Real-time visualization of perforin nanopore assembly

Giant MACPF/CDC pore forming toxins: A class of their own

(2016) Cyril F. Reboul et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Atomic force microscopy of membrane pore formation by cholesterol dependent cytolysins

(2016) Adrian W Hodel et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Bax assembly into rings and arcs in apoptotic mitochondria is linked to membrane pores

(2016) R. Salvador-Gallego et al.   EMBO JOURNAL

The membrane attack complex, perforin and cholesterol-dependent cytolysin superfamily of pore-forming proteins

(2016) Natalya Lukoyanova et al.   JOURNAL OF CELL SCIENCE

Structure of the poly-C9 component of the complement membrane attack complex

(2016) Natalya V. Dudkina et al.   Nature Communications

Structural basis of complement membrane attack complex formation

(2016) Marina Serna et al.   Nature Communications

Listeriolysin O Membrane Damaging Activity Involves Arc Formation and Lineaction -- Implication for Listeria monocytogenes Escape from Phagocytic Vacuole

(2016) Yi Ruan et al.   PLoS Pathogens

Failed CTL/NK cell killing and cytokine hypersecretion are directly linked through prolonged synapse time

(2015) Misty R. Jenkins et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Directly Observing the Lipid-Dependent Self-Assembly and Pore-Forming Mechanism of the Cytolytic Toxin Listeriolysin O

(2015) Estefania Mulvihill et al.   NANO LETTERS

Plasticity of Listeriolysin O Pores and its Regulation by pH and Unique Histidine

(2015) Marjetka Podobnik et al.   Scientific Reports

Conformational Changes during Pore Formation by the Perforin-Related Protein Pleurotolysin

(2015) Natalya Lukoyanova et al.   PLOS BIOLOGY

Perforin oligomers form arcs in cellular membranes: a locus for intracellular delivery of granzymes

(2014) S S Metkar et al.   CELL DEATH AND DIFFERENTIATION

Incomplete pneumolysin oligomers form membrane pores

(2014) A. F.- P. Sonnen et al.   Open Biology

Stepwise visualization of membrane pore formation by suilysin, a bacterial cholesterol-dependent cytolysin

(2014) Carl Leung et al.   eLife

Defining the interaction of perforin with calcium and the phospholipid membrane

(2013) Daouda A. K. Traore et al.   BIOCHEMICAL JOURNAL

Perforin forms transient pores on the target cell plasma membrane to facilitate rapid access of granzymes during killer cell attack

(2013) J. A. Lopez et al.   BLOOD

Effects of MACPF/CDC proteins on lipid membranes

(2012) Robert J. C. Gilbert et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Critical point fluctuations in supported lipid membranes

(2012) Simon D. Connell et al.   FARADAY DISCUSSIONS

Structure of Complement C6 Suggests a Mechanism for Initiation and Unidirectional, Sequential Assembly of Membrane Attack Complex (MAC)

(2012) Alexander E. Aleshin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Monomer-Monomer Interactions Propagate Structural Transitions Necessary for Pore Formation by the Cholesterol-dependent Cytolysins

(2012) Eileen M. Hotze et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

pH dependence of listeriolysin O aggregation and pore-forming ability

(2011) Andrej Bavdek et al.   FEBS Journal

Protection from Endogenous Perforin: Glycans and the C Terminus Regulate Exocytic Trafficking in Cytotoxic Lymphocytes

(2011) Amelia J. Brennan et al.   IMMUNITY

Human Perforin Employs Different Avenues to Damage Membranes

(2010) Tilen Praper et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The structural basis for membrane binding and pore formation by lymphocyte perforin

(2010) Ruby H. P. Law et al.   NATURE