Microfluidics for sperm analysis and selection

Improved bovine embryo production in an oviduct-on-a-chip system: prevention of poly-spermic fertilization and parthenogenic activation

(2017) Marcia A. M. M. Ferraz et al.   LAB ON A CHIP

Semen quality in the 21st century

(2017) Helena E. Virtanen et al.   Nature Reviews Urology

Coarse-Graining the Fluid Flow around a Human Sperm

(2017) Kenta Ishimoto et al.   PHYSICAL REVIEW LETTERS

An automated smartphone-based diagnostic assay for point-of-care semen analysis

(2017) Manoj Kumar Kanakasabapathy et al.   Science Translational Medicine

A microfluidic culture model of the human reproductive tract and 28-day menstrual cycle

(2017) Shuo Xiao et al.   Nature Communications

Small but Perfectly Formed? Successes, Challenges, and Opportunities for Microfluidics in the Chemical and Biological Sciences

(2017) Daniel T. Chiu et al.   Chem

Relationship between Porcine Sperm Motility and Sperm Enzymatic Activity using Paper-based Devices

(2017) Koji Matsuura et al.   Scientific Reports

Paper-based sperm DNA integrity analysis

(2016) Reza Nosrati et al.   Analytical Methods

Designing 3-Dimensional In Vitro Oviduct Culture Systems to Study Mammalian Fertilization and Embryo Production

(2016) Marcia A. M. M. Ferraz et al.   ANNALS OF BIOMEDICAL ENGINEERING

Lensless Imaging and Sensing

(2016) Aydogan Ozcan et al.   Annual Review of Biomedical Engineering

Bacterial Hydrodynamics

(2016) Eric Lauga   Annual Review of Fluid Mechanics

Sperm processing for advanced reproductive technologies: Where are we today?

(2016) Kari L. Rappa et al.   BIOTECHNOLOGY ADVANCES

Paper-Based Quantification of Male Fertility Potential

(2016) R. Nosrati et al.   CLINICAL CHEMISTRY

Toward a Microfluidics-Based Home Male Fertility Test

(2016) T. W. Guo et al.   CLINICAL CHEMISTRY

Spermometer: electrical characterization of single boar sperm motility

(2016) Bjorn de Wagenaar et al.   FERTILITY AND STERILITY

Influence of increasing body mass index on semen and reproductive hormonal parameters in a multi-institutional cohort of subfertile men

(2016) Jared M. Bieniek et al.   FERTILITY AND STERILITY

Separation efficiency of a microfluidic sperm sorter to minimize sperm DNA damage

(2016) Kyoko Shirota et al.   FERTILITY AND STERILITY

International Committee for Monitoring Assisted Reproductive Technologies world report: Assisted Reproductive Technology 2008, 2009 and 2010

(2016) S. Dyer et al.   HUMAN REPRODUCTION

Semen quality of young adult ICSI offspring: the first results

(2016) F. Belva et al.   HUMAN REPRODUCTION

The total pregnancy potential per oocyte aspiration after assisted reproduction—in how many cycles are biologically competent oocytes available?

(2016) J. G. Lemmen et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Sperm chemotaxis promotes individual fertilization success in sea urchins

(2016) Yasmeen H. Hussain et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Towards microfluidic sperm refinement: impedance-based analysis and sorting of sperm cells

(2016) B. de Wagenaar et al.   LAB ON A CHIP

Turning the corner in fertility: high DNA integrity of boundary-following sperm

(2016) Lise Eamer et al.   LAB ON A CHIP

Male Reproductive Disorders and Fertility Trends: Influences of Environment and Genetic Susceptibility

(2016) Niels E. Skakkebaek et al.   PHYSIOLOGICAL REVIEWS

Unconventional methods of imaging: computational microscopy and compact implementations

(2016) Euan McLeod et al.   REPORTS ON PROGRESS IN PHYSICS

Application of failure mode and effect analysis in an assisted reproduction technology laboratory

