Adenosine dysfunction in epilepsy

The methylation hypothesis: Do epigenetic chromatin modifications play a role in epileptogenesis?

(2011) Katja Kobow et al.   EPILEPSIA

Upregulation of adenosine kinase in astrocytes in experimental and human temporal lobe epilepsy

(2011) Eleonora Aronica et al.   EPILEPSIA

Adenosine kinase as a target for therapeutic antisense strategies in epilepsy

(2011) Panos Theofilas et al.   EPILEPSIA

Purines and neuronal excitability: Links to the ketogenic diet

(2011) S.A. Masino et al.   EPILEPSY RESEARCH

Local disruption of glial adenosine homeostasis in mice associates with focal electrographic seizures: A first step in epileptogenesis?

(2011) Tianfu Li et al.   GLIA

Adenosine kinase determines the degree of brain injury after ischemic stroke in mice

(2011) Hai-Ying Shen et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

A ketogenic diet suppresses seizures in mice through adenosine A1 receptors

(2011) Susan A. Masino et al.   JOURNAL OF CLINICAL INVESTIGATION

The neurobiology of cognitive disorders in temporal lobe epilepsy

(2011) Brian Bell et al.   Nature Reviews Neurology

International Union of Basic and Clinical Pharmacology. LXXXI. Nomenclature and Classification of Adenosine Receptors--An Update

(2011) B. B. Fredholm et al.   PHARMACOLOGICAL REVIEWS

Integrated Brain Circuits: Astrocytic Networks Modulate Neuronal Activity and Behavior

(2010) Michael M. Halassa et al.   Annual Review of Physiology

Acadesine Inhibits Tissue Factor Induction and Thrombus Formation by Activating the Phosphoinositide 3-Kinase/Akt Signaling Pathway

(2010) Weiyu Zhang et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Glia as a source of cytokines: Implications for neuronal excitability and survival

(2010) Annamaria Vezzani et al.   EPILEPSIA

Manipulation of Adenosine Kinase Affects Sleep Regulation in Mice

(2010) S. Palchykova et al.   JOURNAL OF NEUROSCIENCE

Subcellular localization of adenosine kinase in mammalian cells: The long isoform of AdK is localized in the nucleus

(2009) Xianying Amy Cui et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Adenosine signaling and function in glial cells

(2009) D Boison et al.   CELL DEATH AND DIFFERENTIATION

Antiepileptic effects of silk-polymer based adenosine release in kindled rats

(2009) Cory Szybala et al.   EXPERIMENTAL NEUROLOGY

Can adenosine substitute for SAM-e as an adjunct in the treatment of depression?

(2009) Erik A. Hanson   MEDICAL HYPOTHESES

Ketogenic diets: Evidence for short- and long-term efficacy

(2009) Eric H. Kossoff et al.   Neurotherapeutics

Methionine Metabolism and Liver Disease

(2008) José M. Mato et al.   Annual Review of Nutrition

Silk polymer-based adenosine release: Therapeutic potential for epilepsy

(2008) Andrew Wilz et al.   BIOMATERIALS

A Critical Role of the Adenosine A2A Receptor in Extrastriatal Neurons in Modulating Psychomotor Activity as Revealed by Opposite Phenotypes of Striatum and Forebrain A2A Receptor Knock-Outs

(2008) H.-Y. Shen et al.   JOURNAL OF NEUROSCIENCE

Connexin 43 Hemichannels Are Permeable to ATP

(2008) J. Kang et al.   JOURNAL OF NEUROSCIENCE

The neurobehavioural comorbidities of epilepsy: can a natural history be developed?

(2008) Bruce Hermann et al.   LANCET NEUROLOGY

Adenosine and its receptors: Multiple modulatory functions and potential therapeutic targets for neurologic disease

(2008) E. E. Benarroch   NEUROLOGY

Astrocytic adenosine kinase regulates basal synaptic adenosine levels and seizure activity but not activity-dependent adenosine release in the hippocampus

(2008) Lori-An V. Etherington et al.   NEUROPHARMACOLOGY

Are purines mediators of the anticonvulsant/neuroprotective effects of ketogenic diets?

(2008) Susan A. Masino et al.   TRENDS IN NEUROSCIENCES

Innate and adaptive immunity during epileptogenesis and spontaneous seizures: Evidence from experimental models and human temporal lobe epilepsy

(2007) Teresa Ravizza et al.   NEUROBIOLOGY OF DISEASE

Acute induction of epileptiform discharges by pilocarpine in the in vitro isolated guinea-pig brain requires enhancement of blood–brain barrier permeability

(2007) L. Uva et al.   NEUROSCIENCE

The adenosine kinase hypothesis of epileptogenesis

(2007) Detlev Boison   PROGRESS IN NEUROBIOLOGY

Adenosine in the central nervous system: release mechanisms and extracellular concentrations

(2003) Serena Latini et al.   JOURNAL OF NEUROCHEMISTRY