A biphosphinic ruthenium complex with potent anti-bacterial and anti-cancer activity

Aryl-Substituted Ruthenium(II) Complexes: A Strategy for Enhanced Photocleavage and Efficient DNA Binding

(2017) Felipe Diógenes Abreu et al.   INORGANIC CHEMISTRY

Preclinical safety evaluation of IQG-607 in rats: Acute and repeated dose toxicity studies

(2017) Valnês S. Rodrigues-Junior et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Thiol-Activated HNO Release from a Ruthenium Antiangiogenesis Complex and HIF-1α Inhibition for Cancer Therapy

(2016) Eduardo Henrique Silva Sousa et al.   ACS Chemical Biology

Antimicrobial Activity of the Manganese Photoactivated Carbon Monoxide-Releasing Molecule [Mn(CO)3(tpa-κ3N)]+ Against a Pathogenic Escherichia coli that Causes Urinary Infections

(2016) Mariana Tinajero-Trejo et al.   ANTIOXIDANTS & REDOX SIGNALING

Examining the antimicrobial activity and toxicity to animal cells of different types of CO-releasing molecules

(2016) Lígia S. Nobre et al.   DALTON TRANSACTIONS

Ruthenium(ii) complexes with dppz: from molecular photoswitch to biological applications

(2016) Guanying Li et al.   DALTON TRANSACTIONS

Ruthenium(II) bipyridine complexes with pendant anthracenyl and naphthyl moieties: A strategy for a ROS generator with DNA binding selectivity

(2016) Felipe Diógenes Abreu et al.   INORGANICA CHIMICA ACTA

In vitro and in vivo antitumor activity of a novel carbonyl ruthenium compound, the ct-[RuCl(CO)(dppb)(bipy)]PF­6[dppb=1,4-bis(diphenylphosphine)butane and bipy=2,2′-bipyridine]

(2016) Andréa P. Carnizello et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

The Smart Drug Delivery System and Its Clinical Potential

(2016) Dong Liu et al.   Theranostics

Ruthenium complexes as antimicrobial agents

(2015) Fangfei Li et al.   CHEMICAL SOCIETY REVIEWS

Noble metals in medicine: Latest advances

(2015) Serenella Medici et al.   COORDINATION CHEMISTRY REVIEWS

Non-nitric oxide based metallovasodilators: synthesis, reactivity and biological studies

(2015) Denise S. Sá et al.   DALTON TRANSACTIONS

Relaxant effect of a metal-based drug in human corpora cavernosa and its mechanism of action

(2015) A S Leitão Junior et al.   INTERNATIONAL JOURNAL OF IMPOTENCE RESEARCH

CO-releasing Metal Carbonyl Compounds as Antimicrobial Agents in the Post-antibiotic Era

(2015) Lauren K. Wareham et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cis-[RuCl(BzCN)(N–N)(P–P)]PF6 complexes: Synthesis and in vitro antitumor activity

(2015) Flávia de C. Pereira et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Folic acid-tagged protein nanoemulsions loaded with CORM-2 enhance the survival of mice bearing subcutaneous A20 lymphoma tumors

(2015) Ana Loureiro et al.   Nanomedicine-Nanotechnology Biology and Medicine

Iron Metallodrugs: Stability, Redox Activity and Toxicity against Artemia salina

(2015) Hector Aguilar Vitorino et al.   PLoS One

Design Strategies To Improve the Sensitivity of Photoactive Metal Carbonyl Complexes (photoCORMs) to Visible Light and Their Potential as CO-Donors to Biological Targets

(2014) Indranil Chakraborty et al.   ACCOUNTS OF CHEMICAL RESEARCH

Spontaneous CO Release from RuII(CO)2-Protein Complexes in Aqueous Solution, Cells, and Mice

(2014) Miguel Chaves-Ferreira et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Carbon monoxide – physiology, detection and controlled release

(2014) Stefan H. Heinemann et al.   CHEMICAL COMMUNICATIONS

Metallodrugs in Medicinal Inorganic Chemistry

(2014) Katja Dralle Mjos et al.   CHEMICAL REVIEWS

Tumor Homing Peptides as Molecular Probes for Cancer Therapeutics, Diagnostics and Theranostics