(2016) Giulia Intra et al.   REPRODUCTIVE BIOMEDICINE ONLINE

Maternal and Live-birth Outcomes of Pregnancies following Assisted Reproductive Technology: A Retrospective Cohort Study

(2016) Linling Zhu et al.   Scientific Reports

Decline in sperm count and motility in young adult men from 2003 to 2013: observations from a U.S. sperm bank

(2016) G. M. Centola et al.   Andrology

Assisted Reproductive Technology and Birth Defects Among Liveborn Infants in Florida, Massachusetts, and Michigan, 2000-2010

(2016) Sheree L. Boulet et al.   JAMA Pediatrics

Human sperm rheotaxis: a passive physical process

(2016) Zhuoran Zhang et al.   Scientific Reports

Predominance of sperm motion in corners

(2016) Reza Nosrati et al.   Scientific Reports

Systematic characterization of seminal plasma piRNAs as molecular biomarkers for male infertility

(2016) Yeting Hong et al.   Scientific Reports

Microfluidic assessment of swimming media for motility-based sperm selection

(2015) Lise Eamer et al.   Biomicrofluidics

Disrupting the wall accumulation of human sperm cells by artificial corrugation

(2015) H. A. Guidobaldi et al.   Biomicrofluidics

Mammalian sperm interactions with the female reproductive tract

(2015) Susan S. Suarez   CELL AND TISSUE RESEARCH

Total motile sperm count: a better indicator for the severity of male factor infertility than the WHO sperm classification system

(2015) J. A. M. Hamilton et al.   HUMAN REPRODUCTION

Sperm selection in natural conception: what can we learn from Mother Nature to improve assisted reproduction outcomes?

(2015) Denny Sakkas et al.   HUMAN REPRODUCTION UPDATE

Recent microfluidic devices for studying gamete and embryo biomechanics

(2015) David Lai et al.   JOURNAL OF BIOMECHANICS

Direct DNA Analysis with Paper-Based Ion Concentration Polarization

(2015) Max M. Gong et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Fluid flow and sperm guidance: a simulation study of hydrodynamic sperm rheotaxis

(2015) K. Ishimoto et al.   Journal of the Royal Society Interface

Microfluidic single sperm entrapment and analysis

(2015) B. de Wagenaar et al.   LAB ON A CHIP

Cellular Cargo Delivery: Toward Assisted Fertilization by Sperm-Carrying Micromotors

(2015) Mariana Medina-Sánchez et al.   NANO LETTERS

Just keep swimming — sperm exhibit a 2D slither motion

(2015) Louise Stone   Nature Reviews Urology

Hydrodynamic analysis of flagellated bacteria swimming in corners of rectangular channels

(2015) Henry Shum et al.   PHYSICAL REVIEW E

Emergence of Upstream Swimming via a Hydrodynamic Transition

(2015) Chih-kuan Tung et al.   PHYSICAL REVIEW LETTERS

Microgrooves and fluid flows provide preferential passageways for sperm over pathogenTritrichomonas foetus

(2015) Chih-kuan Tung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bimodal rheotactic behavior reflects flagellar beat asymmetry in human sperm cells

(2015) Anton Bukatin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Physics of microswimmers—single particle motion and collective behavior: a review

(2015) J Elgeti et al.   REPORTS ON PROGRESS IN PHYSICS

The relationship between sperm viability and DNA fragmentation rates

(2015) Mary K Samplaski et al.   Reproductive Biology and Endocrinology

A unique view on male infertility around the globe

(2015) Ashok Agarwal et al.   Reproductive Biology and Endocrinology

Analyzing IVF laboratory error rates: highlight or hide?

