Structural and functional analysis of an OB-fold in human Ctc1 implicated in telomere maintenance and bone marrow syndromes

CTC1-mediated C-strand fill-in is an essential step in telomere length maintenance

(2017) Xuyang Feng et al.   NUCLEIC ACIDS RESEARCH

STN1 OB Fold Mutation Alters DNA Binding and Affects Selective Aspects of CST Function

(2016) Anukana Bhattacharjee et al.   PLoS Genetics

Structure and function of the telomeric CST complex

(2016) Cory Rice et al.   Computational and Structural Biotechnology Journal

Insights into Cdc13 dependent telomere length regulation

(2016) Mark Mason et al.   Aging-US

Oligomeric Properties of Survival Motor Neuron·Gemin2 Complexes

(2015) Kushol Gupta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The CDC13-STN1-TEN1 complex stimulates Pol α activity by promoting RNA priming and primase-to-polymerase switch

(2014) Neal F. Lue et al.   Nature Communications

Role of STN1 and DNA Polymerase α in Telomere Stability and Genome-Wide Replication in Arabidopsis

(2014) Elisa Derboven et al.   PLoS Genetics

Functional characterization of human CTC1 mutations reveals novel mechanisms responsible for the pathogenesis of the telomere disease Coats plus

(2013) Peili Gu et al.   AGING CELL

Molecular basis of telomere syndrome caused by CTC1 mutations

(2013) L.-Y. Chen et al.   GENES & DEVELOPMENT

TeloTool: a new tool for telomere length measurement from terminal restriction fragment analysis with improved probe intensity correction

(2013) Janett Göhring et al.   NUCLEIC ACIDS RESEARCH

Structure of the Human Telomeric Stn1-Ten1 Capping Complex

(2013) Christopher Bryan et al.   PLoS One

Mutations in CTC1 , Encoding the CTS Telomere Maintenance Complex Component 1, Cause Cerebroretinal Microangiopathy with Calcifications and Cysts

(2012) Anne Polvi et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Human Stn1 protects telomere integrity by promoting efficient lagging-strand synthesis at telomeres and mediating C-strand fill-in

(2012) Chenhui Huang et al.   CELL RESEARCH

Human CST promotes telomere duplex replication and general replication restart after fork stalling

(2012) Jason A Stewart et al.   EMBO JOURNAL

CTC1 deletion results in defective telomere replication, leading to catastrophic telomere loss and stem cell exhaustion

(2012) Peili Gu et al.   EMBO JOURNAL

Structure and conformational change of a replication protein A heterotrimer bound to ssDNA

(2012) J. Fan et al.   GENES & DEVELOPMENT

Mutations in the telomere capping complex in bone marrow failure and related syndromes

(2012) A. J. Walne et al.   HAEMATOLOGICA

The human CST complex is a terminator of telomerase activity

(2012) Liuh-Yow Chen et al.   NATURE

Mutations in CTC1, encoding conserved telomere maintenance component 1, cause Coats plus

(2012) Beverley H Anderson et al.   NATURE GENETICS

CTC1 Mutations in a patient with dyskeratosis congenita

(2012) Rachel B. Keller et al.   PEDIATRIC BLOOD & CANCER

Cdc13 OB2 Dimerization Required for Productive Stn1 Binding and Efficient Telomere Maintenance

(2012) Mark Mason et al.   STRUCTURE

Xenopus laevisCtc1-Stn1-Ten1 (xCST) Protein Complex Is Involved in Priming DNA Synthesis on Single-stranded DNA Template inXenopusEgg Extract

(2011) Hidenori Nakaoka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Analyses of Candida Cdc13 Orthologues Revealed a Novel OB Fold Dimer Arrangement, Dimerization-Assisted DNA Binding, and Substantial Structural Differences between Cdc13 and RPA70

(2011) E. Y. Yu et al.   MOLECULAR AND CELLULAR BIOLOGY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Structural bases of dimerization of yeast telomere protein Cdc13 and its interaction with the catalytic subunit of DNA polymerase α

(2010) Jia Sun et al.   CELL RESEARCH

Oligonucleotide/oligosaccharide-binding fold proteins: a growing family of genome guardians

(2010) Rachel Litman Flynn et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Cdc13 N-Terminal Dimerization, DNA Binding, and Telomere Length Regulation

(2010) M. T. Mitchell et al.   MOLECULAR AND CELLULAR BIOLOGY

Telomeres: protecting chromosomes against genome instability

(2010) Roderick J. O'Sullivan et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Conservation of telomere protein complexes: shuffling through evolution

(2009) Benjamin R. Linger et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

RPA-like Mammalian Ctc1-Stn1-Ten1 Complex Binds to Single-Stranded DNA and Protects Telomeres Independently of the Pot1 Pathway

(2009) Yasuyuki Miyake et al.   MOLECULAR CELL

Conserved Telomere Maintenance Component 1 Interacts with STN1 and Maintains Chromosome Ends in Higher Eukaryotes

(2009) Yulia V. Surovtseva et al.   MOLECULAR CELL

Protein structure prediction on the Web: a case study using the Phyre server

(2009) Lawrence A Kelley et al.   Nature Protocols

How Telomeres Solve the End-Protection Problem

(2009) T. de Lange   SCIENCE

STN1 protects chromosome ends in Arabidopsis thaliana

(2008) X. Song et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA