Diabetes Mellitus Accelerates Aβ Pathology in Brain Accompanied by Enhanced GAβ Generation in Nonhuman Primates

GLP-1 Receptor Stimulation Reduces Amyloid-β Peptide Accumulation and Cytotoxicity in Cellular and Animal Models of Alzheimer's Disease

(2017) Yazhou Li et al.   JOURNAL OF ALZHEIMERS DISEASE

Insulin-Resistant Brain State after Intracerebroventricular Streptozotocin Injection Exacerbates Alzheimer-like Changes in Tg2576 AβPP-Overexpressing Mice

(2017) Konstanze Plaschke et al.   JOURNAL OF ALZHEIMERS DISEASE

Inflammation, Defective Insulin Signaling, and Mitochondrial Dysfunction as Common Molecular Denominators Connecting Type 2 Diabetes to Alzheimer Disease

(2014) F. G. De Felice et al.   DIABETES

Impaired amyloid β-degrading enzymes in brain of streptozotocin-induced diabetic rats

(2014) Y. Liu et al.   JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION

Autophagy failure in Alzheimer's disease and the role of defective lysosomal acidification

(2013) Devin M. Wolfe et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Glucose Levels and Risk of Dementia

(2013) Paul K. Crane et al.   NEW ENGLAND JOURNAL OF MEDICINE

Diabetes Alters KIF1A and KIF5B Motor Proteins in the Hippocampus

(2013) Filipa I. Baptista et al.   PLoS One

High Glucose Promotes Aβ Production by Inhibiting APP Degradation

(2013) Yi Yang et al.   PLoS One

Diabetes exacerbates amyloid and neurovascular pathology in aging-accelerated mice

(2012) Antonio Currais et al.   AGING CELL

Accumulation of autophagosomes contributes to enhanced amyloidogenic APP processing under insulin-resistant conditions

(2012) Sung Min Son et al.   Autophagy

Phosphatidylinositol 3-Kinase and Rab5 GTPase Inversely Regulate the Smad Anchor for Receptor Activation (SARA) Protein Independently of Transforming Growth Factor-β1

(2012) Constance E. Runyan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An anti-diabetes agent protects the mouse brain from defective insulin signaling caused by Alzheimer’s disease–associated Aβ oligomers

(2012) Theresa R. Bomfim et al.   JOURNAL OF CLINICAL INVESTIGATION

Brain insulin resistance accelerates Aβ fibrillogenesis by inducing GM1 ganglioside clustering in the presynaptic membranes

(2012) Naoki Yamamoto et al.   JOURNAL OF NEUROCHEMISTRY

Lysosomal Dysfunction in a Mouse Model of Sandhoff Disease Leads to Accumulation of Ganglioside-Bound Amyloid-  Peptide

(2012) S. Keilani et al.   JOURNAL OF NEUROSCIENCE

A Non-transgenic Mouse Model (icv-STZ Mouse) of Alzheimer’s Disease: Similarities to and Differences from the Transgenic Model (3xTg-AD Mouse)

(2012) Yanxing Chen et al.   MOLECULAR NEUROBIOLOGY

Phosphoinositide isoforms determine compartment-specific ion channel activity

(2012) X. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dynein Dysfunction Disrupts Intracellular Vesicle Trafficking Bidirectionally and Perturbs Synaptic Vesicle Docking via Endocytic Disturbances

(2011) Nobuyuki Kimura et al.   AMERICAN JOURNAL OF PATHOLOGY

Risk Factors and Preventive Interventions for Alzheimer Disease

(2011) Martha L. Daviglus   ARCHIVES OF NEUROLOGY

Environmental enrichment ameliorated high-fat diet-induced Aβ deposition and memory deficit in APP transgenic mice

(2011) Masato Maesako et al.   NEUROBIOLOGY OF AGING

Metabolic-cognitive syndrome: A cross-talk between metabolic syndrome and Alzheimer's disease

(2010) Vincenza Frisardi et al.   AGEING RESEARCH REVIEWS

SYMPOSIUM REVIEW: Phosphoinositides: lipid regulators of membrane proteins

(2010) Björn H. Falkenburger et al.   JOURNAL OF PHYSIOLOGY-LONDON

Diabetes-accelerated memory dysfunction via cerebrovascular inflammation and A  deposition in an Alzheimer mouse model with diabetes

(2010) S. Takeda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Alzheimer-type tau pathology in advanced aged nonhuman primate brains harboring substantial amyloid deposition

(2009) Naoto Oikawa et al.   BRAIN RESEARCH

Dynein Dysfunction Induces Endocytic Pathology Accompanied by an Increase in Rab GTPases

(2009) Nobuyuki Kimura et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Late endocytic dysfunction as a putative cause of amyloid fibril formation in Alzheimer’s disease

(2009) Kohei Yuyama et al.   JOURNAL OF NEUROCHEMISTRY

Protection of synapses against Alzheimer's-linked toxins: Insulin signaling prevents the pathogenic binding of Aβ oligomers

(2009) Fernanda G. De Felice et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Autophagy Induction and Autophagosome Clearance in Neurons: Relationship to Autophagic Pathology in Alzheimer's Disease

(2008) B. Boland et al.   JOURNAL OF NEUROSCIENCE

Amyloid beta oligomers induce impairment of neuronal insulin receptors

(2007) Wei-Qin Zhao et al.   FASEB JOURNAL