(2015) D. Sakkas et al.   REPRODUCTIVE BIOMEDICINE ONLINE

Development of computer-assisted sperm analysis plugin for analyzing sperm motion in microfluidic environments using Image-J

(2015) Mohamed Elsayed et al.   THERIOGENOLOGY

Microfluidics for sperm research

(2015) Stephanie M. Knowlton et al.   TRENDS IN BIOTECHNOLOGY

Two-dimensional slither swimming of sperm within a micrometre of a surface

(2015) Reza Nosrati et al.   Nature Communications

Sperm navigation along helical paths in 3D chemoattractant landscapes

(2015) Jan F. Jikeli et al.   Nature Communications

Generation of Gradients on a Microfluidic Device: Toward a High-Throughput Investigation of Spermatozoa Chemotaxis

(2015) Yi Zhang et al.   PLoS One

Imaging and Sizing of Single DNA Molecules on a Mobile Phone

(2014) Qingshan Wei et al.   ACS Nano

Characterization of rheotaxis of bull sperm using microfluidics

(2014) Taymour M. El-Sherry et al.   Integrative Biology

Holographic imaging of unlabelled sperm cells for semen analysis: a review

(2014) Giuseppe Di Caprio et al.   Journal of Biophotonics

Cooperative roles of biological flow and surface topography in guiding sperm migration revealed by a microfluidic model

(2014) Chih-kuan Tung et al.   LAB ON A CHIP

Make it spin: individual trapping of sperm for analysis and recovery using micro-contact printing

(2014) J.-P. Frimat et al.   LAB ON A CHIP

Rare cell isolation and analysis in microfluidics

(2014) Yuchao Chen et al.   LAB ON A CHIP

Rapid selection of sperm with high DNA integrity

(2014) Reza Nosrati et al.   LAB ON A CHIP

The study of spermatozoa and sorting in relation to human reproduction

(2014) James Boon Yong Koh et al.   Microfluidics and Nanofluidics

Paper-based diagnostic devices for evaluating the quality of human sperm

(2014) Koji Matsuura et al.   Microfluidics and Nanofluidics

The present and future role of microfluidics in biomedical research

(2014) Eric K. Sackmann et al.   NATURE

Structural mechanism of the dynein power stroke

(2014) Jianfeng Lin et al.   NATURE CELL BIOLOGY

Microfluidic, marker-free isolation of circulating tumor cells from blood samples

(2014) Nezihi Murat Karabacak et al.   Nature Protocols

Male infertility: a public health issue caused by sexually transmitted pathogens

(2014) Fabrícia Gimenes et al.   Nature Reviews Urology

Seminal plasma as a diagnostic fluid for male reproductive system disorders

(2014) Andrei P. Drabovich et al.   Nature Reviews Urology

Review of digital holographic microscopy for three-dimensional profiling and tracking

(2014) Xiao Yu et al.   OPTICAL ENGINEERING

Geometrical guidance and trapping transition of human sperm cells

(2014) A. Guidobaldi et al.   PHYSICAL REVIEW E

Sperm Dynamics in Tubular Confinement

(2014) Veronika Magdanz et al.   Small

Commercialization of microfluidic devices

(2014) Lisa R. Volpatti et al.   TRENDS IN BIOTECHNOLOGY

Selection of Functional Human Sperm with Higher DNA Integrity and Fewer Reactive Oxygen Species

(2014) Waseem Asghar et al.   Advanced Healthcare Materials

Flagellar synchronization through direct hydrodynamic interactions

(2014) Douglas R Brumley et al.   eLife

Sperm quality assessment via separation and sedimentation in a microfluidic device

(2013) Chang-Yu Chen et al.   ANALYST

Prolonged incubation of processed human spermatozoa will increase DNA fragmentation

(2013) A. Nabi et al.   ANDROLOGIA

Direct Characterization of Motion-Dependent Parameters of Sperm in a Microfluidic Device: Proof of Principle

(2013) Y.-A. Chen et al.   CLINICAL CHEMISTRY

Mobile Device for Disease Diagnosis and Data Tracking in Resource-Limited Settings

