Functional screen of MSI2 interactors identifies an essential role for SYNCRIP in myeloid leukemia stem cells

MLL-AF9– and HOXA9-mediated acute myeloid leukemia stem cell self-renewal requires JMJD1C

(2016) Nan Zhu et al.   JOURNAL OF CLINICAL INVESTIGATION

Image-based detection and targeting of therapy resistance in pancreatic adenocarcinoma

(2016) Raymond G. Fox et al.   NATURE

A Vector with a Single Promoter for In Vitro Transcription and Mammalian Cell Expression of CRISPR gRNAs

(2016) Peter J. Romanienko et al.   PLoS One

MSI2 is required for maintaining activated myelodysplastic syndrome stem cells

(2016) James Taggart et al.   Nature Communications

The RNA-Binding Protein SYNCRIP Is a Component of the Hepatocyte Exosomal Machinery Controlling MicroRNA Sorting

(2016) Laura Santangelo et al.   Cell Reports

Tetraspanin 3 Is Required for the Development and Propagation of Acute Myelogenous Leukemia

(2015) Hyog Young Kwon et al.   Cell Stem Cell

Musashi2 sustains the mixed-lineage leukemia–driven stem cell regulatory program

(2015) Sun-Mi Park et al.   JOURNAL OF CLINICAL INVESTIGATION

Natural product (−)-gossypol inhibits colon cancer cell growth by targeting RNA-binding protein Musashi-1

(2015) Lan Lan et al.   Molecular Oncology

DOT1L inhibits SIRT1-mediated epigenetic silencing to maintain leukemic gene expression in MLL-rearranged leukemia

(2015) Chun-Wei Chen et al.   NATURE MEDICINE

A 1536-Well Fluorescence Polarization Assay to Screen for Modulators of the MUSASHI Family of RNA-Binding Proteins

(2014) Gerard Minuesa et al.   COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING

A Conserved Three-nucleotide Core Motif Defines Musashi RNA Binding Specificity

(2014) N. Ruth Zearfoss et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Musashi-2 controls cell fate, lineage bias, and TGF-β signaling in HSCs

(2014) Sun-Mi Park et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The biology and clinical impact of genetic lesions in myeloid malignancies

(2013) R. C. Lindsley et al.   BLOOD

In Vivo RNAi Screening Identifies a Leukemia-Specific Dependence on Integrin Beta 3 Signaling

(2013) Peter G. Miller et al.   CANCER CELL

Genomic and Epigenomic Landscapes of Adult De Novo Acute Myeloid Leukemia

(2013)   NEW ENGLAND JOURNAL OF MEDICINE

Versatility of RNA-Binding Proteins in Cancer

(2012) Laurence Wurth   COMPARATIVE AND FUNCTIONAL GENOMICS

hnRNP Q Regulates Cdc42-Mediated Neuronal Morphogenesis

(2012) H.-H. Chen et al.   MOLECULAR AND CELLULAR BIOLOGY

Negative regulation of RhoA translation and signaling by hnRNP-Q1 affects cellular morphogenesis

(2012) Lei Xing et al.   MOLECULAR BIOLOGY OF THE CELL

HemaExplorer: a database of mRNA expression profiles in normal and malignant haematopoiesis

(2012) Frederik Otzen Bagger et al.   NUCLEIC ACIDS RESEARCH

Translational medicine: ribosomopathies

(2011) A. Narla et al.   BLOOD

MSI2 protein expression predicts unfavorable outcome in acute myeloid leukemia

(2011) R. J. Byers et al.   BLOOD

RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia

(2011) Johannes Zuber et al.   NATURE

A transgenic mouse model demonstrates a dominant negative effect of a point mutation in the RPS19 gene associated with Diamond-Blackfan anemia

(2010) E. E. Devlin et al.   BLOOD

Twenty-five years of epidemiological recording on myeloid malignancies: data from the specialized registry of hematologic malignancies of Cote d'Or (Burgundy, France)

(2010) M. Maynadie et al.   HAEMATOLOGICA

Regulation of myeloid leukaemia by the cell-fate determinant Musashi

(2010) Takahiro Ito et al.   NATURE

Toolkit for evaluating genes required for proliferation and survival using tetracycline-regulated RNAi

(2010) Johannes Zuber et al.   NATURE BIOTECHNOLOGY

Musashi-2 regulates normal hematopoiesis and promotes aggressive myeloid leukemia

(2010) Michael G Kharas et al.   NATURE MEDICINE

Constitutional hypomorphic telomerase mutations in patients with acute myeloid leukemia

(2009) R. T. Calado et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Control of c-myc mRNA stability by IGF2BP1-associated cytoplasmic RNPs

(2008) D. Weidensdorfer et al.   RNA

RNA-binding proteins in human genetic disease

(2008) Kiven E. Lukong et al.   TRENDS IN GENETICS