(2014) A. Gautam et al.   CURRENT MEDICINAL CHEMISTRY

Antiproliferative effects of carbon monoxide on pancreatic cancer

(2014) Libor Vítek et al.   DIGESTIVE AND LIVER DISEASE

[Fe(CN)5(isoniazid)]3−: An iron isoniazid complex with redox behavior implicated in tuberculosis therapy

(2014) Eduardo Henrique Silva Sousa et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Novel Mononuclear Ruthenium(II) Compounds in Cancer Therapy

(2013) Shyam Sunder Anchuri et al.   Asian Pacific Journal of Cancer Prevention

Exploration of the medical periodic table: towards new targets

(2013) Nicolas P. E. Barry et al.   CHEMICAL COMMUNICATIONS

Rapid CO release from a Mn(i) carbonyl complex derived from azopyridine upon exposure to visible light and its phototoxicity toward malignant cells

(2013) Samantha J. Carrington et al.   CHEMICAL COMMUNICATIONS

New ruthenium(II)/phosphines/diimines complexes: Promising antitumor (human breast cancer) and Mycobacterium tuberculosis fighting agents

(2013) Edjane R. dos Santos et al.   POLYHEDRON

Activity of IQG-607, a new orally active compound, in a murine model of Mycobacterium tuberculosis infection

(2012) Valnês S. Rodrigues-Junior et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Ruthenium(II) phosphine/diimine/picolinate complexes: Inorganic compounds as agents against tuberculosis

(2011) Fernando R. Pavan et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis, Characterization, and Reactivity of the Stable Iron Carbonyl Complex [Fe(CO)(N4Py)](ClO4)2: Photoactivated Carbon Monoxide Release, Growth Inhibitory Activity, and Peptide Ligation

(2011) Casey S. Jackson et al.   INORGANIC CHEMISTRY

Silicium Dioxide Nanoparticles As Carriers for Photoactivatable CO-Releasing Molecules (PhotoCORMs)

(2011) Gregor Dördelmann et al.   INORGANIC CHEMISTRY

Isoniazid metal complex reactivity and insights for a novel anti-tuberculosis drug design

(2011) Eduardo Henrique Silva Sousa et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Multiwfn: A multifunctional wavefunction analyzer

(2011) Tian Lu et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Tailoring NO Donors Metallopharmaceuticals: Ruthenium Nitrosyl Ammines and Aliphatic Tetraazamacrocycles

(2010) E. Tfouni et al.   CURRENT MEDICINAL CHEMISTRY

Dicarbonyl-bis(cysteamine)iron(II): A light induced carbon monoxide releasing molecule based on iron (CORM-S1)

(2010) Robert Kretschmer et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

The therapeutic potential of carbon monoxide

(2010) Roberto Motterlini et al.   NATURE REVIEWS DRUG DISCOVERY

Eradication of Pathogenic Bacteria by Remote Delivery of NO via Light Triggering of Nitrosyl-Containing Materials

(2010) Genevieve M. Halpenny et al.   ACS Medicinal Chemistry Letters

Targeting proteins with metal complexes

(2009) Eric Meggers   CHEMICAL COMMUNICATIONS

Metal complexes as photochemical nitric oxide precursors: Potential applications in the treatment of tumors

(2009) Alexis D. Ostrowski et al.   DALTON TRANSACTIONS

Driving forces in substitution reactions of octahedral complexes: The influence of the competitive effect

(2009) Eliana M.A. Valle et al.   POLYHEDRON

Photoinduced CO release, cellular uptake and cytotoxicity of a tris(pyrazolyl)methane (tpm) manganese tricarbonyl complex

(2008) Johanna Niesel et al.   CHEMICAL COMMUNICATIONS

Iron(III) complexes withN4-para-tolyl-thiosemicarbazones: spectral and electrochemical studies and toxicity toArtemia salina

(2008) Thays Dos Santos Silva et al.   JOURNAL OF COORDINATION CHEMISTRY

Aggregation and membrane permeabilizing properties of designed histidine-containing cationic linear peptide antibiotics

(2007) Arnaud Marquette et al.   JOURNAL OF PEPTIDE SCIENCE

2-Pyridinoformamide-derived thiosemicarbazones and their iron(III) complexes: Potential antineoplastic activity

(2007) Angelica E. Graminha et al.   POLYHEDRON