Akt3 is a privileged first responder in isozyme-specific electrophile response

The Die Is Cast: Precision Electrophilic Modifications Contribute to Cellular Decision Making

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On-Demand Targeting: Investigating Biology with Proximity-Directed Chemistry

(2016) Marcus J. C. Long et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

T-REX on-demand redox targeting in live cells

(2016) Saba Parvez et al.   Nature Protocols

A Generalizable Platform for Interrogating Target- and Signal-Specific Consequences of Electrophilic Modifications in Redox-Dependent Cell Signaling

(2015) Hong-Yu Lin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Selective, rapid and optically switchable regulation of protein function in live mammalian cells

(2015) Yu-Hsuan Tsai et al.   Nature Chemistry

Cancer-Associated PTEN Mutants Act in a Dominant-Negative Manner to Suppress PTEN Protein Function

(2014) Antonella Papa et al.   CELL

Substoichiometric Hydroxynonenylation of a Single Protein Recapitulates Whole-Cell-Stimulated Antioxidant Response

(2014) Saba Parvez et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A road map to evaluate the proteome-wide selectivity of covalent kinase inhibitors

(2014) Bryan R Lanning et al.   Nature Chemical Biology

Zebrafish sex: a complicated affair

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Temporally Controlled Targeting of 4-Hydroxynonenal to Specific Proteins in Living Cells

(2013) Xinqiang Fang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A chemoproteomic platform to quantitatively map targets of lipid-derived electrophiles

(2013) Chu Wang et al.   NATURE METHODS

Monoubiquitination of nuclear RelA negatively regulates NF-κB activity independent of proteasomal degradation

(2012) Karin Hochrainer et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Somatic Activation of AKT3 Causes Hemispheric Developmental Brain Malformations

(2012) Annapurna Poduri et al.   NEURON

The Evolution of Protein Kinase Inhibitors from Antagonists to Agonists of Cellular Signaling

(2011) Arvin C. Dar et al.   Annual Review of Biochemistry

The Akt kinases: Isoform specificity in metabolism and cancer

(2011) Eva Gonzalez et al.   CELL CYCLE

Formation and Signaling Actions of Electrophilic Lipids

(2011) Francisco J. Schopfer et al.   CHEMICAL REVIEWS

Evaluation of Different Multidimensional LC–MS/MS Pipelines for Isobaric Tags for Relative and Absolute Quantitation (iTRAQ)-Based Proteomic Analysis of Potato Tubers in Response to Cold Storage

(2011) Yong Yang et al.   JOURNAL OF PROTEOME RESEARCH

Imaging protein activity in live embryos using fluorescence resonance energy transfer biosensors

(2011) Elena Kardash et al.   Nature Protocols

Isoform-specific regulation of Akt by PDGF-induced reactive oxygen species

(2011) R. Wani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Systems Analysis of Protein Modification and Cellular Responses Induced by Electrophile Stress

(2010) Aaron T. Jacobs et al.   ACCOUNTS OF CHEMICAL RESEARCH

Spatiotemporal Analysis of Differential Akt Regulation in Plasma Membrane Microdomains

(2008) Xinxin Gao et al.   MOLECULAR BIOLOGY OF THE CELL

Regulation of brain polyunsaturated fatty acid uptake and turnover

(2008) Chuck T. Chen et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS