Degeneration of rapid eye movement sleep circuitry underlies rapid eye movement sleep behavior disorder

Evidence that Neurons of the Sublaterodorsal Tegmental Nucleus Triggering Paradoxical (REM) Sleep Are Glutamatergic

(2017) Olivier Clément et al.   SLEEP

The coeruleus/subcoeruleus complex in idiopathic rapid eye movement sleep behaviour disorder

(2016) Mickael Ehrminger et al.   BRAIN

Neuroscience: A Distributed Neural Network Controls REM Sleep

(2016) John Peever et al.   CURRENT BIOLOGY

A Temporally Controlled Inhibitory Drive Coordinates Twitch Movements during REM Sleep

(2016) Patricia L. Brooks et al.   CURRENT BIOLOGY

Abnormal baseline brain activity in Parkinson's disease with and without REM sleep behavior disorder: A resting-state functional MRI study

(2016) Dan Li et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING

Assessment of α-synuclein in submandibular glands of patients with idiopathic rapid-eye-movement sleep behaviour disorder: a case-control study

(2016) Dolores Vilas et al.   LANCET NEUROLOGY

Peripheral Synucleinopathy in Early Parkinson's Disease: Submandibular Gland Needle Biopsy Findings

(2016) Charles H. Adler et al.   MOVEMENT DISORDERS

Targeting α-synuclein: Therapeutic options

(2016) Benjamin Dehay et al.   MOVEMENT DISORDERS

A new view of “dream enactment” in REM sleep behavior disorder

(2016) Mark S. Blumberg et al.   SLEEP MEDICINE REVIEWS

Calcium imaging of sleep–wake related neuronal activity in the dorsal pons

(2016) Julia Cox et al.   Nature Communications

Structural Brain Alterations Associated with Rapid Eye Movement Sleep Behavior Disorder in Parkinson’s Disease

(2016) Soufiane Boucetta et al.   Scientific Reports

Alpha-synuclein propagation: New insights from animal models

(2015) Benjamin Dehay et al.   MOVEMENT DISORDERS

α-Synuclein strains cause distinct synucleinopathies after local and systemic administration

(2015) W. Peelaerts et al.   NATURE

Pathogenesis of Parkinson disease—the gut–brain axis and environmental factors

(2015) Lisa Klingelhoefer et al.   Nature Reviews Neurology

Optogenetic activation of cholinergic neurons in the PPT or LDT induces REM sleep

(2014) Christa J. Van Dort et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Breakdown in REM sleep circuitry underlies REM sleep behavior disorder

(2014) John Peever et al.   TRENDS IN NEUROSCIENCES

Lewy body extracts from Parkinson disease brains trigger α-synuclein pathology and neurodegeneration in mice and monkeys

(2013) Ariadna Recasens et al.   ANNALS OF NEUROLOGY

The coeruleus/subcoeruleus complex in rapid eye movement sleep behaviour disorders in Parkinson’s disease

(2013) Daniel García-Lorenzo et al.   BRAIN

Neurodegenerative disease status and post-mortem pathology in idiopathic rapid-eye-movement sleep behaviour disorder: an observational cohort study

(2013) Alex Iranzo et al.   LANCET NEUROLOGY

Optogenetic identification of a rapid eye movement sleep modulatory circuit in the hypothalamus

(2013) Sonia Jego et al.   NATURE NEUROSCIENCE

Family history of idiopathic REM behavior disorder: A multicenter case-control study

(2013) Y. Dauvilliers et al.   NEUROLOGY

REM Sleep Behavior Disorder in the Korean Elderly Population: Prevalence and Clinical Characteristics

(2013) Suk-Hoon Kang et al.   SLEEP

How does parkinsonism start? Prodromal parkinsonism motor changes in idiopathic REM sleep behaviour disorder

(2012) R. B. Postuma et al.   BRAIN

5-HT1A Receptor-Responsive Pedunculopontine Tegmental Neurons Suppress REM Sleep and Respiratory Motor Activity

(2012) K. P. Grace et al.   JOURNAL OF NEUROSCIENCE

Identification of the Transmitter and Receptor Mechanisms Responsible for REM Sleep Paralysis

(2012) P. L. Brooks et al.   JOURNAL OF NEUROSCIENCE

Pathological  -Synuclein Transmission Initiates Parkinson-like Neurodegeneration in Nontransgenic Mice

(2012) K. C. Luk et al.   SCIENCE

Probable rapid eye movement sleep behavior disorder increases risk for mild cognitive impairment and Parkinson disease: A population-based study

(2011) Brendon P. Boot et al.   ANNALS OF NEUROLOGY

Impaired GABA and Glycine Transmission Triggers Cardinal Features of Rapid Eye Movement Sleep Behavior Disorder in Mice

(2011) P. L. Brooks et al.   JOURNAL OF NEUROSCIENCE

Brainstem and Spinal Cord Circuitry Regulating REM Sleep and Muscle Atonia

(2011) Martina Krenzer et al.   PLoS One

REM Sleep Behavior Disorder in the Marmoset MPTP Model of Early Parkinson Disease

(2011) Peternella S. Verhave et al.   SLEEP

Secondary ‘‘incidental’’ REM sleep behavior disorder: Do we ever think of it?

(2011) Raffaele Manni et al.   SLEEP MEDICINE

White and gray matter abnormalities in idiopathic rapid eye movement sleep behavior disorder: A diffusion-tensor imaging and voxel-based morphometry study

(2010) Christoph Scherfler et al.   ANNALS OF NEUROLOGY

Basal ganglia control of sleep-wake behavior and cortical activation

(2010) Mei-Hong Qiu et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Behavioral Response and Transmitter Release During Atonia Elicited by Medial Medullary Stimulation

(2010) Yuan-Yang Lai et al.   JOURNAL OF NEUROPHYSIOLOGY

Electroencephalographic slowing heralds mild cognitive impairment in idiopathic REM sleep behavior disorder

(2010) Alex Iranzo et al.   SLEEP MEDICINE

The neuronal network responsible for paradoxical sleep and its dysfunctions causing narcolepsy and rapid eye movement (REM) behavior disorder

(2010) Pierre-Hervé Luppi et al.   SLEEP MEDICINE REVIEWS

Potentially Lethal Behaviors Associated With Rapid Eye Movement Sleep Behavior Disorder: Review of the Literature and Forensic Implications

(2009) Carlos H. Schenck et al.   JOURNAL OF FORENSIC SCIENCES

Medullary Circuitry Regulating Rapid Eye Movement Sleep and Motor Atonia

(2009) R. Vetrivelan et al.   JOURNAL OF NEUROSCIENCE

Nonviolent elaborate behaviors may also occur in REM sleep behavior disorder

(2009) D. Oudiette et al.   NEUROLOGY

Hypocretin-2 Saporin Lesions of the Ventrolateral Periaquaductal Gray (vlPAG) Increase REM Sleep in Hypocretin Knockout Mice

(2009) Satvinder Kaur et al.   PLoS One

Glycinergic and GABAA-Mediated Inhibition of Somatic Motoneurons Does Not Mediate Rapid Eye Movement Sleep Motor Atonia

(2008) P. L. Brooks et al.   JOURNAL OF NEUROSCIENCE

Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation

(2008) Jia-Yi Li et al.   NATURE MEDICINE

Lewy body–like pathology in long-term embryonic nigral transplants in Parkinson's disease

(2008) Jeffrey H Kordower et al.   NATURE MEDICINE

Neurotoxic lesions at the ventral mesopontine junction change sleep time and muscle activity during sleep: An animal model of motor disorders in sleep

(2008) Y.-Y. Lai et al.   NEUROSCIENCE