Whole-genome sequencing identifies rare genotypes in COMP and CHADL associated with high risk of hip osteoarthritis

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Weighting sequence variants based on their annotation increases power of whole-genome association studies

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Functional characterisation of the osteoarthritis susceptibility locus at chromosome 6q14.1 marked by the polymorphism rs9350591

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Biomarkers for osteoarthritis: Can they be used for risk assessment? A systematic review

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Loss-of-function variants in ABCA7 confer risk of Alzheimer's disease

(2015) Stacy Steinberg et al.   NATURE GENETICS

Large-scale whole-genome sequencing of the Icelandic population

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Genotype to phenotype correlations in cartilage oligomeric matrix protein associated chondrodysplasias

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The Novel Small Leucine-rich Protein Chondroadherin-like (CHADL) Is Expressed in Cartilage and Modulates Chondrocyte Differentiation

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Severe osteoarthritis of the hand associates with common variants within the ALDH1A2 gene and with rare variants at 1p31

(2014) Unnur Styrkarsdottir et al.   NATURE GENETICS

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(2014) Andrew Nickless et al.   NATURE MEDICINE

TheDOT1Lrs12982744 polymorphism is associated with osteoarthritis of the hip with genome-wide statistical significance in males

(2013) Evangelos Evangelou et al.   ANNALS OF THE RHEUMATIC DISEASES

A meta-analysis of genome-wide association studies identifies novel variants associated with osteoarthritis of the hip

(2013) Evangelos Evangelou et al.   ANNALS OF THE RHEUMATIC DISEASES

Advances in osteoarthritis genetics: Table 1

(2013) Kalliope Panoutsopoulou et al.   JOURNAL OF MEDICAL GENETICS

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(2012) Richard F. Loeser et al.   ARTHRITIS AND RHEUMATISM

Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study

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Identification of the pathogenic pathways in osteoarthritic hip cartilage: commonality and discord between hip and knee OA

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A Variant in MCF2L Is Associated with Osteoarthritis

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Gene inactivation and its implications for annotation in the era of personal genomics

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The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

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Association between occupation and knee and hip replacement due to osteoarthritis: a case-control study

(2010) Jonas Franklin et al.   ARTHRITIS RESEARCH & THERAPY

A scaling normalization method for differential expression analysis of RNA-seq data

(2010) Mark D Robinson et al.   GENOME BIOLOGY

Sex-specific effect of Pirin gene on bone mineral density in a cohort of 4000 Chinese

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Sequence variants at the TERT-CLPTM1L locus associate with many cancer types

(2009) Thorunn Rafnar et al.   NATURE GENETICS

Detection of sharing by descent, long-range phasing and haplotype imputation

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