(2013) C. D. Chin et al.   CLINICAL CHEMISTRY

Rheotaxis Guides Mammalian Sperm

(2013) Kiyoshi Miki et al.   CURRENT BIOLOGY

Novel technologies for selecting the best sperm for in vitro fertilization and intracytoplasmic sperm injection

(2013) Denny Sakkas   FERTILITY AND STERILITY

Digital holography as a method for 3D imaging and estimating the biovolume of motile cells

(2013) F. Merola et al.   LAB ON A CHIP

Paper-based microfluidic point-of-care diagnostic devices

(2013) Ali Kemal Yetisen et al.   LAB ON A CHIP

Different Migration Patterns of Sea Urchin and Mouse Sperm Revealed by a Microfluidic Chemotaxis Device

(2013) Haixin Chang et al.   PLoS One

Ciliary contact interactions dominate surface scattering of swimming eukaryotes

(2013) Vasily Kantsler et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Differential Diagnosis of Azoospermia with Proteomic Biomarkers ECM1 and TEX101 Quantified in Seminal Plasma

(2013) A. P. Drabovich et al.   Science Translational Medicine

Exhaustion of Racing Sperm in Nature-Mimicking Microfluidic Channels During Sorting

(2013) Savas Tasoglu et al.   Small

Computer-assisted sperm analysis (CASA): Capabilities and potential developments

(2013) Rupert P. Amann et al.   THERIOGENOLOGY

The computational sperm cell

(2013) Luis Alvarez et al.   TRENDS IN CELL BIOLOGY

Semen Assessment

(2013) Grace M. Centola   UROLOGIC CLINICS OF NORTH AMERICA

Sperm Trajectories Form Chiral Ribbons

(2013) Ting-Wei Su et al.   Scientific Reports

Decline of semen quality among 10 932 males consulting for couple infertility over a 20-year period in Marseille, France

(2012) Cendrine Geoffroy-Siraudin et al.   ASIAN JOURNAL OF ANDROLOGY

Sperm cells manipulation employing dielectrophoresis

(2012) E. Rosales-Cruzaley et al.   BIOPROCESS AND BIOSYSTEMS ENGINEERING

Semen analysis: looking for an upgrade in class

(2012) Christopher De Jonge   FERTILITY AND STERILITY

Estimating the prevalence of infertility in Canada

(2012) T. Bushnik et al.   HUMAN REPRODUCTION

Lab-on-a-chip biophotonics: its application to assisted reproductive technologies

(2012) David Lai et al.   Journal of Biophotonics

Engineers are from PDMS-land, Biologists are from Polystyrenia

(2012) Erwin Berthier et al.   LAB ON A CHIP

Imaging without lenses: achievements and remaining challenges of wide-field on-chip microscopy

(2012) Alon Greenbaum et al.   NATURE METHODS

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Semen quality, sperm selection and hematospermia

(2012) Amichai Kilchevsky et al.   Nature Reviews Urology

Reproductive Technologies and the Risk of Birth Defects

(2012) Michael J. Davies et al.   NEW ENGLAND JOURNAL OF MEDICINE

Human spermatozoa migration in microchannels reveals boundary-following navigation

(2012) P. Denissenko et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High-throughput lensfree 3D tracking of human sperms reveals rare statistics of helical trajectories

(2012) T.-W. Su et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In Vitro Fertilization on a Single-Oocyte Positioning System Integrated with Motile Sperm Selection and Early Embryo Development

(2011) Rui Ma et al.   ANALYTICAL CHEMISTRY

Microfluidics for Mammalian Cell Chemotaxis

(2011) Beum Jun Kim et al.   ANNALS OF BIOMEDICAL ENGINEERING

Mammalian Sperm Motility: Observation and Theory

(2011) E.A. Gaffney et al.   Annual Review of Fluid Mechanics

Comparison of four methods to evaluate sperm DNA integrity between mouse caput and cauda epididymidis

