DrosophilaWASH is required for integrin-mediated cell adhesion, cell motility and lysosomal neutralization

WHAMY is a novel actin polymerase promoting myoblast fusion, macrophage cell motility and sensory organ development inDrosophila

(2015) Klaus Brinkmann et al.   JOURNAL OF CELL SCIENCE

Wash functions downstream of Rho1 GTPase in a subset of Drosophila immune cell developmental migrations

(2015) Jeffrey M. Verboon et al.   MOLECULAR BIOLOGY OF THE CELL

Beclin orthologs: integrative hubs of cell signaling, membrane trafficking, and physiology

(2015) Beth Levine et al.   TRENDS IN CELL BIOLOGY

VPS35 Parkinson mutation impairs autophagy via WASH

(2014) Eszter Zavodszky et al.   CELL CYCLE

RNF2 is recruited by WASH to ubiquitinate AMBRA1 leading to downregulation of autophagy

(2014) Pengyan Xia et al.   CELL RESEARCH

The Drosophila FHOD1-like formin Knittrig acts through Rok to promote stress fiber formation and directed macrophage migration during the cellular immune response

(2014) U. Lammel et al.   DEVELOPMENT

The vacuolar-type H+-ATPase at a glance - more than a proton pump

(2014) M. E. Maxson et al.   JOURNAL OF CELL SCIENCE

Molecular Insights into Rab7-Mediated Endosomal Recruitment of Core Retromer: Deciphering the Role of Vps26 and Vps35

(2014) Amulya Priya et al.   TRAFFIC

Rab Proteins and the Compartmentalization of the Endosomal System

(2014) A. Wandinger-Ness et al.   Cold Spring Harbor Perspectives in Biology

Mutation in VPS35 associated with Parkinson’s disease impairs WASH complex association and inhibits autophagy

(2014) Eszter Zavodszky et al.   Nature Communications

Late endosomal and lysosomal trafficking during integrin-mediated cell migration and invasion

(2013) Elena Rainero et al.   BIOESSAYS

SCAR/WAVE-mediated processing of engulfed apoptotic corpses is essential for effective macrophage migration in Drosophila

(2013) I R Evans et al.   CELL DEATH AND DIFFERENTIATION

Autophagy regulation by nutrient signaling

(2013) Ryan C Russell et al.   CELL RESEARCH

WASH-driven actin polymerization is required for efficient mycobacterial phagosome maturation arrest

(2013) Margot Kolonko et al.   CELLULAR MICROBIOLOGY

Atg6 is required for multiple vesicle trafficking pathways and hematopoiesis in Drosophila

(2013) B. V. Shravage et al.   DEVELOPMENT

WASH inhibits autophagy through suppression of Beclin 1 ubiquitination

(2013) Pengyan Xia et al.   EMBO JOURNAL

Drosophila pupal macrophages – A versatile tool for combined ex vivo and in vivo imaging of actin dynamics at high resolution

(2013) Moritz Sander et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

A dual role for the  PS integrin myospheroid in mediating Drosophila embryonic macrophage migration

(2013) K. Comber et al.   JOURNAL OF CELL SCIENCE

A high resolution view of the fly actin cytoskeleton lacking a functional WAVE complex

(2013) T. ZOBEL et al.   JOURNAL OF MICROSCOPY

WASH is required for lysosomal recycling and efficient autophagic and phagocytic digestion

(2013) Jason S. King et al.   MOLECULAR BIOLOGY OF THE CELL

Retromer-mediated endosomal protein sorting: all WASHed up!

(2013) Matthew N.J. Seaman et al.   TRENDS IN CELL BIOLOGY

Rab9 and retromer regulate retrograde trafficking of luminal protein required for epithelial tube length control

(2013) Bo Dong et al.   Nature Communications

Drosophila integrin adhesion complexes are essential for hemocyte migration in vivo

(2013) C. G. A. Moreira et al.   Biology Open

Beclin1: A role in membrane dynamics and beyond

(2012) Ellen Wirawan et al.   Autophagy

Regulation of integrin trafficking, cell adhesion, and cell migration by WASH and the Arp2/3 complex

(2012) Steve N. Duleh et al.   Cytoskeleton

Developmental expression of Drosophila Wiskott-Aldrich Syndrome family proteins

(2012) Evelyn Rodriguez-Mesa et al.   DEVELOPMENTAL DYNAMICS

WASH Knockout T Cells Demonstrate Defective Receptor Trafficking, Proliferation, and Effector Function

(2012) J. T. Piotrowski et al.   MOLECULAR AND CELLULAR BIOLOGY

Trafficking defects in WASH-knockout fibroblasts originate from collapsed endosomal and lysosomal networks

(2012) Timothy S. Gomez et al.   MOLECULAR BIOLOGY OF THE CELL

Actin Polymerization Controls the Organization of WASH Domains at the Surface of Endosomes

(2012) Emmanuel Derivery et al.   PLoS One

Actin polymerization driven by WASH causes V-ATPase retrieval and vesicle neutralization before exocytosis

(2011) Michael Carnell et al.   JOURNAL OF CELL BIOLOGY

The Arp2/3 activator WASH regulates  5 1-integrin-mediated invasive migration

(2011) T. Zech et al.   JOURNAL OF CELL SCIENCE

Atg8: an autophagy-related ubiquitin-like protein family

(2011) Tomer Shpilka et al.   GENOME BIOLOGY

WASH and the Arp2/3 complex regulate endosome shape and trafficking

(2010) Steve N. Duleh et al.   Cytoskeleton

WASP Family Proteins: Their Evolution and Its Physiological Implications

(2010) Douwe M. Veltman et al.   MOLECULAR BIOLOGY OF THE CELL

WASH and WAVE actin regulators of the Wiskott-Aldrich syndrome protein (WASP) family are controlled by analogous structurally related complexes

(2010) D. Jia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Delivery of endocytosed membrane proteins to the lysosome

(2009) Paul R. Pryor et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Drosophila Cip4/Toca-1 Integrates Membrane Trafficking and Actin Dynamics through WASP and SCAR/WAVE

(2009) Robert Fricke et al.   CURRENT BIOLOGY

Wash functions downstream of Rho and links linear and branched actin nucleation factors

(2009) R. Liu et al.   DEVELOPMENT

The Arp2/3 Activator WASH Controls the Fission of Endosomes through a Large Multiprotein Complex

(2009) Emmanuel Derivery et al.   DEVELOPMENTAL CELL

A FAM21-Containing WASH Complex Regulates Retromer-Dependent Sorting

(2009) Timothy S. Gomez et al.   DEVELOPMENTAL CELL

Membrane recruitment of the cargo-selective retromer subcomplex is catalysed by the small GTPase Rab7 and inhibited by the Rab-GAP TBC1D5

(2009) M. N. J. Seaman et al.   JOURNAL OF CELL SCIENCE

The endocytic pathway acts downstream of Oskar in Drosophila germ plasm assembly

(2008) T. Tanaka et al.   DEVELOPMENT

Abi induces ectopic sensory organ formation by stimulating EGFR signaling

(2008) Raiko Stephan et al.   MECHANISMS OF DEVELOPMENT