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Food-grade TiO2 impairs intestinal and systemic immune homeostasis, initiates preneoplastic lesions and promotes aberrant crypt development in the rat colon

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Food-grade titanium dioxide exposure exacerbates tumor formation in colitis associated cancer model

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Molecular responses of alveolar epithelial A549 cells to chronic exposure to titanium dioxide nanoparticles: A proteomic view

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Titanium Dioxide Nanoparticles: a Risk for Human Health?

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Long-term exposure of A549 cells to titanium dioxide nanoparticles induces DNA damage and sensitizes cells towards genotoxic agents

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(2016) Cathy Rompelberg et al.   Nanotoxicology

Risk assessment of titanium dioxide nanoparticles via oral exposure, including toxicokinetic considerations

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Inhalation of titanium dioxide induces endoplasmic reticulum stress-mediated autophagy and inflammation in mice

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Biological effect of food additive titanium dioxide nanoparticles on intestine: anin vitrostudy

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Differentin vitroexposure regimens of murine primary macrophages to silver nanoparticles induce different fates of nanoparticles and different toxicological and functional consequences

(2015) Catherine Aude-Garcia et al.   Nanotoxicology

Pharmaceutical/food grade titanium dioxide particles are absorbed into the bloodstream of human volunteers

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Regulatory aspects of nanotechnology in the agri/feed/food sector in EU and non-EU countries

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Effect of titanium dioxide nanoparticles on the cardiovascular system after oral administration

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Titanium Dioxide Nanoparticles Induce Endoplasmic Reticulum Stress-Mediated Autophagic Cell Death via Mitochondria-Associated Endoplasmic Reticulum Membrane Disruption in Normal Lung Cells

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Nano-hydroxyapatite and Nano-titanium Dioxide Exhibit Different Subcellular Distribution and Apoptotic Profile in Human Oral Epithelium

(2014) Chor Yong Tay et al.   ACS Applied Materials & Interfaces

Less Is More: Long-Term in Vitro Exposure to Low Levels of Silver Nanoparticles Provides New Insights for Nanomaterial Evaluation

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Characterization of Food-Grade Titanium Dioxide: The Presence of Nanosized Particles

(2014) Yu Yang et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Characterization of Titanium Dioxide Nanoparticles in Food Products: Analytical Methods To Define Nanoparticles

(2014) Ruud J. B. Peters et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Long-term exposures to low doses of cobalt nanoparticles induce cell transformation enhanced by oxidative damage

(2014) Balasubramanyam Annangi et al.   Nanotoxicology

Long-term exposures to low doses of titanium dioxide nanoparticles induce cell transformation, but not genotoxic damage in BEAS-2B cells

(2014) Gerard Vales et al.   Nanotoxicology

Titanium dioxide nanoparticle impact and translocation through ex vivo, in vivo and in vitro gut epithelia

(2014) Emilie Brun et al.   Particle and Fibre Toxicology

A Molecular Web: Endoplasmic Reticulum Stress, Inflammation, and Oxidative Stress

(2014) Namrata Chaudhari et al.   Frontiers in Cellular Neuroscience

Critical review of public health regulations of titanium dioxide, a human food additive

(2014) Boris Jovanović   Integrated Environmental Assessment and Management

Potential Impact of Quercetin and Idebenone against Immuno- inflammatory and Oxidative Renal Damage Induced in Rats by Titanium Dioxide Nanoparticles Toxicity

(2013) Nouf M. Al-Rasheed et al.   Journal of Oleo Science

Titanium dioxide nanoparticles: a review of current toxicological data

(2013) Hongbo Shi et al.   Particle and Fibre Toxicology

Distinctive Toxicity of TiO2 Rutile/Anatase Mixed Phase Nanoparticles on Caco-2 Cells

(2012) Kirsten Gerloff et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Titanium Dioxide Nanoparticles in Food and Personal Care Products

(2012) Alex Weir et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Influence of simulated gastrointestinal conditions on particle-induced cytotoxicity and interleukin-8 regulation in differentiated and undifferentiated Caco-2 cells

(2012) Kirsten Gerloff et al.   Nanotoxicology

Characterization and Preliminary Toxicity Assay of Nano-Titanium Dioxide Additive in Sugar-Coated Chewing Gum

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Susceptibility of Young and Adult Rats to the Oral Toxicity of Titanium Dioxide Nanoparticles

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Impeded protein folding and function in active inflammatory bowel disease

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Titanium dioxide nanoparticles exhibit genotoxicity and impair DNA repair activity in A549 cells

(2011) Mary-Line Jugan et al.   Nanotoxicology

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Titanium dioxide in our everyday life; is it safe?

(2011) Matej Skocaj et al.   Radiology and Oncology

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(2011) Eleonore Fröhlich et al.   TOXICOLOGY

Origin and fate of dietary nanoparticles and microparticles in the gastrointestinal tract

(2010) Jonathan J. Powell et al.   JOURNAL OF AUTOIMMUNITY

Ultrasonic dispersion of nanoparticles for environmental, health and safety assessment – issues and recommendations

(2010) Julian S. Taurozzi et al.   Nanotoxicology

Toxicological Aspects of Long-Term Treatment of Keratinocytes with ZnO and TiO2 Nanoparticles

(2010) Petra Kocbek et al.   Small

Nanoscale and Fine Zinc Oxide Particles: Can in Vitro Assays Accurately Forecast Lung Hazards following Inhalation Exposures?

(2009) D. B. Warheit et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Identification of the mechanisms that drive the toxicity of TiO2 particulates: the contribution of physicochemical characteristics

(2009) Helinor J Johnston et al.   Particle and Fibre Toxicology

Versatility of Laser Pyrolysis Applied to the Synthesis of TiO2 Nanoparticles – Application to UV Attenuation

(2008) Bruno Pignon et al.   EUROPEAN JOURNAL OF INORGANIC CHEMISTRY

From endoplasmic-reticulum stress to the inflammatory response

(2008) Kezhong Zhang et al.   NATURE

In vitro investigation of oxide nanoparticle and carbon nanotube toxicity and intracellular accumulation in A549 human pneumocytes

(2008) A. Simon-Deckers et al.   TOXICOLOGY