(2011) Serafín Pérez-Cerezales et al.   ASIAN JOURNAL OF ANDROLOGY

Semen analysis and sperm function testing

(2011) Daniel R Franken et al.   ASIAN JOURNAL OF ANDROLOGY

Response to Comment on Article: Hydrodynamics of Sperm Cells Near Surfaces

(2011) Jens Elgeti et al.   BIOPHYSICAL JOURNAL

Comment on the Article by J. Elgeti, U. B. Kaupp, and G. Gompper: Hydrodynamics of Sperm Cells Near Surfaces

(2011) D.J. Smith et al.   BIOPHYSICAL JOURNAL

At home testing: optimizing management for the infertility physician

(2011) Paul R. Brezina et al.   FERTILITY AND STERILITY

Final ART success rates: a 10 years survey

(2011) C. Gnoth et al.   HUMAN REPRODUCTION

Effects of advanced selection methods on sperm quality and ART outcome: a systematic review

(2011) Tamer M. Said et al.   HUMAN REPRODUCTION UPDATE

Virtual Azoospermia and Cryptozoospermia--Fresh/Frozen Testicular or Ejaculate Sperm for Better IVF Outcome?

(2011) R. Hauser et al.   JOURNAL OF ANDROLOGY

Synchronization of flexible sheets

(2011) GWYNN J. ELFRING et al.   JOURNAL OF FLUID MECHANICS

Lensless imaging for simultaneous microfluidic sperm monitoring and sorting

(2011) Xiaohui Zhang et al.   LAB ON A CHIP

Strategies for locating the female gamete: the importance of measuring sperm trajectories in three spatial dimensions

(2011) A. Guerrero et al.   MOLECULAR HUMAN REPRODUCTION

Sperm motility: is viscosity fundamental to progress?

(2011) J. C. Kirkman-Brown et al.   MOLECULAR HUMAN REPRODUCTION

Sperm flagella: comparative and phylogenetic perspectives of protein components

(2011) K. Inaba   MOLECULAR HUMAN REPRODUCTION

Progesterone activates the principal Ca2+ channel of human sperm

(2011) Polina V. Lishko et al.   NATURE

Dendritic cell chemotaxis in 3D under defined chemokine gradients reveals differential response to ligands CCL21 and CCL19

(2011) U. Haessler et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fluid dynamics and noise in bacterial cell-cell and cell-surface scattering

(2011) K. Drescher et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Preparation and incubation conditions affect the DNA integrity of ejaculated human spermatozoa

(2010) Rieko Matsuura et al.   ASIAN JOURNAL OF ANDROLOGY

Hydrodynamics of Sperm Cells near Surfaces

(2010) Jens Elgeti et al.   BIOPHYSICAL JOURNAL

Integration of Sperm Motility and Chemotaxis Screening with a Microchannel-Based Device

(2010) L. Xie et al.   CLINICAL CHEMISTRY

Effects of semen storage and separation techniques on sperm DNA fragmentation

(2010) Robert E. Jackson et al.   FERTILITY AND STERILITY

SpermCheck® Fertility, an immunodiagnostic home test that detects normozoospermia and severe oligozoospermia

(2010) M.A. Coppola et al.   HUMAN REPRODUCTION

Quantitative Label-Free Animal Sperm Imaging by Means of Digital Holographic Microscopy

(2010) G Di Caprio et al.   IEEE JOURNAL OF SELECTED TOPICS IN QUANTUM ELECTRONICS

Flagellar and ciliary beating: the proven and the possible

(2010) C. B. Lindemann et al.   JOURNAL OF CELL SCIENCE

High-precision tracking of sperm swimming fine structure provides strong test of resistive force theory

(2010) B. M. Friedrich et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Two-dimensional flagellar synchronization in viscoelastic fluids

(2010) GWYNN J. ELFRING et al.   JOURNAL OF FLUID MECHANICS

Nonlinear instability in flagellar dynamics: a novel modulation mechanism in sperm migration?

