Design, Synthesis, and Biological Evaluation of Novel 1,3,4-Thiadiazole Derivatives as Potential Antitumor Agents against Chronic Myelogenous Leukemia: Striking Effect of Nitrothiazole Moiety

Thiadiazole inhibitors: a patent review

(2017) Kamal M. Dawood et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Synthesis, Computational Study, and Evaluation of In Vitro Antimicrobial, Antibiofilm, and Anticancer Activities of New Sulfanyl Aminonaphthoquinone Derivatives

(2017) Nilufer Bayrak et al.   Letters in Drug Design & Discovery

A clue to unprecedented strategy to HIV eradication: “Lock-in and apoptosis”

(2017) Hiroshi Tateishi et al.   Scientific Reports

1,3,4-Thiadiazole Based Anticancer Agents

(2016) Alireza Aliabadi   Anti-Cancer Agents in Medicinal Chemistry

Zinc-mediated binding of a low-molecular-weight stabilizer of the host anti-viral factor apolipoprotein B mRNA-editing enzyme, catalytic polypeptide-like 3G

(2016) Mohamed O. Radwan et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Small-molecule kinase inhibitors: an analysis of FDA-approved drugs

(2016) Peng Wu et al.   DRUG DISCOVERY TODAY

Recent developments of 2-aminothiazoles in medicinal chemistry

(2016) Debasis Das et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and Evaluation of New 1,3,4-Thiadiazole Derivatives as Antinociceptive Agents

(2016) Mehlika Altıntop et al.   MOLECULES

Synthesis andIn VitroEvaluation of New Thiosemicarbazone Derivatives as Potential Antimicrobial Agents

(2016) Zafer Asım Kaplancıklı et al.   Journal of Chemistry

Novel metal chelating molecules with anticancer activity. Striking effect of the imidazole substitution of the histidine–pyridine–histidine system

(2015) Taha F.S. Ali et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis and evaluation of benzosuberone embedded with 1,3,4-oxadiazole, 1,3,4-thiadiazole and 1,2,4-triazole moieties as new potential anti proliferative agents

(2015) Bandi Yadagiri et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Bioactive thiazole and benzothiazole derivatives

(2015) Abdul Rouf et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

A comprehensive review in current developments of benzothiazole-based molecules in medicinal chemistry

(2015) Rangappa S. Keri et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Recent applications of 1,3-thiazole core structure in the identification of new lead compounds and drug discovery

(2015) Adile Ayati et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

1,3,4-Thiadiazoles: A potent multi targeted pharmacological scaffold

(2015) Saqlain Haider et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Targeting cancer with kinase inhibitors

(2015) Stefan Gross et al.   JOURNAL OF CLINICAL INVESTIGATION

Biological and Pharmacological Activities of 1,3,4-Thiadiazole Based Compounds

(2015) Joanna Matysiak   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Synthesis and Evaluation of New Pyrazoline Derivatives as Potential Anticancer Agents

(2015) Muhammed Karabacak et al.   MOLECULES

Recent Patents on Thiazole Derivatives Endowed with Antitumor Activity

(2015) Rita Morigi et al.   Recent Patents on Anti-Cancer Drug Discovery

FDA-approved small-molecule kinase inhibitors

(2015) Peng Wu et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Benzothiazoles: How Relevant in Cancer Drug Design Strategy?

(2014) Meenakshi Singh et al.   Anti-Cancer Agents in Medicinal Chemistry

Synthesis, biological evaluation and molecular modeling of 1,3,4-thiadiazol-2-amide derivatives as novel antitubulin agents

(2014) Yu-Jing Li et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Improved antiproliferative activity of 1,3,4-thiadiazole-containing histone deacetylase (HDAC) inhibitors by introduction of the heteroaromatic surface recognition motif

(2014) Peng Guan et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis and antitumor activities of novel hybrid molecules containing 1,3,4-oxadiazole and 1,3,4-thiadiazole bearing Schiff base moiety

(2014) Kai Zhang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

1,3,4-Thiadiazole: Synthesis, Reactions, and Applications in Medicinal, Agricultural, and Materials Chemistry

(2014) Yang Hu et al.   CHEMICAL REVIEWS

Kinase Drug Discovery – What’s Next in the Field?

(2013) Philip Cohen et al.   ACS Chemical Biology

Discovery of 2-Phenyl-N-(5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl)acetamide Derivatives as Apoptosis Inducers via the Caspase Pathway with Potential Anticancer Activity

(2013) Leila Hosseinzadeh et al.   ARCHIV DER PHARMAZIE

Molecular aspects of cancer cell resistance to chemotherapy

(2013) Magali Rebucci et al.   BIOCHEMICAL PHARMACOLOGY

1,3,4-Thiadiazole and its Derivatives: A Review on Recent Progress in Biological Activities

(2013) Abhishek Kumar Jain et al.   Chemical Biology & Drug Design

Design, synthesis and preliminary bioactivity studies of 1,3,4-thiadiazole hydroxamic acid derivatives as novel histone deacetylase inhibitors

(2012) Peng Guan et al.   BIOORGANIC & MEDICINAL CHEMISTRY

2-Amino-1,3,4-thiadiazole derivative (FABT) inhibits the extracellular signal-regulated kinase pathway and induces cell cycle arrest in human non-small lung carcinoma cells

(2012) M. Juszczak et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Thiadiazole-a Promising Structure in Medicinal Chemistry

(2012) Yijing Li et al.   ChemMedChem

A series of 2-arylamino-5-(indolyl)-1,3,4-thiadiazoles as potent cytotoxic agents

(2012) Dalip Kumar et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Benzothiazoles: Search for anticancer agents

(2012) Malleshappa N. Noolvi et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Medicinal significance of benzothiazole scaffold: an insight view

(2012) Prabodh Chander Sharma et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Synthesis, biological evaluation and molecular docking studies of 1,3,4-thiadiazole derivatives containing 1,4-benzodioxan as potential antitumor agents

(2011) Juan Sun et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis of Some Benzothiazole Based Piperazine-Dithiocarbamate Derivatives and Evaluation of Their Anticancer Activities

(2011) Gulhan Turan-Zitouni et al.   Letters in Drug Design & Discovery

Synthesis of Some Novel Triazole Derivatives and Investigation of Their Antimicrobial Activities

(2011) Mehlika Dilek Altıntop et al.   SYNTHETIC COMMUNICATIONS

Analysis of anticancer drugs: A review

(2011) Susanne Nussbaumer et al.   TALANTA

Biochemical Mechanisms of Resistance to Small-Molecule Protein Kinase Inhibitors

(2010) Ratika Krishnamurty et al.   ACS Chemical Biology

Discovery and SAR of 1,3,4-thiadiazole derivatives as potent Abl tyrosine kinase inhibitors and cytodifferentiating agents

(2007) Marco Radi et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS