Mechanotransduction-modulated fibrotic microniches reveal the contribution of angiogenesis in liver fibrosis

Biophysical Regulation of Cell Behavior—Cross Talk between Substrate Stiffness and Nanotopography

(2017) Yong Yang et al.   Engineering

Substrate stiffness orchestrates epithelial cellular heterogeneity with controlled proliferative pattern via E-cadherin/β-catenin mechanotransduction

(2016) Bingjie Wang et al.   Acta Biomaterialia

Mechanosensitive subcellular rheostasis drives emergent single-cell mechanical homeostasis

(2016) Shinuo Weng et al.   NATURE MATERIALS

Injectable microcryogels reinforced alginate encapsulation of mesenchymal stromal cells for leak-proof delivery and alleviation of canine disc degeneration

(2015) Yang Zeng et al.   BIOMATERIALS

The role of extracellular matrix in retinal vascular development and preretinal neovascularization

(2015) Paul N. Bishop   EXPERIMENTAL EYE RESEARCH

Resolution of liver fibrosis requires myeloid cell-driven sinusoidal angiogenesis

(2015) Chahrazade Kantari-Mimoun et al.   HEPATOLOGY

Liver sinusoidal endothelial cells in hepatic fibrosis

(2015) Laurie D. DeLeve   HEPATOLOGY

Chronic passive venous congestion drives hepatic fibrogenesis via sinusoidal thrombosis and mechanical forces

(2015) Douglas A. Simonetto et al.   HEPATOLOGY

ZO-1 controls endothelial adherens junctions, cell–cell tension, angiogenesis, and barrier formation

(2015) Olga Tornavaca et al.   JOURNAL OF CELL BIOLOGY

Bi-content micro-collagen chip provides contractility-based biomechanical readout for phenotypic drug screening with expanded and profiled targets

(2015) Hui Zhao et al.   LAB ON A CHIP

High-yield and high-purity isolation of hepatic stellate cells from normal and fibrotic mouse livers

(2015) Ingmar Mederacke et al.   Nature Protocols

Vascular Endothelial Growth Factor Promotes Fibrosis Resolution and Repair in Mice

(2014) Liu Yang et al.   GASTROENTEROLOGY

CCL2-dependent infiltrating macrophages promote angiogenesis in progressive liver fibrosis

(2014) Josef Ehling et al.   GUT

Mechanotransduction and fibrosis

(2014) Dominik Duscher et al.   JOURNAL OF BIOMECHANICS

Discoidin Domain Receptor 2 Signaling Networks and Therapy in Lung Cancer

(2014) Leo S. Payne et al.   Journal of Thoracic Oncology

Extracellular matrix stiffness and composition jointly regulate the induction of malignant phenotypes in mammary epithelium

(2014) Ovijit Chaudhuri et al.   NATURE MATERIALS

Influence of the PDMS substrate stiffness on the adhesion ofAcanthamoeba castellanii

(2014) Sören B Gutekunst et al.   Beilstein Journal of Nanotechnology

Akt1 Mediates α-Smooth Muscle Actin Expression and Myofibroblast Differentiation via Myocardin and Serum Response Factor

(2013) Maha Abdalla et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Therapy for Fibrotic Diseases: Nearing the Starting Line

(2013) S. L. Friedman et al.   Science Translational Medicine

Review article: the reversibility of cirrhosis

(2012) A. A. Sohrabpour et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Angiogenesis in Pulmonary Fibrosis

(2012) Chandru Hanumegowda et al.   CHEST

Angiogenesis and scar formation in healing wounds

(2012) Luisa A. DiPietro   CURRENT OPINION IN RHEUMATOLOGY

Role of Differentiation of Liver Sinusoidal Endothelial Cells in Progression and Regression of Hepatic Fibrosis in Rats

(2011) Guanhua Xie et al.   GASTROENTEROLOGY

Age-Related Intimal Stiffening Enhances Endothelial Permeability and Leukocyte Transmigration

(2011) J. Huynh et al.   Science Translational Medicine

Focal adhesion kinase and its signaling pathways in cell migration and angiogenesis

(2010) Xiaofeng Zhao et al.   ADVANCED DRUG DELIVERY REVIEWS

Intrahepatic angiogenesis and sinusoidal remodeling in chronic liver disease: New targets for the treatment of portal hypertension?

(2010) Dominique Thabut et al.   JOURNAL OF HEPATOLOGY

Allosteric inhibition of lysyl oxidase–like-2 impedes the development of a pathologic microenvironment

(2010) Vivian Barry-Hamilton et al.   NATURE MEDICINE

DEGseq: an R package for identifying differentially expressed genes from RNA-seq data

(2009) Likun Wang et al.   BIOINFORMATICS

Pharmacological inhibition of integrin αvβ3 aggravates experimental liver fibrosis and suppresses hepatic angiogenesis

(2009) Eleonora Patsenker et al.   HEPATOLOGY

Now there are many (stages) where before there was one: In search of a pathophysiological classification of cirrhosis

(2009) Guadalupe Garcia-Tsao et al.   HEPATOLOGY

Human DAZL, DAZ and BOULE genes modulate primordial germ-cell and haploid gamete formation

(2009) Kehkooi Kee et al.   NATURE

Biomechanical regulation of blood vessel growth during tissue vascularization

(2009) Witold W Kilarski et al.   NATURE MEDICINE

Senescence of Activated Stellate Cells Limits Liver Fibrosis

(2008) Valery Krizhanovsky et al.   CELL

Vascular endothelial growth factor and angiopoietin-2 play a major role in the pathogenesis of vascular leakage in cirrhotic rats

(2008) P Melgar-Lesmes et al.   GUT

Beneficial effects of sorafenib on splanchnic, intrahepatic, and portocollateral circulations in portal hypertensive and cirrhotic rats

(2008) Marc Mejias et al.   HEPATOLOGY

The actin cytoskeleton in endothelial cell phenotypes

(2008) Nutan Prasain et al.   MICROVASCULAR RESEARCH

Noninvasive high-resolution in vivo imaging of cell biology in the anterior chamber of the mouse eye

(2008) Stephan Speier et al.   Nature Protocols

Determination of hierarchical relationship of Src and Rac at subcellular locations with FRET biosensors

(2008) M. Ouyang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Attenuation of hepatic fibrosis through captopril and enalapril in the livers of bile duct ligated rats

(2007) Golnar Karimian et al.   BIOMEDICINE & PHARMACOTHERAPY

Cellular and molecular mechanisms of fibrosis

(2007) TA Wynn   JOURNAL OF PATHOLOGY