(2010) H. Gadelha et al.   Journal of the Royal Society Interface

A Noninvasive, Motility Independent, Sperm Sorting Method and Technology to Identify and Retrieve Individual Viable Nonmotile Sperm for Intracytoplasmic Sperm Injection

(2010) Maurice M. Garcia et al.   JOURNAL OF UROLOGY

On-chip determination of spermatozoa concentration using electrical impedance measurements

(2010) Loes I. Segerink et al.   LAB ON A CHIP

Motile and non-motile sperm diagnostic manipulation using optoelectronic tweezers

(2010) Aaron T. Ohta et al.   LAB ON A CHIP

Analysis of sperm concentration and motility in a microfluidic device

(2010) Yu-An Chen et al.   Microfluidics and Nanofluidics

The effect of obesity on sperm disorders and male infertility

(2010) Stefan S. Du Plessis et al.   Nature Reviews Urology

Viscoelastic Fluid Response Can Increase the Speed and Efficiency of a Free Swimmer

(2010) Joseph Teran et al.   PHYSICAL REVIEW LETTERS

Modelling bacterial behaviour close to a no-slip plane boundary: the influence of bacterial geometry

(2010) H. Shum et al.   PROCEEDINGS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES

Life around the scallop theorem

(2010) Eric Lauga   Soft Matter

Diagnostics for the Developing World: Microfluidic Paper-Based Analytical Devices

(2009) Andres W. Martinez et al.   ANALYTICAL CHEMISTRY

An agarose-based microfluidic platform with a gradient buffer for 3D chemotaxis studies

(2009) Ulrike Haessler et al.   BIOMEDICAL MICRODEVICES

World Health Organization reference values for human semen characteristics*‡

(2009) Trevor G. Cooper et al.   HUMAN REPRODUCTION UPDATE

A study of synchronisation between the flagella of bull spermatozoa, with related observations

(2009) D. M. Woolley et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Human sperm accumulation near surfaces: a simulation study

(2009) D. J. SMITH et al.   JOURNAL OF FLUID MECHANICS

Is there a problem with male reproduction?

(2009) Ulla Nordström Joensen et al.   Nature Reviews Endocrinology

Cumulative Live-Birth Rates after In Vitro Fertilization

(2009) Beth A. Malizia et al.   NEW ENGLAND JOURNAL OF MEDICINE

Swimming speeds of filaments in nonlinearly viscoelastic fluids

(2009) Henry C. Fu et al.   PHYSICS OF FLUIDS

The hydrodynamics of swimming microorganisms

(2009) Eric Lauga et al.   REPORTS ON PROGRESS IN PHYSICS

Bend propagation in the flagella of migrating human sperm, and its modulation by viscosity

(2009) D. J. Smith et al.   CELL MOTILITY AND THE CYTOSKELETON

Localized prostate cancer: can we better define who is at risk of unfavourable outcome?

(2008) Steven Joniau et al.   BJU INTERNATIONAL

Infertility and the provision of infertility medical services in developing countries

(2008) W. Ombelet et al.   HUMAN REPRODUCTION UPDATE

Clinical and Consumer Trial Performance of a Sensitive Immunodiagnostic Home Test That Qualitatively Detects Low Concentrations of Sperm Following Vasectomy

(2008) Kenneth L. Klotz et al.   JOURNAL OF UROLOGY

Using ratchets and sorters to fractionate motile cells of Escherichia coli by length

(2008) S. Elizabeth Hulme et al.   LAB ON A CHIP

The biology of infertility: research advances and clinical challenges

(2008) Martin M Matzuk et al.   NATURE MEDICINE

Cooperation of sperm in two dimensions: Synchronization, attraction, and aggregation through hydrodynamic interactions

(2008) Yingzi Yang et al.   PHYSICAL REVIEW E

Hydrodynamic Attraction of Swimming Microorganisms by Surfaces

(2008) Allison P. Berke et al.   PHYSICAL REVIEW LETTERS