The miR-106b-25 cluster targets Smad7, activates TGF-β signaling and induces EMT and tumor initiating cell characteristics downstream of Six1 in human breast cancer

The microRNA cluster miR-106b~25 regulates adult neural stem/progenitor cell proliferation and neuronal differentiation

(2016) Jamie O. Brett et al.   Aging-US

Smad7: not only a regulator, but also a cross-talk mediator of TGF-β signalling

(2011) Xiaohua Yan et al.   BIOCHEMICAL JOURNAL

microRNA-Associated Progression Pathways and Potential Therapeutic Targets Identified by Integrated mRNA and microRNA Expression Profiling in Breast Cancer

(2011) F. M. Buffa et al.   CANCER RESEARCH

Switching TGFβ from a tumor suppressor to a tumor promoter

(2011) Gareth J Inman   CURRENT OPINION IN GENETICS & DEVELOPMENT

Small RNA-mediated regulation of iPS cell generation

(2011) Zhonghan Li et al.   EMBO JOURNAL

The Pro-Apoptotic Protein Bim Is a MicroRNA Target in Kidney Progenitors

(2011) J. Ho et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Homeoprotein Six1 Increases TGF-  Type I Receptor and Converts TGF-  Signaling from Suppressive to Supportive for Tumor Growth

(2010) D. S. Micalizzi et al.   CANCER RESEARCH

Robust one-day in situ hybridization protocol for detection of microRNAs in paraffin samples using LNA probes

(2010) Stine Jørgensen et al.   METHODS

MicroRNA miR-93 promotes tumor growth and angiogenesis by targeting integrin-β8

(2010) L Fang et al.   ONCOGENE

Identification of the miR-106b 25 MicroRNA Cluster as a Proto-Oncogenic PTEN-Targeting Intron That Cooperates with Its Host Gene MCM7 in Transformation

(2010) L. Poliseno et al.   Science Signaling

Regulation of TGF-  signaling by Smad7

(2009) X. Yan et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Role of themiR-106b-25microRNA cluster in hepatocellular carcinoma

(2009) Yang Li et al.   CANCER SCIENCE

The TGF-β paradox in human cancer: an update

(2009) Maozhen Tian et al.   Future Oncology

The miR-106b-25 Polycistron, Activated by Genomic Amplification, Functions as an Oncogene by Suppressing p21 and Bim

(2009) Takatsugu Kan et al.   GASTROENTEROLOGY

Six1 expands the mouse mammary epithelial stem/progenitor cell pool and induces mammary tumors that undergo epithelial-mesenchymal transition

(2009) Erica L. McCoy et al.   JOURNAL OF CLINICAL INVESTIGATION

The Six1 homeoprotein induces human mammary carcinoma cells to undergo epithelial-mesenchymal transition and metastasis in mice through increasing TGF-β signaling

(2009) Douglas S. Micalizzi et al.   JOURNAL OF CLINICAL INVESTIGATION

MicroRNA expression profile of bronchioalveolar stem cells from mouse lung

(2008) Shen Qian et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

E2F1-Regulated MicroRNAs Impair TGFβ-Dependent Cell-Cycle Arrest and Apoptosis in Gastric Cancer

(2008) Fabio Petrocca et al.   CANCER CELL

Six1 Overexpression in Mammary Cells Induces Genomic Instability and Is Sufficient for Malignant Transformation

(2008) R. D. Coletta et al.   CANCER RESEARCH

Epithelial-Mesenchymal Transition in Breast Cancer Relates to the Basal-like Phenotype

(2008) D. Sarrio et al.   CANCER RESEARCH

The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells

(2008) Sendurai A. Mani et al.   CELL

TGFβ Primes Breast Tumors for Lung Metastasis Seeding through Angiopoietin-like 4

(2008) David Padua et al.   CELL

TGFβ in Cancer

(2008) Joan Massagué   CELL

Module Map of Stem Cell Genes Guides Creation of Epithelial Cancer Stem Cells

(2008) David J. Wong et al.   Cell Stem Cell

Implications of the Cancer Stem-Cell Hypothesis for Breast Cancer Prevention and Therapy

(2008) Madhuri Kakarala et al.   JOURNAL OF CLINICAL ONCOLOGY