Discovery and characterization of novel inhibitors of the sodium-coupled citrate transporter (NaCT or SLC13A5)

Indy knockdown in mice mimics elements of dietary restriction

(2016) Gerald I. Shulman et al.   Aging-US

Selective sodium-dependent glucose transporter 1 inhibitors block glucose absorption and impair glucose-dependent insulinotropic peptide release

(2015) Robert L. Dobbins et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Structure-Based Identification of Inhibitors for the SLC13 Family of Na+/Dicarboxylate Cotransporters

(2015) Claire Colas et al.   BIOCHEMISTRY

Effect of Vildagliptin on Hepatic Steatosis

(2015) Mavin Macauley et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Mutations in SLC13A5 Cause Autosomal-Recessive Epileptic Encephalopathy with Seizure Onset in the First Days of Life

(2014) Julien Thevenon et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Functional characterization of a Na+-dependent dicarboxylate transporter fromVibrio cholerae

(2014) Christopher Mulligan et al.   JOURNAL OF GENERAL PHYSIOLOGY

The Hepatoselective Glucokinase Activator PF-04991532 Ameliorates Hyperglycemia without Causing Hepatic Steatosis in Diabetic Rats

(2014) Derek M. Erion et al.   PLoS One

Sodium-coupled dicarboxylate and citrate transporters from the SLC13 family

(2013) Ana M. Pajor   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

THE ROLE OF INDY IN METABOLIC REGULATION

(2013) Diana M Willmes et al.   Computational and Structural Biotechnology Journal

Mechanistic insights from comparing intrinsic clearance values between human liver microsomes and hepatocytes to guide drug design

(2012) Li Di et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Structure and mechanism of a bacterial sodium-dependent dicarboxylate transporter

(2012) Romina Mancusso et al.   NATURE

Deletion of the Mammalian INDY Homolog Mimics Aspects of Dietary Restriction and Protects against Adiposity and Insulin Resistance in Mice

(2011) Andreas L. Birkenfeld et al.   Cell Metabolism

Development of a new permeability assay using low‐efflux MDCKII cells

(2011) Li Di et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Long-lived Indy and calorie restriction interact to extend life span

(2009) P.-Y. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Discovery of Dapagliflozin: A Potent, Selective Renal Sodium-Dependent Glucose Cotransporter 2 (SGLT2) Inhibitor for the Treatment of Type 2 Diabetes

(2008) Wei Meng et al.   JOURNAL OF MEDICINAL CHEMISTRY

Identification of transport pathways for citric acid cycle intermediates in the human colon carcinoma cell line, Caco-2

(2007) Jittima Weerachayaphorn et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES