Bi-content micro-collagen chip provides contractility-based biomechanical readout for phenotypic drug screening with expanded and profiled targets

A ready-to-use, versatile, multiplex-able three-dimensional scaffold-based immunoassay chip for high throughput hepatotoxicity evaluation

(2015) Xiaojun Yan et al.   LAB ON A CHIP

Facile and Rapid Generation of Large-Scale Microcollagen Gel Array for Long-Term Single-Cell 3D Culture and Cell Proliferation Heterogeneity Analysis

(2014) Zhichao Guan et al.   ANALYTICAL CHEMISTRY

Force-driven evolution of mesoscale structure in engineered 3D microtissues and the modulation of tissue stiffening

(2014) Ruogang Zhao et al.   BIOMATERIALS

Magnetically controllable 3D microtissues based on magnetic microcryogels

(2014) Wei Liu et al.   LAB ON A CHIP

Mobile phones democratize and cultivate next-generation imaging, diagnostics and measurement tools

(2014) Aydogan Ozcan   LAB ON A CHIP

Phenotypic screening in cancer drug discovery — past, present and future

(2014) John G. Moffat et al.   NATURE REVIEWS DRUG DISCOVERY

Miniaturized Three-Dimensional Cancer Model for Drug Evaluation

(2013) Carrie J. Lovitt et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

Aqueous two-phase printing of cell-containing contractile collagen microgels

(2013) Christopher Moraes et al.   BIOMATERIALS

Phenotypic screens as a renewed approach for drug discovery

(2013) Wei Zheng et al.   DRUG DISCOVERY TODAY

Micro-scaffold array chip for upgrading cell-based high-throughput drug testing to 3D using benchtop equipment

(2013) Xiaokang Li et al.   LAB ON A CHIP

Hypoxia-inducible factors mediate coordinated RhoA-ROCK1 expression and signaling in breast cancer cells

(2013) D. M. Gilkes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Berberine attenuates bleomycin induced pulmonary toxicity and fibrosis via suppressing NF-κB dependant TGF-β activation: A biphasic experimental study

(2013) Palanivel Chitra et al.   TOXICOLOGY LETTERS

TGF-β1 enhances contractility in engineered skeletal muscle

(2012) Michael R. Weist et al.   Journal of Tissue Engineering and Regenerative Medicine

Multiple Applications of Alamar Blue as an Indicator of Metabolic Function and Cellular Health in Cell Viability Bioassays

(2012) Sephra N. Rampersad   SENSORS

Simvastatin disrupts cytoskeleton and decreases cardiac fibroblast adhesion, migration and viability

(2012) Miguel Copaja et al.   TOXICOLOGY

Modulatory profiling identifies mechanisms of small molecule-induced cell death

(2011) A. J. Wolpaw et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Microfabricated Platform to Measure and Manipulate the Mechanics of Engineered Cardiac Microtissues

(2011) Thomas Boudou et al.   TISSUE ENGINEERING PART A

Biomechanical regulation of contractility: spatial control and dynamics

(2011) Romain Levayer et al.   TRENDS IN CELL BIOLOGY

A distinctive role for focal adhesion proteins in three-dimensional cell motility

(2010) Stephanie I. Fraley et al.   NATURE CELL BIOLOGY

Cell adhesion: integrating cytoskeletal dynamics and cellular tension

(2010) J. Thomas Parsons et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Lipophilic Pyridinium Bisphosphonates: Potent γδT Cell Stimulators

(2009) Yonghui Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Hyaluronic acid-based hydrogels as 3D matrices for in vitro evaluation of chemotherapeutic drugs using poorly adherent prostate cancer cells

(2009) Lisa A. Gurski et al.   BIOMATERIALS

Spheroid-based drug screen: considerations and practical approach

(2009) Juergen Friedrich et al.   Nature Protocols

PROTECTION BY AND ANTI-OXIDANT MECHANISM OF BERBERINE AGAINST RAT LIVER FIBROSIS INDUCED BY MULTIPLE HEPATOTOXIC FACTORS

(2007) Ben-Jian Zhang et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY