Urate levels predict survival in amyotrophic lateral sclerosis: Analysis of the expanded Pooled Resource Open-Access ALS clinical trials database

Uric Acid as a CNS Antioxidant

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Oral Inosine Persistently Elevates Plasma antioxidant capacity in Parkinson's disease

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Serum urate at trial entry and ALS progression in EMPOWER

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Gout and the risk of Alzheimer's disease: a population-based, BMI-matched cohort study

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Prognostic Role of Serum Levels of Uric Acid in Amyotrophic Lateral Sclerosis

(2015) Seong-il Oh et al.   Journal of Clinical Neurology

Neuroprotective effects of urate are mediated by augmenting astrocytic glutathione synthesis and release

(2015) Rachit Bakshi et al.   NEUROBIOLOGY OF DISEASE

High frequency of SLC22A12 variants causing renal hypouricemia 1 in the Czech and Slovak Roma population; simple and rapid detection method by allele-specific polymerase chain reaction

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Mendelian randomization of serum urate and parkinson disease progression

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Influence of serum uric acid levels on prognosis and survival in amyotrophic lateral sclerosis: a meta-analysis

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Serum uric acid level is associated with the prevalence but not with survival of amyotrophic lateral sclerosis in a Chinese population

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Crowdsourced analysis of clinical trial data to predict amyotrophic lateral sclerosis progression

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The PRO-ACT database: Design, initial analyses, and predictive features

(2014) N. Atassi et al.   NEUROLOGY

Nrf2 Signaling Contributes to the Neuroprotective Effects of Urate against 6-OHDA Toxicity

(2014) Ning Zhang et al.   PLoS One

Amyotrophic Lateral Sclerosis Outcome Measures and the Role of Albumin and Creatinine

(2014) Adriano Chiò et al.   JAMA Neurology

Inosine to Increase Serum and Cerebrospinal Fluid Urate in Parkinson Disease

(2014) Michael A. Schwarzschild et al.   JAMA Neurology

Novel allelic variants and evidence for a prevalent mutation in URAT1 causing renal hypouricemia: biochemical, genetics and functional analysis

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Clinical perspective on oxidative stress in sporadic amyotrophic lateral sclerosis

(2013) Emanuele D’Amico et al.   FREE RADICAL BIOLOGY AND MEDICINE

Genetic variability related to serum uric acid concentration and risk of Parkinson's disease

(2013) Isabel González-Aramburu et al.   MOVEMENT DISORDERS

Relationships between Disease Progression and Serum Levels of Lipid, Urate, Creatinine and Ferritin in Japanese Patients with Amyotrophic Lateral Sclerosis: A Cross-Sectional Study

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Protection of dopaminergic cells by urate requires its accumulation in astrocytes

(2012) Sara Cipriani et al.   JOURNAL OF NEUROCHEMISTRY

Neuroprotection by urate on 6-OHDA-lesioned rat model of Parkinson's disease: linking to Akt/GSK3β signaling pathway

(2012) Li Gong et al.   JOURNAL OF NEUROCHEMISTRY

Uric acid levels predict survival in men with amyotrophic lateral sclerosis

(2012) Sabrina Paganoni et al.   JOURNAL OF NEUROLOGY

Disrupted and transgenic urate oxidase alter urate and dopaminergic neurodegeneration

(2012) X. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Novel mutations in xanthine dehydrogenase/oxidase cause severe hypouricemia: Biochemical and molecular genetic analysis in two Czech families with xanthinuria type I

(2011) Blanka Stiburkova et al.   CLINICA CHIMICA ACTA

Novel homozygous insertion in SLC2A9 gene caused renal hypouricemia

(2011) Blanka Stiburkova et al.   MOLECULAR GENETICS AND METABOLISM

Body mass index, not dyslipidemia, is an independent predictor of survival in amyotrophic lateral sclerosis

(2011) Sabrina Paganoni et al.   MUSCLE & NERVE

ALS clinical trials: Do enrolled patients accurately represent the ALS population?

(2011) A. Chio et al.   NEUROLOGY

Caffeine and uric acid mediate glutathione synthesis for neuroprotection

(2011) K. Aoyama et al.   NEUROSCIENCE

Protective effects of urate against 6-OHDA-induced cell injury in PC12 cells through antioxidant action

(2011) Ting-Ge Zhu et al.   NEUROSCIENCE LETTERS

Pathogenic GLUT9 Mutations Causing Renal Hypouricemia Type 2 (RHUC2)

(2011) Y. Kawamura et al.   NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS

Urate: a novel biomarker of Parkinson’s disease risk, diagnosis and prognosis

(2010) Sara Cipriani et al.   Biomarkers in Medicine

Phase II trial of CoQ10 for ALS finds insufficient evidence to justify phase III

(2009) Petra Kaufmann et al.   ANNALS OF NEUROLOGY

Urate as a Predictor of the Rate of Clinical Decline in Parkinson Disease

(2009) Alberto Ascherio   ARCHIVES OF NEUROLOGY

Low uric acid levels in serum of patients with ALS: Further evidence for oxidative stress?

(2009) D. Keizman et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Serum Urate as a Predictor of Clinical and Radiographic Progression in Parkinson Disease

(2008) Michael A. Schwarzschild   ARCHIVES OF NEUROLOGY