Tension stimulation drives tissue formation in scaffold-free systems

Cyclic Equibiaxial Tensile Strain Alters Gene Expression of Chondrocytes via Histone Deacetylase 4 Shuttling

(2016) Chongwei Chen et al.   PLoS One

Human breast cancer invasion and aggression correlates with ECM stiffening and immune cell infiltration

(2015) I. Acerbi et al.   Integrative Biology

Harnessing Biomechanics to Develop Cartilage Regeneration Strategies

(2015) Kyriacos A. Athanasiou et al.   JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME

Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013

(2015) Theo Vos et al.   LANCET

TGF-β1, GDF-5, and BMP-2 Stimulation Induces Chondrogenesis in Expanded Human Articular Chondrocytes and Marrow-Derived Stromal Cells

(2015) Meghan K. Murphy et al.   STEM CELLS

Thyroid hormones enhance the biomechanical functionality of scaffold-free neocartilage

(2015) Jennifer K Lee et al.   ARTHRITIS RESEARCH & THERAPY

Promoting increased mechanical properties of tissue engineered neocartilage via the application of hyperosmolarity and 4α-phorbol 12,13-didecanoate (4αPDD)

(2014) Jennifer K. Lee et al.   JOURNAL OF BIOMECHANICS

Repair and tissue engineering techniques for articular cartilage

(2014) Eleftherios A. Makris et al.   Nature Reviews Rheumatology

Developing functional musculoskeletal tissues through hypoxia and lysyl oxidase-induced collagen cross-linking

(2014) Eleftherios A. Makris et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TRPV4-mediated mechanotransduction regulates the metabolic response of chondrocytes to dynamic loading

(2014) C. J. O'Conor et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Combinatorial scaffold morphologies for zonal articular cartilage engineering

(2013) J.A.M. Steele et al.   Acta Biomaterialia

Enhanced Tissue Regeneration Potential of Juvenile Articular Cartilage

(2013) Hui Liu et al.   AMERICAN JOURNAL OF SPORTS MEDICINE

Synthesis rates and binding kinetics of matrix products in engineered cartilage constructs using chondrocyte-seeded agarose gels

(2013) Robert J. Nims et al.   JOURNAL OF BIOMECHANICS

High mesenchymal stem cell seeding densities in hyaluronic acid hydrogels produce engineered cartilage with native tissue properties

(2012) Isaac E. Erickson et al.   Acta Biomaterialia

TRPV4 channel activation improves the tensile properties of self-assembled articular cartilage constructs

(2012) Sriram V. Eleswarapu et al.   Acta Biomaterialia

Mechanisms underlying the synergistic enhancement of self-assembled neocartilage treated with chondroitinase-ABC and TGF-β1

(2012) Donald J. Responte et al.   BIOMATERIALS

Biomechanics-driven chondrogenesis: from embryo to adult

(2012) Donald J. Responte et al.   FASEB JOURNAL

FEBio: Finite Elements for Biomechanics

(2012) Steve A. Maas et al.   JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME

CULTIVATION OF CHONDROCYTES AND MENISCUS CELLS IN THERMO-RESPONSIVE HYDROGELS CONTAINING CHITOSAN AND HYALURONIC ACID UNDER MECHANICAL TENSILE STIMULATION

(2012) JYH-PING CHEN et al.   Journal of Mechanics in Medicine and Biology

Engineering tendon and ligament tissues: present developments towards successful clinical products

(2012) Márcia T. Rodrigues et al.   Journal of Tissue Engineering and Regenerative Medicine

Unlike Bone, Cartilage Regeneration Remains Elusive

(2012) D. J. Huey et al.   SCIENCE

Advanced cell therapies with and without scaffolds

(2011) Birsen Demirbag et al.   Biotechnology Journal

Tensile Properties, Collagen Content, and Crosslinks in Connective Tissues of the Immature Knee Joint

(2011) Sriram V. Eleswarapu et al.   PLoS One

Mechanical Properties of Natural Cartilage and Tissue-Engineered Constructs

(2011) Christopher James Little et al.   TISSUE ENGINEERING PART B-REVIEWS

Lysyl Oxidase-like-2 (LOXL2) Is a Major Isoform in Chondrocytes and Is Critically Required for Differentiation

(2010) Mussadiq Iftikhar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tensile Loading Modulates Bone Marrow Stromal Cell Differentiation and the Development of Engineered Fibrocartilage Constructs

(2010) John T. Connelly et al.   TISSUE ENGINEERING PART A

Functional characterization of TRPV4 as an osmotically sensitive ion channel in porcine articular chondrocytes

(2009) Mimi N. Phan et al.   ARTHRITIS AND RHEUMATISM

Biomechanical, structural, and biochemical indices of degenerative and osteoarthritic deterioration of adult human articular cartilage of the femoral condyle

(2009) M.M. Temple-Wong et al.   OSTEOARTHRITIS AND CARTILAGE

Smad7 Inhibits Chondrocyte Differentiation at Multiple Steps during Endochondral Bone Formation and Down-regulates p38 MAPK Pathways

(2008) Takao Iwai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lysyl Oxidase Binds Transforming Growth Factor-β and Regulates Its Signaling via Amine Oxidase Activity

(2008) Phimon Atsawasuwan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Articular chondrocytes derived from distinct tissue zones differentially respond to in vitro oscillatory tensile loading

(2008) E.J. Vanderploeg et al.   OSTEOARTHRITIS AND CARTILAGE

Systematic assessment of growth factor treatment on biochemical and biomechanical properties of engineered articular cartilage constructs

(2008) B.D. Elder et al.   OSTEOARTHRITIS AND CARTILAGE

Sequential Biochemical and Mechanical Stimulation in the Development of Tissue-Engineered Ligaments

(2008) Jodie E. Moreau et al.   TISSUE ENGINEERING PART A

Functional tissue engineering for tendon repair: A multidisciplinary strategy using mesenchymal stem cells, bioscaffolds, and mechanical stimulation

(2007) David L. Butler et al.   JOURNAL OF ORTHOPAEDIC RESEARCH