Is the blood–brain barrier really disrupted in all glioblastomas? A critical assessment of existing clinical data

Dynamic contrast-enhanced and dynamic susceptibility contrast perfusion MR imaging for glioma grading: Preliminary comparison of vessel compartment and permeability parameters using hotspot and histogram analysis

(2016) Corrado Santarosa et al.   EUROPEAN JOURNAL OF RADIOLOGY

Whole-brain spectroscopic MRI biomarkers identify infiltrating margins in glioblastoma patients

(2016) James S. Cordova et al.   NEURO-ONCOLOGY

The Added Prognostic Value of Preoperative Dynamic Contrast-Enhanced MRI Histogram Analysis in Patients with Glioblastoma: Analysis of Overall and Progression-Free Survival

(2015) Y.S. Choi et al.   AMERICAN JOURNAL OF NEURORADIOLOGY

T1-Weighted Dynamic Contrast-Enhanced MRI as a Noninvasive Biomarker of Epidermal Growth Factor Receptor vIII Status

(2015) J. Arevalo-Perez et al.   AMERICAN JOURNAL OF NEURORADIOLOGY

Insights into brain metastasis in patients with ALK+ lung cancer: is the brain truly a sanctuary?

(2015) Gouji Toyokawa et al.   CANCER AND METASTASIS REVIEWS

Improving drug delivery to primary and metastatic brain tumors: Strategies to overcome the blood-brain barrier

(2015) KE Parrish et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Hypercellularity Components of Glioblastoma Identified by High b-Value Diffusion-Weighted Imaging

(2015) Priyanka P. Pramanik et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Multimodal MRI can identify perfusion and metabolic changes in the invasive margin of glioblastomas

(2015) Stephen J. Price et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING

Preclinical impact of bevacizumab on brain and tumor distribution of irinotecan and temozolomide

(2015) Lauriane Goldwirt et al.   JOURNAL OF NEURO-ONCOLOGY

Strategies to improve delivery of anticancer drugs across the blood–brain barrier to treat glioblastoma

(2015) Rajneet K. Oberoi et al.   NEURO-ONCOLOGY

Multi-Parametric MRI and Texture Analysis to Visualize Spatial Histologic Heterogeneity and Tumor Extent in Glioblastoma

(2015) Leland S. Hu et al.   PLoS One

An Electrically Tight In Vitro Blood–Brain Barrier Model Displays Net Brain-to-Blood Efflux of Substrates for the ABC Transporters, P-gp, Bcrp and Mrp-1

(2014) Hans Christian Helms et al.   AAPS Journal

Prophylactic cranial irradiation for patients with small-cell lung cancer: a systematic review of the literature with meta-analysis

(2014) Wenwen Zhang et al.   BMC CANCER

Complete clinical regression of a BRAF V600E-mutant pediatric glioblastoma multiforme after BRAF inhibitor therapy

(2014) Giles W Robinson et al.   BMC CANCER

Single-agent bevacizumab or lomustine versus a combination of bevacizumab plus lomustine in patients with recurrent glioblastoma (BELOB trial): a randomised controlled phase 2 trial

(2014) Walter Taal et al.   LANCET ONCOLOGY

Report of the Jumpstarting Brain Tumor Drug Development Coalition and FDA clinical trials neuroimaging endpoint workshop (January 30, 2014, Bethesda MD)

(2014) Patrick Y. Wen et al.   NEURO-ONCOLOGY

Precise ex vivo histological validation of heightened cellularity and diffusion-restricted necrosis in regions of dark apparent diffusion coefficient in 7 cases of high-grade glioma

(2014) Peter S. LaViolette et al.   NEURO-ONCOLOGY

A Randomized Trial of Bevacizumab for Newly Diagnosed Glioblastoma

(2014) Mark R. Gilbert et al.   NEW ENGLAND JOURNAL OF MEDICINE

An Intra-Individual Comparison of MRI, [18F]-FET and [18F]-FLT PET in Patients with High-Grade Gliomas

(2014) Martha Nowosielski et al.   PLoS One

Prophylactic Cranial Irradiation May Impose a Detrimental Effect on Overall Survival of Patients with Nonsmall Cell Lung Cancer: A Systematic Review and Meta-Analysis

(2014) Shuan-shuan Xie et al.   PLoS One

Patient-Specific Metrics of Invasiveness Reveal Significant Prognostic Benefit of Resection in a Predictable Subset of Gliomas

(2014) Anne L. Baldock et al.   PLoS One

Patterns of failure for glioblastoma multiforme following limited-margin radiation and concurrent temozolomide

(2014) Brian J Gebhardt et al.   Radiation Oncology

Differential role of P-glycoprotein and breast cancer resistance protein in drug distribution into brain, CSF and peripheral nerve tissues in rats

(2014) Liyue Huang et al.   XENOBIOTICA

Biopsy validation of 18F-DOPA PET and biodistribution in gliomas for neurosurgical planning and radiotherapy target delineation: results of a prospective pilot study

(2013) D. H. Pafundi et al.   NEURO-ONCOLOGY

Integration method of 3D MR spectroscopy into treatment planning system for glioblastoma IMRT dose painting with integrated simultaneous boost

(2013) Soléakhéna Ken et al.   Radiation Oncology

AVAglio: Phase 3 trial of bevacizumab plus temozolomide and radiotherapy in newly diagnosed glioblastoma multiforme

(2011) O. L. Chinot et al.   ADVANCES IN THERAPY

Delivery of molecularly targeted therapy to malignant glioma, a disease of the whole brain

(2011) Sagar Agarwal et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Tissue concentration of systemically administered antineoplastic agents in human brain tumors

(2011) Marshall W. Pitz et al.   JOURNAL OF NEURO-ONCOLOGY

Cilengitide in patients with recurrent glioblastoma: the results of NABTC 03-02, a phase II trial with measures of treatment delivery

(2011) Mark R. Gilbert et al.   JOURNAL OF NEURO-ONCOLOGY

Awake surgery for WHO Grade II gliomas within “noneloquent” areas in the left dominant hemisphere: toward a “supratotal” resection

(2011) Yordanka N. Yordanova et al.   JOURNAL OF NEUROSURGERY

A phase II trial of erlotinib in patients with recurrent malignant gliomas and nonprogressive glioblastoma multiforme postradiation therapy

(2011) J. J. Raizer et al.   NEURO-ONCOLOGY

Relevance of T2 signal changes in the assessment of progression of glioblastoma according to the Response Assessment in Neurooncology criteria

(2011) A. Radbruch et al.   NEURO-ONCOLOGY

Looking at the blood–brain barrier: Molecular anatomy and possible investigation approaches

(2010) Filipa Lourenço Cardoso et al.   BRAIN RESEARCH REVIEWS

Impact of [11C]Methionine Positron Emission Tomography for Target Definition of Glioblastoma Multiforme in Radiation Therapy Planning

(2010) Masayuki Matsuo et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Biopsy Targeting Gliomas

(2010) Marc-André Weber et al.   INVESTIGATIVE RADIOLOGY

Kinetic Analysis of the Cooperation of P-Glycoprotein (P-gp/Abcb1) and Breast Cancer Resistance Protein (Bcrp/Abcg2) in Limiting the Brain and Testis Penetration of Erlotinib, Flavopiridol, and Mitoxantrone

(2010) H. Kodaira et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Patterns of failure and comparison of different target volume delineations in patients with glioblastoma treated with conformal radiotherapy plus concomitant and adjuvant temozolomide

(2010) Giuseppe Minniti et al.   RADIOTHERAPY AND ONCOLOGY

Extracellular fluid concentrations of cisplatin, carboplatin, and oxaliplatin in brain, muscle, and blood measured using microdialysis in nonhuman primates

(2009) Shana Jacobs et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

The Neuropharmacokinetics of Temozolomide in Patients with Resectable Brain Tumors: Potential Implications for the Current Approach to Chemoradiation

(2009) J. Portnow et al.   CLINICAL CANCER RESEARCH

Recurrence Pattern After Temozolomide Concomitant With and Adjuvant to Radiotherapy in Newly Diagnosed Patients With Glioblastoma: Correlation WithMGMTPromoter Methylation Status

(2009) Alba A. Brandes et al.   JOURNAL OF CLINICAL ONCOLOGY

Intratumoral concentrations of imatinib after oral administration in patients with glioblastoma multiforme

(2009) Matthias Holdhoff et al.   JOURNAL OF NEURO-ONCOLOGY

EXTENT OF RESECTION AND SURVIVAL IN GLIOBLASTOMA MULTIFORME

(2009) et al.   NEUROSURGERY

Treating Childhood Acute Lymphoblastic Leukemia without Cranial Irradiation

(2009) Ching-Hon Pui et al.   NEW ENGLAND JOURNAL OF MEDICINE

Effect of blood brain barrier permeability in recurrent high grade gliomas on the intratumoral pharmacokinetics of methotrexate: a microdialysis study

(2008) Jaishri O. Blakeley et al.   JOURNAL OF NEURO-ONCOLOGY

Current management and challenges of malignant disease in the CNS in paediatric leukaemia

(2008) Ching-Hon Pui et al.   LANCET ONCOLOGY

GLIOMA EXTENT OF RESECTION AND ITS IMPACT ON PATIENT OUTCOME

(2008) Nader Sanai et al.   NEUROSURGERY