Betulinic Acid Induces Apoptosis in Differentiated PC12 Cells Via ROS-Mediated Mitochondrial Pathway

Baicalein Induces Caspase-dependent Apoptosis Associated with the Generation of ROS and the Activation of AMPK in Human Lung Carcinoma A549 Cells

(2016) Hong Jae Kim et al.   DRUG DEVELOPMENT RESEARCH

Tunicamycin promotes apoptosis in leukemia cells through ROS generation and downregulation of survivin expression

(2015) Eun Jin Lim et al.   APOPTOSIS

Anti-Influenza Activity of Betulinic Acid from Zizyphus jujuba on Influenza A/PR/8 Virus

(2015) Eun-Hye Hong et al.   Biomolecules & Therapeutics

A novel derivative of betulinic acid, SYK023, suppresses lung cancer growth and malignancy

(2015) Tsung-I Hsu et al.   Oncotarget

Betulinic Acid-Induced Cytotoxicity in Human Breast Tumor Cell Lines MCF-7 and T47D and its Modification by Tocopherol

(2014) Reeta Tiwari et al.   CANCER INVESTIGATION

Induction of apoptosis by isoegomaketone from Perilla frutescens L. in B16 melanoma cells is mediated through ROS generation and mitochondrial-dependent, -independent pathway

(2014) Soon-Jae Kwon et al.   FOOD AND CHEMICAL TOXICOLOGY

Potent anti-inflammatory activity of betulinic acid treatment in a model of lethal endotoxemia

(2014) José Fernando Oliveira Costa et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Mitochondrial electron transport chain is involved in microcystin-RR induced tobacco BY-2 cells apoptosis

(2014) Wenmin Huang et al.   JOURNAL OF ENVIRONMENTAL SCIENCES

NMDA receptor-mediated ERK 1/2 pathway is involved in PFHxS-induced apoptosis of PC12 cells

(2014) Youn Ju Lee et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Betulinic acid regulates generation of neuroinflammatory mediators responsible for tissue destruction in multiple sclerosis in vitro

(2013) Jana Blaževski et al.   ACTA PHARMACOLOGICA SINICA

NADPH Oxidase 1, a Novel Molecular Source of ROS in Hippocampal Neuronal Death in Vascular Dementia

(2013) Dong-Hee Choi et al.   ANTIOXIDANTS & REDOX SIGNALING

Betulinic acid alleviates non-alcoholic fatty liver by inhibiting SREBP1 activity via the AMPK–mTOR–SREBP signaling pathway

(2013) Hai Yan Quan et al.   BIOCHEMICAL PHARMACOLOGY

Induction of apoptosis by antimycin A in differentiated PC12 cell line

(2013) Xu Lanju et al.   JOURNAL OF APPLIED TOXICOLOGY

Evaluation and Optimization of Downstream Process Parameters for Extraction of Betulinic Acid from the Bark ofZiziphus jujubaeL.

(2013) Kashyap Kumar Dubey et al.   TheScientificWorldJOURNAL

Increased betulinic acid induced cytotoxicity and radiosensitivity in glioma cells under hypoxic conditions

(2011) Matthias Bache et al.   Radiation Oncology

Betulinic acid, a natural compound with potent anticancer effects

(2010) Franziska B. Mullauer et al.   ANTI-CANCER DRUGS

Caspase Cascade Regulated Mitochondria Mediated Apoptosis in Monocrotophos Exposed PC12 Cells

(2010) M. P. Kashyap et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Anti-AIDS Agents. 78.†Design, Synthesis, Metabolic Stability Assessment, and Antiviral Evaluation of Novel Betulinic Acid Derivatives as Potent Anti-Human Immunodeficiency Virus (HIV) Agents

(2009) Keduo Qian et al.   JOURNAL OF MEDICINAL CHEMISTRY