Hepatoprotective Effect of Carboxymethyl Pachyman in Fluorouracil-Treated CT26-Bearing Mice

Activation of the MAPK/Akt/Nrf2-Egr1/HO-1-GCLc axis protects MG-63 osteosarcoma cells against 15d-PGJ2-mediated cell death

(2016) Chintan N. Koyani et al.   BIOCHEMICAL PHARMACOLOGY

Repeated cycles of 5-fluorouracil chemotherapy impaired anti-tumor functions of cytotoxic T cells in a CT26 tumor-bearing mouse model

(2016) Yanhong Wu et al.   BMC IMMUNOLOGY

Evaluation of optimum conditions for pachyman encapsulated in poly(D,L-lactic acid) nanospheres by response surface methodology and results of a related in vitro study

(2016) Deyun Wang et al.   International Journal of Nanomedicine

Poly(butylcyanoacrylate) and Poly(ε-caprolactone) Nanoparticles Loaded with 5-Fluorouracil Increase the Cytotoxic Effect of the Drug in Experimental Colon Cancer

(2015) Raúl Ortiz et al.   AAPS Journal

Activation of the Nrf2 response by intrinsic hepatotoxic drugs correlates with suppression of NF-κB activation and sensitizes toward TNFα-induced cytotoxicity

(2015) Bram Herpers et al.   ARCHIVES OF TOXICOLOGY

Dissecting molecular cross-talk between Nrf2 and NF-κB response pathways

(2015) Joanna D. Wardyn et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Antiinflammatory and Analgesic Activities of Ethanol Extract and Isolated Compounds from Millettia pulchra

(2015) Xiaowei Huo et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Brazilian green propolis water extract up-regulates the early expression level of HO-1 and accelerates Nrf2 after UVA irradiation

(2015) Yuichi Saito et al.   BMC Complementary and Alternative Medicine

Shenling Baizhu San supresses colitis associated colorectal cancer through inhibition of epithelial-mesenchymal transition and myeloid-derived suppressor infiltration

(2015) Xiaochang Lin et al.   BMC Complementary and Alternative Medicine

Pachymic acid induces apoptosis via activating ROS-dependent JNK and ER stress pathways in lung cancer cells

(2015) Jun Ma et al.   Cancer Cell International

Resveratrol effectively attenuates α-naphthyl-isothiocyanate-induced acute cholestasis and liver injury through choleretic and anti-inflammatory mechanisms

(2014) Tao Wang et al.   ACTA PHARMACOLOGICA SINICA

Hepatoprotective Effect Of Cymbopogon Citratus Aqueous Extract Against Hydrogen Peroxide-Induced Liver Injury In Male Rats

(2014) SM Rahim et al.   African Journal of Traditional Complementary and Alternative Medicines

Nuclear adenomatous polyposis coli suppresses colitis-associated tumorigenesis in mice

(2014) Maged Zeineldin et al.   CARCINOGENESIS

Vitamin D analogs enhance the anticancer activity of 5-fluorouracil in an in vivomouse colon cancer model

(2013) Magdalena Milczarek et al.   BMC CANCER

Teng-Long-Bu-Zhong-Tang, a Chinese herbal formula, enhances anticancer effects of 5 - Fluorouracil in CT26 colon carcinoma

(2013) Shan Deng et al.   BMC Complementary and Alternative Medicine

Antitumor and immunomodulatory activity of a water-soluble low molecular weight polysaccharide from Schisandra chinensis (Turcz.) Baill

(2013) Ting Zhao et al.   FOOD AND CHEMICAL TOXICOLOGY

Enhanced antitumor and reduced toxicity effect of Schisanreae polysaccharide in 5-Fu treated Heps-bearing mice

(2013) Ting Zhao et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Ultra Performance Liquid Chromatography-Based Metabonomic Study of Therapeutic Effect of the Surface Layer of Poria cocos on Adenine-Induced Chronic Kidney Disease Provides New Insight into Anti-Fibrosis Mechanism

(2013) Ying-Yong Zhao et al.   PLoS One

The Keap1-Nrf2 pathway: Mechanisms of activation and dysregulation in cancer

(2013) Emilia Kansanen et al.   Redox Biology

Hepatocyte-specific ablation of spermine/spermidine-N1-acetyltransferase gene reduces the severity of CCl4-induced acute liver injury

(2012) Kamyar Zahedi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Glycerol-Induced Renal Damage Improved by 7-O-Galloyl-D-sedoheptulose Treatment through Attenuating Oxidative Stress

(2012) Chan Hum Park et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Comparison of the anti-inflammatory and analgesic effects of Gentiana macrophylla Pall. and Gentiana straminea Maxim., and identification of their active constituents

(2012) Na Jia et al.   JOURNAL OF ETHNOPHARMACOLOGY

Differential Changes in MAP Kinases, Histone Modifications, and Liver Injury in Rats Acutely Treated With Ethanol

(2010) Annayya R. Aroor et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Anti-Inflammatory and Anti-Apoptotic Roles of Endothelial Cell STAT3 in Alcoholic Liver Injury

(2010) Andrew M. Miller et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Chloroquine potentiates the anti-cancer effect of 5-fluorouracil on colon cancer cells

(2010) Kazuhito Sasaki et al.   BMC CANCER

2,3′,4,4′,5′-Pentamethoxy-trans-stilbene, a resveratrol derivative, inhibits colitis-associated colorectal carcinogenesis in mice

(2010) Haitao Li et al.   BRITISH JOURNAL OF PHARMACOLOGY

Lipid-Based Nanoparticulate Systems for the Delivery of Anti-Cancer Drug Cocktails: Implications on Pharmacokinetics and Drug Toxicities

(2010) Gigi Chiu et al.   CURRENT DRUG METABOLISM

Multiple antimelanoma potential of dry olive leaf extract

(2010) Sanja A. Mijatovic et al.   INTERNATIONAL JOURNAL OF CANCER

The Role of Traditional Chinese Herbal Medicines in Cancer Therapy – from TCM Theory to Mechanistic Insights

(2010) W. Hsiao et al.   PLANTA MEDICA

Rosiglitazone sensitizes hepatocellular carcinoma cell lines to 5-fluorouracil antitumor activity through activation of the PPARγ signaling pathway

(2009) Liang-qi Cao et al.   ACTA PHARMACOLOGICA SINICA

IKK/NF-κB and STAT3 pathways: central signalling hubs in inflammation-mediated tumour promotion and metastasis

(2009) Julia Bollrath et al.   EMBO REPORTS

Regulation of Nrf2-dependent gene expression by 15-deoxy-Δ12,14-prostaglandin J2

(2009) Emilia Kansanen et al.   FREE RADICAL BIOLOGY AND MEDICINE

Cell Type–Dependent Pro- and Anti-Inflammatory Role of Signal Transducer and Activator of Transcription 3 in Alcoholic Liver Injury

(2008) Norio Horiguchi et al.   GASTROENTEROLOGY

Mitogen-Activated Protein (MAP) Kinase/MAP Kinase Phosphatase Regulation: Roles in Cell Growth, Death, and Cancer

(2008) T. Boutros et al.   PHARMACOLOGICAL REVIEWS