Designed cell consortia as fragrance-programmable analog-to-digital converters

Precision Tumor Recognition by T Cells With Combinatorial Antigen-Sensing Circuits

(2016) Kole T. Roybal et al.   CELL

Engineering Customized Cell Sensing and Response Behaviors Using Synthetic Notch Receptors

(2016) Leonardo Morsut et al.   CELL

Cellular heterogeneity mediates inherent sensitivity–specificity tradeoff in cancer targeting by synthetic circuits

(2016) Mathieu Morel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synthetic gene network restoring endogenous pituitary–thyroid feedback control in experimental Graves’ disease

(2016) Pratik Saxena et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synthetic recombinase-based state machines in living cells

(2016) N. Roquet et al.   SCIENCE

Synthetic mixed-signal computation in living cells

(2016) Jacob R. Rubens et al.   Nature Communications

Implantable synthetic cytokine converter cells with AND-gate logic treat experimental psoriasis

(2015) Lina Schukur et al.   Science Translational Medicine

A Synthetic Multifunctional Mammalian pH Sensor and CO2 Transgene-Control Device

(2014) David Ausländer et al.   MOLECULAR CELL

Digital switching in a biosensor circuit via programmable timing of gene availability

(2014) Nicolas Lapique et al.   Nature Chemical Biology

A next-generation dual-recombinase system for time- and host-specific targeting of pancreatic cancer

(2014) Nina Schönhuber et al.   NATURE MEDICINE

Targeting cells with single vectors using multiple-feature Boolean logic

(2014) Lief E Fenno et al.   NATURE METHODS

Principles of genetic circuit design

(2014) Jennifer A N Brophy et al.   NATURE METHODS

Permanent genetic memory with >1-byte capacity

(2014) Lei Yang et al.   NATURE METHODS

Humans Can Discriminate More than 1 Trillion Olfactory Stimuli

(2014) C. Bushdid et al.   SCIENCE

Mind-controlled transgene expression by a wireless-powered optogenetic designer cell implant

(2014) Marc Folcher et al.   Nature Communications

Bile acid-controlled transgene expression in mammalian cells and mice

(2013) Katrin Rössger et al.   METABOLIC ENGINEERING

Synthetic circuits integrating logic and memory in living cells

(2013) Piro Siuti et al.   NATURE BIOTECHNOLOGY

Amplifying Genetic Logic Gates

(2013) J. Bonnet et al.   SCIENCE

Genetic programs constructed from layered logic gates in single cells

(2012) Tae Seok Moon et al.   NATURE

Biomolecular computing systems: principles, progress and potential

(2012) Yaakov Benenson   NATURE REVIEWS GENETICS

Radio-Wave Heating of Iron Oxide Nanoparticles Can Regulate Plasma Glucose in Mice

(2012) S. A. Stanley et al.   SCIENCE

A Synthetic Biology Approach to Understanding Cellular Information Processing

(2012) Katherine A. Riccione et al.   ACS Synthetic Biology

Smart medication through combination of synthetic biology and cell microencapsulation

(2011) Simon Ausländer et al.   METABOLIC ENGINEERING

A new synthesis for antibody-mediated immunity

(2011) Arturo Casadevall et al.   NATURE IMMUNOLOGY

In vivo evidence that retinal bipolar cells generate spikes modulated by light

(2011) Elena Dreosti et al.   NATURE NEUROSCIENCE

The food additive vanillic acid controls transgene expression in mammalian cells and mice

(2011) Marc Gitzinger et al.   NUCLEIC ACIDS RESEARCH

Multiple new site-specific recombinases for use in manipulating animal genomes

(2011) A. Nern et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Synthetic Optogenetic Transcription Device Enhances Blood-Glucose Homeostasis in Mice

(2011) H. Ye et al.   SCIENCE

Multi-Input RNAi-Based Logic Circuit for Identification of Specific Cancer Cells

(2011) Z. Xie et al.   SCIENCE

Expression of a G Protein-coupled Receptor (GPCR) Leads to Attenuation of Signaling by Other GPCRs

(2010) Maria Rosario Tubio et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A designer network coordinating bovine artificial insemination by ovulation-triggered release of implanted sperms

(2010) Christian Kemmer et al.   JOURNAL OF CONTROLLED RELEASE

A tunable dual-promoter integrator for targeting of cancer cells

(2010) Lior Nissim et al.   Molecular Systems Biology

Distributed biological computation with multicellular engineered networks

(2010) Sergi Regot et al.   NATURE

Robust multicellular computing using genetically encoded NOR gates and chemical ‘wires’

(2010) Alvin Tamsir et al.   NATURE

Cis-interactions between Notch and Delta generate mutually exclusive signalling states

(2010) David Sprinzak et al.   NATURE

Self-sufficient control of urate homeostasis in mice by a synthetic circuit

(2010) Christian Kemmer et al.   NATURE BIOTECHNOLOGY

Genetic control of mammalian T-cell proliferation with synthetic RNA regulatory systems

(2010) Y. Y. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A tunable synthetic mammalian oscillator

(2009) Marcel Tigges et al.   NATURE

Controlling transgene expression in subcutaneous implants using a skin lotion containing the apple metabolite phloretin

(2009) M. Gitzinger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synthetic Gene Networks That Count

(2009) A. E. Friedland et al.   SCIENCE