapy

(2013) A Guzman-Aranguez et al.   BRITISH JOURNAL OF PHARMACOLOGY

Short Hairpin RNA Gene Silencing of Prolyl Hydroxylase-2 with a Minicircle Vector Improves Neovascularization of Hindlimb Ischemia

(2013) Maarten A. Lijkwan et al.   HUMAN GENE THERAPY

Recombinant AAV as a Platform for Translating the Therapeutic Potential of RNA Interference

(2013) Florie Borel et al.   MOLECULAR THERAPY

Adeno-associated virus-delivered polycistronic microRNA-clusters for knockdown of vascular endothelial growth factor in vivo

(2012) Maria Pihlmann et al.   JOURNAL OF GENE MEDICINE

Safe, Long-term Hepatic Expression of Anti-HCV shRNA in a Nonhuman Primate Model

(2012) David A Suhy et al.   MOLECULAR THERAPY

RNA virus microRNA that mimics a B-cell oncomiR

(2012) R. P. Kincaid et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Double Knockdown of Prolyl Hydroxylase and Factor-Inhibiting Hypoxia-Inducible Factor With Nonviral Minicircle Gene Therapy Enhances Stem Cell Mobilization and Angiogenesis After Myocardial Infarction

(2011) M. Huang et al.   CIRCULATION

RNA polymerase III transcription control elements: Themes and variations

(2011) Andrea Orioli et al.   GENE

Combination therapy utilizing shRNA knockdown and an optimized resistant transgene for rescue of diseases caused by misfolded proteins

(2011) C. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nonintegrating Knockdown and Customized Scaffold Design Enhances Human Adipose-Derived Stem Cells in Skeletal Repair

(2011) Benjamin Levi et al.   STEM CELLS

Engineering RNA for Targeted siRNA Delivery and Medical Application

(2010) Peixuan Guo et al.   ADVANCED DRUG DELIVERY REVIEWS

Transfection of shRNA-encoding Minivector DNA of a few hundred base pairs to regulate gene expression in lymphoma cells

(2010) N Zhao et al.   GENE THERAPY

A Mammalian Herpesvirus Uses Noncanonical Expression and Processing Mechanisms to Generate Viral MicroRNAs

(2010) Hal P. Bogerd et al.   MOLECULAR CELL

Structural basis for 5′-nucleotide base-specific recognition of guide RNA by human AGO2

(2010) Filipp Frank et al.   NATURE

Origins and Mechanisms of miRNAs and siRNAs

(2009) Richard W. Carthew et al.   CELL

The promises and pitfalls of RNA-interference-based therapeutics

(2009) Daniela Castanotto et al.   NATURE

Mature and functional viral miRNAs transcribed from novel RNA polymerase III promoters

(2009) K. W. Diebel et al.   RNA

SHRiMP: Accurate Mapping of Short Color-space Reads

(2009) Stephen M. Rumble et al.   PLoS Computational Biology

Evolutionarily Conserved Function of a Viral MicroRNA

(2008) G. J. Seo et al.   JOURNAL OF VIROLOGY

Artificial MicroRNAs as siRNA Shuttles: Improved Safety as Compared to shRNAs In vitro and In vivo

(2008) Ryan L Boudreau et al.   MOLECULAR THERAPY

Comparative Study of Anti-hepatitis B Virus RNA Interference by Double-stranded Adeno-associated Virus Serotypes 7, 8, and 9

(2008) Chun-Chi Chen et al.   MOLECULAR THERAPY

Artificial miRNAs mitigate shRNA-mediated toxicity in the brain: Implications for the therapeutic development of RNAi

(2008) J. L. McBride et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phosphorylation of Retinoblastoma Protein by Viral Protein with Cyclin-Dependent Kinase Function

(2008) A. J. Hume et al.   SCIENCE