Total chemical synthesis of histones and their analogs, assisted by native chemical ligation and palladium complexes

Efficient Palladium-Assisted One-Pot Deprotection of (Acetamidomethyl)Cysteine Following Native Chemical Ligation and/or Desulfurization To Expedite Chemical Protein Synthesis

(2016) Suman Kumar Maity et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chemical Synthesis of Phosphorylated Histone H2A at Tyr57 Reveals Insight into the Inhibition Mode of the SAGA Deubiquitinating Module

(2016) Muhammad Jbara et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Traceless Synthesis of Asymmetrically Modified Bivalent Nucleosomes

(2016) Carolin C. Lechner et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium-Assisted Cleavage of Peptides and Proteins Containing a Backbone with Thiazolidine Linkage

(2016) Muhammad Jbara et al.   CHEMISTRY-A EUROPEAN JOURNAL

Chemical and semisynthesis of modified histones

(2016) Suman Kumar Maity et al.   JOURNAL OF PEPTIDE SCIENCE

Palladium Mediated Rapid Deprotection of N-Terminal Cysteine under Native Chemical Ligation Conditions for the Efficient Preparation of Synthetically Challenging Proteins

(2016) Muhammad Jbara et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Expanding the chemical toolbox for the synthesis of large and uniquely modified proteins

(2016) Somasekhar Bondalapati et al.   Nature Chemistry

Protein chemical synthesis by α-ketoacid–hydroxylamine ligation

(2016) Thibault J Harmand et al.   Nature Protocols

Palladium-Assisted Removal of a Solubilizing Tag from a Cys Side Chain To Facilitate Peptide and Protein Synthesis

(2016) Suman Kumar Maity et al.   ORGANIC LETTERS

Structural basis for histone H2B deubiquitination by the SAGA DUB module

(2016) M. T. Morgan et al.   SCIENCE

Convergent Versus Sequential Protein Synthesis: The Case of Ubiquitinated and Glycosylated H2B

(2015) Mallikanti Seenaiah et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Application of the Protein Semisynthesis Strategy to the Generation of Modified Chromatin

(2015) Matthew Holt et al.   Annual Review of Biochemistry

Chemical tagging and customizing of cellular chromatin states using ultrafast trans-splicing inteins

(2015) Yael David et al.   Nature Chemistry

Histones: At the Crossroads of Peptide and Protein Chemistry

(2014) Manuel M. Müller et al.   CHEMICAL REVIEWS

Chemical synthesis and biophysical applications of membrane proteins

(2014) Chao Zuo et al.   JOURNAL OF PEPTIDE SCIENCE

Tyrosine phosphorylation of histone H2A by CK2 regulates transcriptional elongation

(2014) Harihar Basnet et al.   NATURE

Every amino acid matters: essential contributions of histone variants to mammalian development and disease

(2014) Ian Maze et al.   NATURE REVIEWS GENETICS

One-pot native chemical ligation of peptide hydrazides enables total synthesis of modified histones

(2014) Jiabin Li et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Selective chemical protein modification

(2014) Christopher D. Spicer et al.   Nature Communications

Convergent Chemical Synthesis of Histone H2B Protein for the Site-Specific Ubiquitination at Lys34

(2013) Peter Siman et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chemical synthesis of proteins using peptide hydrazides as thioester surrogates

(2013) Ji-Shen Zheng et al.   Nature Protocols

Highly efficient one-pot ligation and desulfurization

(2013) Tal Moyal et al.   Chemical Science

Convergent Chemical Synthesis of Proteins by Ligation of Peptide Hydrazides

(2012) Ge-Min Fang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Regulation of chromatin by histone modifications

(2011) Andrew J Bannister et al.   CELL RESEARCH

Chemical Synthesis and Expression of the HIV-1 Rev Protein

(2011) Peter Siman et al.   CHEMBIOCHEM

The RING Finger Protein MSL2 in the MOF Complex Is an E3 Ubiquitin Ligase for H2B K34 and Is Involved in Crosstalk with H3 K4 and K79 Methylation

(2011) Lipeng Wu et al.   MOLECULAR CELL

Protecting group variations of δ-mercaptolysine useful in chemical ubiquitylation

(2010) Mahmood Haj-Yahya et al.   BIOPOLYMERS

N-Methylcysteine-mediated total chemical synthesis of ubiquitin thioester

(2010) Lesly A. Erlich et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Highly Efficient and Chemoselective Peptide Ubiquitylation

(2009) K. S. Ajish Kumar et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

An Efficient Fmoc-SPPS Approach for the Generation of Thioester Peptide Precursors for Use in Native Chemical Ligation

(2008) Juan B. Blanco-Canosa et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION