Germline Chd8 haploinsufficiency alters brain development in mouse

Hallmarks of Alzheimer’s Disease in Stem-Cell-Derived Human Neurons Transplanted into Mouse Brain

(2017) Ira Espuny-Camacho et al.   NEURON

Chd8 Mutation Leads to Autistic-like Behaviors and Impaired Striatal Circuits

(2017) Randall J. Platt et al.   Cell Reports

Cell-Type-Specific Alternative Splicing Governs Cell Fate in the Developing Cerebral Cortex

(2016) Xiaochang Zhang et al.   CELL

Agenesis of the corpus callosum in Nogo receptor deficient mice

(2016) Seung-Wan Yoo et al.   JOURNAL OF COMPARATIVE NEUROLOGY

A Novel and Multivalent Role of Pax6 in Cerebellar Development

(2016) J. Yeung et al.   JOURNAL OF NEUROSCIENCE

Genome-wide changes in lncRNA, splicing and regional gene expression patterns in autism

(2016) Neelroop N. Parikshak et al.   NATURE

CHD8 haploinsufficiency results in autistic-like phenotypes in mice

(2016) Yuta Katayama et al.   NATURE

Chd8 mediates cortical neurogenesis via transcriptional regulation of cell cycle and Wnt signaling

(2016) Omer Durak et al.   NATURE NEUROSCIENCE

Corticothalamic Projection Neuron Development beyond Subtype Specification: Fog2 and Intersectional Controls Regulate Intraclass Neuronal Diversity

(2016) Maria J. Galazo et al.   NEURON

Cytoplasmic Rbfox1 Regulates the Expression of Synaptic and Autism-Related Genes

(2016) Ji-Ann Lee et al.   NEURON

First glimpses of the neurobiology of autism spectrum disorder

(2015) Stephan J Sanders   CURRENT OPINION IN GENETICS & DEVELOPMENT

Glucose Intolerance in Aging Male IGFBP-3 Transgenic Mice: Differential Effects of Human IGFBP-3 and Its Mutant IGFBP-3 Devoid of IGF Binding Ability

(2015) K. Hoa Nguyen et al.   ENDOCRINOLOGY

16p11.2 Deletion mice display cognitive deficits in touchscreen learning and novelty recognition tasks

(2015) M. Yang et al.   LEARNING & MEMORY

Genetic studies in intellectual disability and related disorders

(2015) Lisenka E. L. M. Vissers et al.   NATURE REVIEWS GENETICS

Insights into Autism Spectrum Disorder Genomic Architecture and Biology from 71 Risk Loci

(2015) Stephan J. Sanders et al.   NEURON

GABAB Receptor Agonist R-Baclofen Reverses Social Deficits and Reduces Repetitive Behavior in Two Mouse Models of Autism

(2015) J L Silverman et al.   NEUROPSYCHOPHARMACOLOGY

Behavioral assessment of NIH Swiss mice acutely intoxicated with tetramethylenedisulfotetramine

(2015) Brenna M. Flannery et al.   NEUROTOXICOLOGY AND TERATOLOGY

RSAT 2015: Regulatory Sequence Analysis Tools

(2015) Alejandra Medina-Rivera et al.   NUCLEIC ACIDS RESEARCH

The autism-associated chromatin modifier CHD8 regulates other autism risk genes during human neurodevelopment

(2015) Justin Cotney et al.   Nature Communications

Full UPF3B function is critical for neuronal differentiation of neural stem cells

(2015) Tahani Alrahbeni et al.   Molecular Brain

Comprehensive Analysis of the 16p11.2 Deletion and Null Cntnap2 Mouse Models of Autism Spectrum Disorder

(2015) Daniela Brunner et al.   PLoS One

Disruptive CHD8 Mutations Define a Subtype of Autism Early in Development

(2014) Raphael Bernier et al.   CELL

The discovery of integrated gene networks for autism and related disorders

(2014) Fereydoun Hormozdiari et al.   GENOME RESEARCH

Development of MRI-based atlases of non-human brains

(2014) Jeremy F.P. Ullmann et al.   JOURNAL OF COMPARATIVE NEUROLOGY

The adipogenic transcriptional cofactor ZNF638 interacts with splicing regulators and influences alternative splicing

(2014) Chen Du et al.   JOURNAL OF LIPID RESEARCH

De novo mutations in schizophrenia implicate chromatin remodeling and support a genetic overlap with autism and intellectual disability

(2014) S E McCarthy et al.   MOLECULAR PSYCHIATRY

Clustering autism: using neuroanatomical differences in 26 mouse models to gain insight into the heterogeneity

(2014) J Ellegood et al.   MOLECULAR PSYCHIATRY

Synaptic, transcriptional and chromatin genes disrupted in autism

(2014) Silvia De Rubeis et al.   NATURE

The contribution of de novo coding mutations to autism spectrum disorder

(2014) Ivan Iossifov et al.   NATURE

CHD8regulates neurodevelopmental pathways associated with autism spectrum disorder in neural progenitors

(2014) Aarathi Sugathan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Loss of Wdfy3 in mice alters cerebral cortical neurogenesis reflecting aspects of the autism pathology

(2014) Lori A. Orosco et al.   Nature Communications

Long-term exposure to intranasal oxytocin in a mouse autism model

(2014) K L Bales et al.   Translational Psychiatry

Genetic Effects on Cerebellar Structure Across Mouse Models of Autism Using a Magnetic Resonance Imaging Atlas

(2013) Patrick E. Steadman et al.   Autism Research

Behavioural methods used in rodent models of autism spectrum disorders: Current standards and new developments

