New perspectives on study designs for evaluating neuroprotection in Parkinson's disease

Challenges in detecting disease modification in Parkinson's disease clinical trials

(2016) Dilan Athauda et al.   PARKINSONISM & RELATED DISORDERS

Magnetic Resonance Imaging Features of the Nigrostriatal System: Biomarkers of Parkinson’s Disease Stages?

(2016) Lucie Hopes et al.   PLoS One

Magnetic resonance imaging as a potential biomarker for Parkinson's disease

(2016) Paul Tuite   Translational Research

Rational drug discovery design approaches for treating Parkinson’s disease

(2015) Cornelis J Van der Schyf   Expert Opinion on Drug Discovery

A double-blind, placebo-controlled, randomized withdrawal study of lurasidone for the maintenance of efficacy in patients with schizophrenia

(2015) Rajiv Tandon et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Adjunctive Maintenance Lamotrigine for Pediatric Bipolar I Disorder: A Placebo-Controlled, Randomized Withdrawal Study

(2015) Robert L. Findling et al.   JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY

Motor and Cognitive Advantages Persist 12 Months After Exenatide Exposure in Parkinson’s Disease

(2015) Iciar Aviles-Olmos et al.   Journal of Parkinsons Disease

Network modulation following sham surgery in Parkinson’s disease

(2014) Ji Hyun Ko et al.   JOURNAL OF CLINICAL INVESTIGATION

Targeting Chelatable Iron as a Therapeutic Modality in Parkinson's Disease

(2013) David Devos et al.   ANTIOXIDANTS & REDOX SIGNALING

Trial designs used to study neuroprotective therapy in Parkinson's disease

(2012) Anthony E. Lang et al.   MOVEMENT DISORDERS

Multi-organ autonomic dysfunction in Parkinson disease

(2010) Samay Jain   PARKINSONISM & RELATED DISORDERS

"Disease-modification" trials in Parkinson disease: Target populations, endpoints and study design

(2009) O. Rascol   NEUROLOGY

A Double-Blind, Delayed-Start Trial of Rasagiline in Parkinson's Disease

(2009) C. Warren Olanow et al.   NEW ENGLAND JOURNAL OF MEDICINE

Neuroprotection and imaging studies in Parkinson's disease

(2009) Nicola Pavese et al.   PARKINSONISM & RELATED DISORDERS

A randomized, double-blind, placebo-controlled, delayed start study to assess rasagiline as a disease modifying therapy in Parkinson's disease (the ADAGIO study): Rationale, design, and baseline characteristics

(2008) C. Warren Olanow et al.   MOVEMENT DISORDERS