Gelatin-albumin hybrid nanoparticles as matrix metalloproteinases-degradable delivery systems for breast cancer therapy

Albumin hybrid nanoparticles loaded with tyrosine kinase A inhibitor GNF-5837 for targeted inhibition of breast cancer cell growth and invasion

(2016) Vahid Heravi Shargh et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Antibody-targeted biodegradable nanoparticles for cancer therapy

(2016) Vahid Heravi Shargh et al.   Nanomedicine

Ramentaceone, a Naphthoquinone Derived from Drosera sp., Induces Apoptosis by Suppressing PI3K/Akt Signaling in Breast Cancer Cells

(2016) Anna Kawiak et al.   PLoS One

Matrix metalloproteinase-sensitive size-shrinkable nanoparticles for deep tumor penetration and pH triggered doxorubicin release

(2015) Shaobo Ruan et al.   BIOMATERIALS

Human Pancreatic Cancer Tumors Are Nutrient Poor and Tumor Cells Actively Scavenge Extracellular Protein

(2015) J. J. Kamphorst et al.   CANCER RESEARCH

The Utilization of Extracellular Proteins as Nutrients Is Suppressed by mTORC1

(2015) Wilhelm Palm et al.   CELL

Integrin-mediated active tumor targeting and tumor microenvironment response dendrimer-gelatin nanoparticles for drug delivery and tumor treatment

(2015) Guanlian Hu et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Matrix metalloproteinase triggered size-shrinkable gelatin-gold fabricated nanoparticles for tumor microenvironment sensitive penetration and diagnosis of glioma

(2015) Shaobo Ruan et al.   Nanoscale

Principles of nanoparticle design for overcoming biological barriers to drug delivery

(2015) Elvin Blanco et al.   NATURE BIOTECHNOLOGY

Multistage drug delivery system based on microenvironment-responsive dendrimer–gelatin nanoparticles for deep tumor penetration

(2015) Guanlian Hu et al.   RSC Advances

Unraveling the mysteries of serum albumin—more than just a serum protein

(2014) Angelica M. Merlot et al.   Frontiers in Physiology

nab-Paclitaxel mechanisms of action and delivery

(2013) Denise A. Yardley   JOURNAL OF CONTROLLED RELEASE

Stimuli-responsive nanocarriers for drug delivery

(2013) Simona Mura et al.   NATURE MATERIALS

High throughput kinase inhibitor screens reveal TRB3 and MAPK-ERK/TGF  pathways as fundamental Notch regulators in breast cancer

(2013) J. Izrailit et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HSP47 siRNA conjugated with cationized gelatin microspheres suppresses peritoneal fibrosis in mice

(2012) Yoko Obata et al.   Acta Biomaterialia

Normalization of tumour blood vessels improves the delivery of nanomedicines in a size-dependent manner

(2012) Vikash P. Chauhan et al.   Nature Nanotechnology

Molecular networks that regulate cancer metastasis

(2012) Daniela Spano et al.   SEMINARS IN CANCER BIOLOGY

Liposomal SLA co-incorporated with PO CpG ODNs or PS CpG ODNs induce the same protection against the murine model of leishmaniasis

(2012) Vahid Heravi Shargh et al.   VACCINE

Discovery of GNF-5837, a Selective TRK Inhibitor with Efficacy in Rodent Cancer Tumor Models

(2012) Pam Albaugh et al.   ACS Medicinal Chemistry Letters

Preparation of gelatin hydrogels incorporating low-molecular-weight heparin for anti-fibrotic therapy

(2011) Takashi Saito et al.   Acta Biomaterialia

Pro-nerve Growth Factor Induces Autocrine Stimulation of Breast Cancer Cell Invasion through Tropomyosin-related Kinase A (TrkA) and Sortilin Protein

(2011) Yohann Demont et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

APN/CD13-targeting as a strategy to alter the tumor accumulation of liposomes

(2011) Michael Dunne et al.   JOURNAL OF CONTROLLED RELEASE

Targeted drug delivery to tumors: Myths, reality and possibility

(2011) You Han Bae et al.   JOURNAL OF CONTROLLED RELEASE

Impact of albumin on drug delivery — New applications on the horizon

(2011) Bakheet Elsadek et al.   JOURNAL OF CONTROLLED RELEASE

Albumin-based nanoparticles as potential controlled release drug delivery systems

(2011) Ahmed O. Elzoghby et al.   JOURNAL OF CONTROLLED RELEASE

Drug targeting to tumors: Principles, pitfalls and (pre-) clinical progress

(2011) Twan Lammers et al.   JOURNAL OF CONTROLLED RELEASE

Expression of MUC5AC in Ocular Surface Epithelial Cells Using Cationized Gelatin Nanoparticles

(2011) Giovanni Konat Zorzi et al.   MOLECULAR PHARMACEUTICS

Erratum: The targeted delivery of multicomponent cargos to cancer cells by nanoporous particle-supported lipid bilayers

(2011) Carlee E. Ashley et al.   NATURE MATERIALS

Accumulation of sub-100 nm polymeric micelles in poorly permeable tumours depends on size

(2011) H. Cabral et al.   Nature Nanotechnology

Preventive or late administration of anti-NGF therapy attenuates tumor-induced nerve sprouting, neuroma formation, and cancer pain

(2011) Juan Miguel Jimenez-Andrade et al.   PAIN

Tumor delivery of macromolecular drugs based on the EPR effect

(2010) Vladimir Torchilin   ADVANCED DRUG DELIVERY REVIEWS

Matrix Metalloproteinases: Regulators of the Tumor Microenvironment

(2010) Kai Kessenbrock et al.   CELL

Dynamic interplay between the collagen scaffold and tumor evolution

(2010) Mikala Egeblad et al.   CURRENT OPINION IN CELL BIOLOGY

Nanoparticle albumin-bound (nab™)-paclitaxel: improving efficacy and tolerability by targeted drug delivery in metastatic breast cancer

(2010) Javier Cortes et al.   EJC SUPPLEMENTS

Nerve growth factor promotes breast cancer angiogenesis by activating multiple pathways

(2010) Rodrigue Romon et al.   Molecular Cancer

Ku86 is important for TrkA overexpression-induced breast cancer cell invasion

(2010) Chann Lagadec et al.   Proteomics Clinical Applications

Expression of matrix metalloproteinases (MMPs) in primary human breast cancer and breast cancer cell lines: New findings and review of the literature

(2009) Andrea Köhrmann et al.   BMC CANCER

Trk kinase inhibitors as new treatments for cancer and pain

(2009) Tao Wang et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

TrkA overexpression enhances growth and metastasis of breast cancer cells

(2009) C Lagadec et al.   ONCOGENE

Nanoparticle Albumin - Bound (NAB) Technology is a Promising Method for Anti-Cancer Drug Delivery

(2009) Qiang Fu et al.   Recent Patents on Anti-Cancer Drug Discovery

Active targeting schemes for nanoparticle systems in cancer therapeutics

(2008) James D. Byrne et al.   ADVANCED DRUG DELIVERY REVIEWS

Nerve Growth Factor Is a Potential Therapeutic Target in Breast Cancer

(2008) E. Adriaenssens et al.   CANCER RESEARCH

Nerve growth factor/nuclear factor-κB pathway as a therapeutic target in breast cancer

(2008) Ali Naderi et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Albumin as a drug carrier: Design of prodrugs, drug conjugates and nanoparticles

(2008) Felix Kratz   JOURNAL OF CONTROLLED RELEASE

Factors Affecting the Clearance and Biodistribution of Polymeric Nanoparticles

(2008) Frank Alexis et al.   MOLECULAR PHARMACEUTICS