MSI2 is required for maintaining activated myelodysplastic syndrome stem cells

Tetraspanin 3 Is Required for the Development and Propagation of Acute Myelogenous Leukemia

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Musashi2 sustains the mixed-lineage leukemia–driven stem cell regulatory program

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Combining gene mutation with gene expression data improves outcome prediction in myelodysplastic syndromes

(2015) Moritz Gerstung et al.   Nature Communications

Musashi-2 controls cell fate, lineage bias, and TGF-β signaling in HSCs

(2014) Sun-Mi Park et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Brief Report: Loss of p15Ink4b Accelerates Development of Myeloid Neoplasms in Nup98-HoxD13 Transgenic Mice

(2014) Rita Humeniuk et al.   STEM CELLS

Prognostic significance of expression levels of stem cell regulators MSI2 and NUMB in acute myeloid leukemia

(2012) Felicitas Thol et al.   ANNALS OF HEMATOLOGY

Knock-in of a FLT3/ITD mutation cooperates with a NUP98-HOXD13 fusion to generate acute myeloid leukemia in a mouse model

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Loss of p53 accelerates the complications of myelodysplastic syndrome in a NUP98-HOXD13-driven mouse model

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Stem and progenitor cells in myelodysplastic syndromes show aberrant stage-specific expansion and harbor genetic and epigenetic alterations

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Distinct expression profiles of MSI2 and NUMB genes in myelodysplastic syndromes and acute myeloid leukemia patients

(2012) João Kleber Novais Pereira et al.   LEUKEMIA RESEARCH

Musashi 2 is a regulator of the HSC compartment identified by a retroviral insertion screen and knockout mice

(2011) L. de Andres-Aguayo et al.   BLOOD

MSI2 protein expression predicts unfavorable outcome in acute myeloid leukemia

(2011) R. J. Byers et al.   BLOOD

Molecular Biology of Myelodysplastic Syndromes

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A flexible R package for nonnegative matrix factorization

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Deregulated gene expression pathways in myelodysplastic syndrome hematopoietic stem cells

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Regulation of myeloid leukaemia by the cell-fate determinant Musashi

(2010) Takahiro Ito et al.   NATURE

Musashi-2 regulates normal hematopoiesis and promotes aggressive myeloid leukemia

(2010) Michael G Kharas et al.   NATURE MEDICINE

Differential expression analysis for sequence count data

(2010) Simon Anders et al.   GENOME BIOLOGY

Mapping identifiers for the integration of genomic datasets with the R/Bioconductor package biomaRt

(2009) Steffen Durinck et al.   Nature Protocols

Myelodysplastic syndromes

(2008) S. D. Nimer   BLOOD

Leukemic transformation in mice expressing a NUP98-HOXD13 transgene is accompanied by spontaneous mutations in Nras, Kras, and Cbl

(2008) C. Slape et al.   BLOOD

Transplantation of a myelodysplastic syndrome by a long-term repopulating hematopoietic cell

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