Triterpenoids from Ocimum labiatum Activates Latent HIV-1 Expression In Vitro: Potential for Use in Adjuvant Therapy

HIV Latency: Should We Shock or Lock?

(2017) Gilles Darcis et al.   TRENDS IN IMMUNOLOGY

Vorinostat Renders the Replication-Competent Latent Reservoir of Human Immunodeficiency Virus (HIV) Vulnerable to Clearance by CD8 T Cells

(2017) Julia A. Sung et al.   EBioMedicine

Interferon alpha treatment stimulates interferon gamma expression in type I NKT cells and enhances their antiviral effect against hepatitis C virus

(2017) Eisuke Miyaki et al.   PLoS One

HIV-1 latent reservoir: size matters

(2016) Flavia Hodel et al.   Future Virology

Natural Products as Sources of New Drugs from 1981 to 2014

(2016) David J. Newman et al.   JOURNAL OF NATURAL PRODUCTS

Interferon-gamma Inhibits Melanogenesis and Induces Apoptosis in Melanocytes: A Pivotal Role of CD8+ Cytotoxic T Lymphocytes in Vitiligo

(2015) L Yang et al.   ACTA DERMATO-VENEREOLOGICA

Progress and challenges in the use of latent HIV-1 reactivating agents

(2015) Hong-tao Shang et al.   ACTA PHARMACOLOGICA SINICA

Plasma levels of cytokines and chemokines and the risk of mortality in HIV-infected individuals

(2015) Martyn A. French et al.   AIDS

Targeting NF-κB Signaling with Protein Kinase C Agonists As an Emerging Strategy for Combating HIV Latency

(2015) Guochun Jiang et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Antioxidant and anti-inflammatory activity of Ocimum labiatum extract and isolated labdane diterpenoid

(2015) Petrina Kapewangolo et al.   Journal of Inflammation-London

An In-Depth Comparison of Latency-Reversing Agent Combinations in Various In Vitro and Ex Vivo HIV-1 Latency Models Identified Bryostatin-1+JQ1 and Ingenol-B+JQ1 to Potently Reactivate Viral Gene Expression

(2015) Gilles Darcis et al.   PLoS Pathogens

HIV Reactivation from Latency after Treatment Interruption Occurs on Average Every 5-8 Days—Implications for HIV Remission

(2015) Mykola Pinkevych et al.   PLoS Pathogens

In vitroreactivation of latent HIV-1 by cytostatic bis(thiosemicarbazonate) gold(III) complexes

(2014) Pascaline Fonteh et al.   BMC INFECTIOUS DISEASES

Eradicating HIV-1 infection: seeking to clear a persistent pathogen

(2014) Nancie M. Archin et al.   NATURE REVIEWS MICROBIOLOGY

Computer-Guided Design, Synthesis, and Protein Kinase C Affinity of a New Salicylate-Based Class of Bryostatin Analogs

(2014) Paul A. Wender et al.   ORGANIC LETTERS

Histone Deacetylase Inhibitor Romidepsin Induces HIV Expression in CD4 T Cells from Patients on Suppressive Antiretroviral Therapy at Concentrations Achieved by Clinical Dosing

(2014) Datsen George Wei et al.   PLoS Pathogens

HIV/AIDS eradication

(2013) Matthew D. Marsden et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

The Natural Killer Cell Interferon-Gamma Response to Bacteria Is Diminished in Untreated HIV-1 Infection and Defects Persist Despite Viral Suppression

(2013) Stephanie M. Dillon et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Inhibition of HIV-1 enzymes, antioxidant and anti-inflammatory activities of Plectranthus barbatus

(2013) Petrina Kapewangolo et al.   JOURNAL OF ETHNOPHARMACOLOGY

Kleinhospitines A–D, New Cycloartane Triterpenoid Alkaloids from Kleinhovia hospita

(2013) Chang-Xin Zhou et al.   ORGANIC LETTERS

Comparison of HDAC inhibitors in clinical development

(2013) Thomas Aagaard Rasmussen et al.   Human Vaccines & Immunotherapeutics

The Th1/Th2/Th17 cytokine profile of HIV-infected individuals: A multivariate cytokinomics approach

(2012) Aurelia Williams et al.   CYTOKINE

Targeting HIV latency: pharmacologic strategies toward eradication

(2012) Sifei Xing et al.   DRUG DISCOVERY TODAY

Combination of Biological Screening in a Cellular Model of Viral Latency and Virtual Screening Identifies Novel Compounds That Reactivate HIV-1

(2012) E. Gallastegui et al.   JOURNAL OF VIROLOGY

Unknown

(2012) Mudit Tyagi et al.   MOLECULAR MEDICINE

Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy

(2012) N. M. Archin et al.   NATURE

Designed, synthetically accessible bryostatin analogues potently induce activation of latent HIV reservoirs in vitro

(2012) Brian A. DeChristopher et al.   Nature Chemistry

HIV reservoirs and the possibility of a cure for HIV infection

(2011) S. Palmer et al.   JOURNAL OF INTERNAL MEDICINE

Plectranthus: A plant for the future?

(2011) L.J. Rice et al.   SOUTH AFRICAN JOURNAL OF BOTANY

Biomarkers of immune dysfunction in HIV

(2010) Daniel E Nixon et al.   Current Opinion in HIV and AIDS

Multi-analyte profiling of ten cytokines in South African HIV-infected patients with Immune Reconstitution Inflammatory Syndrome (IRIS)

(2010) Catherine M Worsley et al.   AIDS Research and Therapy

Separation and identification of some common isomeric plant triterpenoids by thin-layer chromatography and high-performance liquid chromatography

(2009) Mitja Martelanc et al.   JOURNAL OF CHROMATOGRAPHY A

Anti-HIV-1 protease triterpenoids from Stauntonia obovatifoliola Hayata subsp. intermedia

(2008) Ying Wei et al.   PHYTOCHEMISTRY

Bioactive apocarotenoids from Tectona grandis

(2008) Francisco A. Macías et al.   PHYTOCHEMISTRY