Engineered biomimetic nanovesicles show intrinsic anti-inflammatory properties for the treatment of inflammatory bowel diseases

Broccoli-Derived Nanoparticle Inhibits Mouse Colitis by Activating Dendritic Cell AMP-Activated Protein Kinase

(2017) Zhongbin Deng et al.   MOLECULAR THERAPY

Biological Identity of Nanoparticles In Vivo : Clinical Implications of the Protein Corona

(2017) Giulio Caracciolo et al.   TRENDS IN BIOTECHNOLOGY

Personalized protein corona on nanoparticles and its clinical implications

(2017) Claudia Corbo et al.   Biomaterials Science

Cell source determines the immunological impact of biomimetic nanoparticles

(2016) Michael Evangelopoulos et al.   BIOMATERIALS

Edible ginger-derived nanoparticles: A novel therapeutic approach for the prevention and treatment of inflammatory bowel disease and colitis-associated cancer

(2016) Mingzhen Zhang et al.   BIOMATERIALS

Biosimilar therapies in inflammatory bowel disease: should we care about patient profile?

(2016) Gionata Fiorino et al.   Expert Review of Clinical Immunology

Chitosan nanoparticles reduce LPS-induced inflammatory reaction via inhibition of NF-κB pathway in Caco-2 cells

(2016) Jue Tu et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Effects of the protein corona on liposome–liposome and liposome–cell interactions

(2016) Ennio Tasciotti et al.   International Journal of Nanomedicine

Cyclosporine A-loaded lipid nanoparticles in inflammatory bowel disease

(2016) Melissa Guada et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

The impact of nanoparticle protein corona on cytotoxicity, immunotoxicity and target drug delivery

(2016) Claudia Corbo et al.   Nanomedicine

Biomimetic proteolipid vesicles for targeting inflamed tissues

(2016) R. Molinaro et al.   NATURE MATERIALS

Exosomes released by granulocytic myeloid-derived suppressor cells attenuate DSS-induced colitis in mice

(2016) Yungang Wang et al.   Oncotarget

Biomimetic carriers mimicking leukocyte plasma membrane to increase tumor vasculature permeability

(2016) R. Palomba et al.   Scientific Reports

Inflammatory Bowel Disease: Pathogenesis, Causative Factors, Issues, Drug Treatment Strategies, and Delivery Approaches

(2015) Deependra Singh et al.   CRITICAL REVIEWS IN THERAPEUTIC DRUG CARRIER SYSTEMS

Proteomic Profiling of a Biomimetic Drug Delivery Platform

(2015) Claudia Corbo et al.   CURRENT DRUG TARGETS

Enabling cytoplasmic delivery and organelle targeting by surface modification of nanocarriers

(2015) Alessandro Parodi et al.   Nanomedicine

Epidemiology and risk factors for IBD

(2015) Ashwin N. Ananthakrishnan   Nature Reviews Gastroenterology & Hepatology

Red Blood Cell Membrane as a Biomimetic Nanocoating for Prolonged Circulation Time and Reduced Accelerated Blood Clearance

(2015) Lang Rao et al.   Small

Clinical Implications of Measuring Drug and Anti-Drug Antibodies by Different Assays When Optimizing Infliximab Treatment Failure in Crohn's Disease: Post Hoc Analysis of a Randomized Controlled Trial

(2014) Casper Steenholdt et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Inflammatory Bowel Disease: Etiology, Pathogenesis and Current Therapy

(2014) Joshua Ko et al.   CURRENT PHARMACEUTICAL DESIGN

pH-sensitive nanoparticles for colonic delivery of curcumin in inflammatory bowel disease

(2014) Ana Beloqui et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Micheliolide, a new sesquiterpene lactone that inhibits intestinal inflammation and colitis-associated cancer

(2014) Emilie Viennois et al.   LABORATORY INVESTIGATION

Macrophages and Dendritic Cells Emerge in the Liver during Intestinal Inflammation and Predispose the Liver to Inflammation

(2014) Yohei Mikami et al.   PLoS One

Clearance of pathological antibodies using biomimetic nanoparticles

(2014) Jonathan A. Copp et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A doxorubicin delivery platform using engineered natural membrane vesicle exosomes for targeted tumor therapy

(2013) Yanhua Tian et al.   BIOMATERIALS

Cell Therapies for IBD: What Works?

(2013) Elena Ricart et al.   CURRENT DRUG TARGETS

Individualised therapy is more cost-effective than dose intensification in patients with Crohn’s disease who lose response to anti-TNF treatment: a randomised, controlled trial

(2013) Casper Steenholdt et al.   GUT

VEGF-A isoform modulation in an preclinical TNBS model of ulcerative colitis: protective effects of a VEGF164b therapy

(2013) Walter E Cromer et al.   Journal of Translational Medicine

Targeted Drug Delivery to Intestinal Macrophages by Bioactive Nanovesicles Released from Grapefruit

(2013) Baomei Wang et al.   MOLECULAR THERAPY

An influenza virus-inspired polymer system for the timed release of siRNA

(2013) Nghia P Truong et al.   Nature Communications

PLGA-based nanoparticles: An overview of biomedical applications

(2012) Fabienne Danhier et al.   JOURNAL OF CONTROLLED RELEASE

Synthetic nanoparticles functionalized with biomimetic leukocyte membranes possess cell-like functions

(2012) Alessandro Parodi et al.   Nature Nanotechnology

The endocannabinoid system in inflammatory bowel diseases: from pathophysiology to therapeutic opportunity

(2012) Mireille Alhouayek et al.   TRENDS IN MOLECULAR MEDICINE

Dextran sulphate sodium increases splenic Gr1+CD11b+ cells which accelerate recovery from colitis following intravenous transplantation

(2011) R. Zhang et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

DSS induced colitis increases portal LPS levels and enhances hepatic inflammation and fibrogenesis in experimental NASH

(2011) Erwin Gäbele et al.   JOURNAL OF HEPATOLOGY

Bio-inspired, bioengineered and biomimetic drug delivery carriers

(2011) Jin-Wook Yoo et al.   NATURE REVIEWS DRUG DISCOVERY

Protein delivery using engineered virus-like particles

(2011) S. J. Kaczmarczyk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of the endothelium in inflammatory bowel diseases

(2011) Walter E Cromer   WORLD JOURNAL OF GASTROENTEROLOGY

Adverse effects of biologics used for treating IBD

(2010) Andreas Stallmach et al.   BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY

African-American inflammatory bowel disease in a Southern U.S. health center

(2010) Hemanth Veluswamy et al.   BMC GASTROENTEROLOGY

The safety and side effects of monoclonal antibodies

(2010) Trevor T. Hansel et al.   NATURE REVIEWS DRUG DISCOVERY

The targeting of surface modified silica nanoparticles to inflamed tissue in experimental colitis

(2008) Brice Moulari et al.   BIOMATERIALS