Maternal betaine supplementation in rats induces intergenerational changes in hepatic IGF-1 expression and DNA methylation

Betaine chemistry, roles, and potential use in liver disease

(2016) Christopher R. Day et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Gestational dietary betaine supplementation suppresses hepatic expression of lipogenic genes in neonatal piglets through epigenetic and glucocorticoid receptor-dependent mechanisms

(2016) Demin Cai et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Glucose metabolism and hepatic Igf1 DNA methylation are altered in the offspring of dams fed a low-salt diet during pregnancy

(2016) Flavia R. Siqueira et al.   PHYSIOLOGY & BEHAVIOR

Maternal Betaine Supplementation during Gestation Enhances Expression of mtDNA-Encoded Genes through D-Loop DNA Hypomethylation in the Skeletal Muscle of Newborn Piglets

(2015) Yimin Jia et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Nongenetic inheritance and transgenerational epigenetics

(2015) Moshe Szyf   TRENDS IN MOLECULAR MEDICINE

Effects of betaine on performance and body composition: a review of recent findings and potential mechanisms

(2014) Jason M. Cholewa et al.   AMINO ACIDS

Maternal dietary betaine supplementation modifies hepatic expression of cholesterol metabolic genes via epigenetic mechanisms in newborn piglets

(2014) Demin Cai et al.   BRITISH JOURNAL OF NUTRITION

Dietary betaine supplementation to gestational sows enhances hippocampal IGF2 expression in newborn piglets with modified DNA methylation of the differentially methylated regions

(2014) Xi Li et al.   EUROPEAN JOURNAL OF NUTRITION

Betaine Supplementation in Maternal Diet Modulates the Epigenetic Regulation of Hepatic Gluconeogenic Genes in Neonatal Piglets

(2014) Demin Cai et al.   PLoS One

F0 maternal BPA exposure induced glucose intolerance of F2 generation through DNA methylation change in Gck

(2014) Gengqi Li et al.   TOXICOLOGY LETTERS

Transgenerational effects of prenatal exposure to the 1944-45 Dutch famine

(2013) MVE Veenendaal et al.   BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY

Betaine supplement enhances skeletal muscle differentiation in murine myoblasts via IGF-1 signaling activation

(2013) Pamela Senesi et al.   Journal of Translational Medicine

Excess of Methyl Donor in the Perinatal Period Reduces Postnatal Leptin Secretion in Rat and Interacts with the Effect of Protein Content in Diet

(2013) Fanny Giudicelli et al.   PLoS One

Betaine supplementation enhances anabolic endocrine and Akt signaling in response to acute bouts of exercise

(2012) Jenna M. Apicella et al.   EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY

A unique regulatory phase of DNA methylation in the early mammalian embryo

(2012) Zachary D. Smith et al.   NATURE

Understanding transgenerational epigenetic inheritance via the gametes in mammals

(2012) Lucia Daxinger et al.   NATURE REVIEWS GENETICS

The next generation of disease risk: Are the effects of prenatal nutrition transmitted across generations? Evidence from animal and human studies

(2012) T.J. Roseboom et al.   PLACENTA

Dietary methyl donor deficiency during pregnancy in rats shapes learning and anxiety in offspring

(2011) Galina Konycheva et al.   NUTRITION RESEARCH

Dietary Protein Restriction during F0 Pregnancy in Rats Induces Transgenerational Changes in the Hepatic Transcriptome in Female Offspring

(2011) Samuel P. Hoile et al.   PLoS One

The clinical significance of betaine, an osmolyte with a key role in methyl group metabolism

(2010) Michael Lever et al.   CLINICAL BIOCHEMISTRY

Epigenetics: intrauterine growth retardation (IUGR) modifies the histone code along the rat hepatic IGF-1 gene

(2009) Qi Fu et al.   FASEB JOURNAL

Protein restriction during gestation and/or lactation causes adverse transgenerational effects on biometry and glucose metabolism in F1 and F2 progenies of rats

(2008) Alessandra R. Pinheiro et al.   CLINICAL SCIENCE

The hormonal action of IGF1 in postnatal mouse growth

(2008) E. Stratikopoulos et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA