Glutamate Dehydrogenase, a Complex Enzyme at a Crucial Metabolic Branch Point

Inhibition of the mitochondrial pyruvate carrier protects from excitotoxic neuronal death

(2017) Ajit S. Divakaruni et al.   JOURNAL OF CELL BIOLOGY

Identification of a Novel Activator of Mammalian Glutamate Dehydrogenase

(2016) Hong Q. Smith et al.   BIOCHEMISTRY

Glutamate oxidation in astrocytes: Roles of glutamate dehydrogenase and aminotransferases

(2016) Mary C. McKenna et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Glutamate dehydrogenase is a novel prognostic marker and predicts metastases in colorectal cancer patients

(2015) Gaojie Liu et al.   Journal of Translational Medicine

Targeting glutamine transport to suppress melanoma cell growth

(2014) Qian Wang et al.   INTERNATIONAL JOURNAL OF CANCER

Determination of Glutamate Dehydrogenase Activity and Its Kinetics in Mouse Tissues using Metabolic Mapping (Quantitative Enzyme Histochemistry)

(2014) Dennis Botman et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Hominoid-specific enzyme GLUD2 promotes growth ofIDH1R132Hglioma

(2014) Ruihuan Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The mTORC1 Pathway Stimulates Glutamine Metabolism and Cell Proliferation by Repressing SIRT4

(2013) Alfred Csibi et al.   CELL

IDH1 and IDH2 Mutations in Tumorigenesis: Mechanistic Insights and Clinical Perspectives

(2012) H. Yang et al.   CLINICAL CANCER RESEARCH

Glutamate dehydrogenase 1 and SIRT4 regulate glial development

(2012) Daniel Komlos et al.   GLIA

The Role of Glutamine Synthetase and Glutamate Dehydrogenase in Cerebral Ammonia Homeostasis

(2012) Arthur J. L. Cooper   NEUROCHEMICAL RESEARCH

Green tea polyphenols in drug discovery: a success or failure?

(2011) Thomas J Smith   Expert Opinion on Drug Discovery

Green Tea Polyphenols Control Dysregulated Glutamate Dehydrogenase in Transgenic Mice by Hijacking the ADP Activation Site

(2011) Changhong Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Basis for Leucine-induced Allosteric Activation of Glutamate Dehydrogenase

(2011) Takeo Tomita et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

β-Cell-protective effect of 2-aminobicyclo-(2,2,1)-heptane-2-carboxylic acid as a glutamate dehydrogenase activator in db/db mice

(2011) Seung Jin Han et al.   JOURNAL OF ENDOCRINOLOGY

The human GLUD2 glutamate dehydrogenase and its regulation in health and disease

(2011) Andreas Plaitakis et al.   NEUROCHEMISTRY INTERNATIONAL

Mechanism of Hyperinsulinism in Short-chain 3-Hydroxyacyl-CoA Dehydrogenase Deficiency Involves Activation of Glutamate Dehydrogenase

(2010) Changhong Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glucose Addiction of TSC Null Cells Is Caused by Failed mTORC1-Dependent Balancing of Metabolic Demand with Supply

(2010) Andrew Y. Choo et al.   MOLECULAR CELL

Human GLUD1 and GLUD2 glutamate dehydrogenase localize to mitochondria and endoplasmic reticulum

(2009) Vasileios Mastorodemos et al.   Biochemistry and Cell Biology

Glioblastoma Cells Require Glutamate Dehydrogenase to Survive Impairments of Glucose Metabolism or Akt Signaling

(2009) C. Yang et al.   CANCER RESEARCH

Novel Inhibitors Complexed with Glutamate Dehydrogenase

(2009) Ming Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transgenic Expression of Glud1 (Glutamate Dehydrogenase 1) in Neurons: In Vivo Model of Enhanced Glutamate Release, Altered Synaptic Plasticity, and Selective Neuronal Vulnerability

(2009) X. Bao et al.   JOURNAL OF NEUROSCIENCE

BCH, an Inhibitor of System L Amino Acid Transporters, Induces Apoptosis in Cancer Cells

(2008) Chun Sung Kim et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

An Integrated Genomic Analysis of Human Glioblastoma Multiforme

(2008) D. W. Parsons et al.   SCIENCE

Untangling the glutamate dehydrogenase allosteric nightmare

(2008) Thomas J. Smith et al.   TRENDS IN BIOCHEMICAL SCIENCES