(2013) Markus Wöhr et al.   BEHAVIOURAL BRAIN RESEARCH

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

(2013) Y. Liao et al.   BIOINFORMATICS

Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool

(2013) Edward Y Chen et al.   BMC BIOINFORMATICS

Coexpression Networks Implicate Human Midfetal Deep Cortical Projection Neurons in the Pathogenesis of Autism

(2013) A. Jeremy Willsey et al.   CELL

Integrative Functional Genomic Analyses Implicate Specific Molecular Pathways and Circuits in Autism

(2013) Neelroop N. Parikshak et al.   CELL

Rapid and Pervasive Changes in Genome-wide Enhancer Usage during Mammalian Development

(2013) Alex S. Nord et al.   CELL

Chromatin modifiers and remodellers: regulators of cellular differentiation

(2013) Taiping Chen et al.   NATURE REVIEWS GENETICS

From neural development to cognition: unexpected roles for chromatin

(2013) Jehnna L. Ronan et al.   NATURE REVIEWS GENETICS

The Reactome pathway knowledgebase

(2013) David Croft et al.   NUCLEIC ACIDS RESEARCH

RNA-Guided Human Genome Engineering via Cas9

(2013) P. Mali et al.   SCIENCE

RSeQC: quality control of RNA-seq experiments

(2012) Liguo Wang et al.   BIOINFORMATICS

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Preparation of fixed mouse brains for MRI

(2012) Lindsay S. Cahill et al.   NEUROIMAGE

Influence of stimulant-induced hyperactivity on social approach in the BTBR mouse model of autism

(2012) Jill L. Silverman et al.   NEUROPHARMACOLOGY

Reversal of Disease-Related Pathologies in the Fragile X Mouse Model by Selective Activation of GABAB Receptors with Arbaclofen

(2012) C. Henderson et al.   Science Translational Medicine

Negative Allosteric Modulation of the mGluR5 Receptor Reduces Repetitive Behaviors and Rescues Social Deficits in Mouse Models of Autism

(2012) J. L. Silverman et al.   Science Translational Medicine

FMRP Stalls Ribosomal Translocation on mRNAs Linked to Synaptic Function and Autism

(2011) Jennifer C. Darnell et al.   CELL

Loss of neural recognition molecule NB-3 delays the normal projection and terminal branching of developing corticospinal tract axons in the mouse

(2011) Zhenhui Huang et al.   JOURNAL OF COMPARATIVE NEUROLOGY

SPARC-like 1 (SC1) is a diversely expressed and developmentally regulated matricellular protein that does not compensate for the absence of SPARC in the CNS

(2011) Samantha Lloyd-Burton et al.   JOURNAL OF COMPARATIVE NEUROLOGY

FMR1 premutation and full mutation molecular mechanisms related to autism

(2011) Randi Hagerman et al.   Journal of Neurodevelopmental Disorders

Transcriptomic analysis of autistic brain reveals convergent molecular pathology

(2011) Irina Voineagu et al.   NATURE

Group I metabotropic glutamate receptor antagonists alter select behaviors in a mouse model for fragile X syndrome

(2011) Alexia M. Thomas et al.   PSYCHOPHARMACOLOGY

Proteins Encoded in Genomic Regions Associated with Immune-Mediated Disease Physically Interact and Suggest Underlying Biology

(2011) Elizabeth J. Rossin et al.   PLoS Genetics

Unusual repertoire of vocalizations in adult BTBR T+tf/J mice during three types of social encounters

(2010) M. L. Scattoni et al.   GENES BRAIN AND BEHAVIOR

Chromatin remodelling during development

(2010) Lena Ho et al.   NATURE

Analysis and design of RNA sequencing experiments for identifying isoform regulation

(2010) Yarden Katz et al.   NATURE METHODS

Behavioural phenotyping assays for mouse models of autism

(2010) Jill L. Silverman et al.   NATURE REVIEWS NEUROSCIENCE

A reproducible evaluation of ANTs similarity metric performance in brain image registration

(2010) Brian B. Avants et al.   NEUROIMAGE

Low stress reactivity and neuroendocrine factors in the BTBR T+tf/J mouse model of autism

(2010) J.L. Silverman et al.   NEUROSCIENCE

Gene ontology analysis for RNA-seq: accounting for selection bias

(2010) Matthew D Young et al.   GENOME BIOLOGY

Fast and accurate short read alignment with Burrows-Wheeler transform

(2009) H. Li et al.   BIOINFORMATICS

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

Mutations of the UPF3B gene, which encodes a protein widely expressed in neurons, are associated with nonspecific mental retardation with or without autism

(2009) F Laumonnier et al.   MOLECULAR PSYCHIATRY

Mouse neurexin-1  deletion causes correlated electrophysiological and behavioral changes consistent with cognitive impairments

(2009) M. R. Etherton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Marble burying reflects a repetitive and perseverative behavior more than novelty-induced anxiety

(2009) Alexia Thomas et al.   PSYCHOPHARMACOLOGY

Minimal aberrant behavioral phenotypes of neuroligin-3 R451C knockin mice

(2008) Kathryn K. Chadman et al.   Autism Research

WGCNA: an R package for weighted correlation network analysis

(2008) Peter Langfelder et al.   BMC BIOINFORMATICS

Cortical thickness measured from MRI in the YAC128 mouse model of Huntington's disease

(2008) Jason P. Lerch et al.   NEUROIMAGE

High resolution three-dimensional brain atlas using an average magnetic resonance image of 40 adult C57Bl/6J mice

(2008) A.E. Dorr et al.   NEUROIMAGE

STRING 8--a global view on proteins and their functional interactions in 630 organisms

(2008) L. J. Jensen et al.   NUCLEIC ACIDS RESEARCH

Symmetric diffeomorphic image registration with cross-correlation: Evaluating automated labeling of elderly and neurodegenerative brain

(2007) B AVANTS et al.   MEDICAL IMAGE ANALYSIS