Atorvastatin Promotes Cytotoxicity and Reduces Migration and Proliferation of Human A172 Glioma Cells

Atorvastatin Prevents Glutamate Uptake Reduction Induced by Quinolinic Acid Via MAPKs Signaling

(2016) S. Vandresen-Filho et al.   NEUROCHEMICAL RESEARCH

Pitfalls of the MTT assay: Direct and off-target effects of inhibitors can result in over/underestimation of cell viability

(2015) A.A. Stepanenko et al.   GENE

Lovastatin and perillyl alcohol inhibit glioma cell invasion, migration, and proliferation – Impact of Ras-/Rho-prenylation

(2015) Sarah Afshordel et al.   PHARMACOLOGICAL RESEARCH

Dihydroartemisinin increases temozolomide efficacy in glioma cells by inducing autophagy

(2015) ZE-SHUN ZHANG et al.   Oncology Letters

GluN2B N-methyl-D-aspartic acid receptor subunit mediates atorvastatin-Induced neuroprotection after focal cerebral ischemia

(2014) Johanna Andrea Gutierrez-Vargas et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Novel anti-glioblastoma agents and therapeutic combinations identified from a collection of FDA approved drugs

(2014) Pengfei Jiang et al.   Journal of Translational Medicine

Temozolomide induces autophagy via ATM-AMPK-ULK1 pathways in glioma

(2014) YUHUI ZOU et al.   Molecular Medicine Reports

Fluvastatin inhibits growth and alters the malignant phenotype of the C6 glioma cell line

(2014) Adrianna Sławińska-Brych et al.   Pharmacological Reports

Kynurenic acid inhibits proliferation and migration of human glioblastoma T98G cells

(2014) Katarzyna Walczak et al.   Pharmacological Reports

In vitro Cell Migration and Invasion Assays

(2014) Calvin R. Justus et al.   Jove-Journal of Visualized Experiments

FOXO/TXNIP pathway is involved in the suppression of hepatocellular carcinoma growth by glutamate antagonist MK-801

(2013) Fuminori Yamaguchi et al.   BMC CANCER

Cell migration or cytokinesis and proliferation? – Revisiting the “go or grow” hypothesis in cancer cells in vitro

(2013) Tamás Garay et al.   EXPERIMENTAL CELL RESEARCH

Atorvastatin suppresses glioma invasion and migration by reducing microglial MT1-MMP expression

(2013) Yi Yongjun et al.   JOURNAL OF NEUROIMMUNOLOGY

Atorvastatin prevents cell damage via modulation of oxidative stress, glutamate uptake and glutamine synthetase activity in hippocampal slices subjected to oxygen/glucose deprivation

(2013) Samuel Vandresen-Filho et al.   NEUROCHEMISTRY INTERNATIONAL

Synergistic Inhibition of Survival, Proliferation, and Migration of U87 Cells with a Combination of LY341495 and Iressa

(2013) Zarina Yelskaya et al.   PLoS One

Evidence for new targets and synergistic effect of metronomic celecoxib/fluvastatin combination in pilocytic astrocytoma

(2013) Sandy Mercurio et al.   Acta Neuropathologica Communications

Selected statins produce rapid spinal motor neuron loss in vitro

(2012) Beth B Murinson et al.   BMC MUSCULOSKELETAL DISORDERS

Mosaic Analysis with Double Markers Reveals Tumor Cell of Origin in Glioma

(2011) Chong Liu et al.   CELL

Glutamate increases pancreatic cancer cell invasion and migration via AMPA receptor activation and Kras-MAPK signaling

(2011) Alexander Herner et al.   INTERNATIONAL JOURNAL OF CANCER

Statin-induced apoptosis via the suppression of ERK1/2 and Akt activation by inhibition of the geranylgeranyl-pyrophosphate biosynthesis in glioblastoma

(2011) Masashi Yanae et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

The neurobiology of gliomas: from cell biology to the development of therapeutic approaches

(2011) Manfred Westphal et al.   NATURE REVIEWS NEUROSCIENCE

Inhibition of AMPK-dependent autophagy enhances in vitro antiglioma effect of simvastatin

(2011) Maja Misirkic et al.   PHARMACOLOGICAL RESEARCH

Cytotoxic effect of different statins and thiazolidinediones on malignant glioma cells

(2010) Jorge Humberto Tapia-Pérez et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Inhibition of Autophagy Enhances Anticancer Effects of Atorvastatin in Digestive Malignancies

(2010) P.-M. Yang et al.   CANCER RESEARCH

Atorvastatin prevents hippocampal cell death, neuroinflammation and oxidative stress following amyloid-β1–40 administration in mice: Evidence for dissociation between cognitive deficits and neuronal damage

(2010) Tetsadê C.B. Piermartiri et al.   EXPERIMENTAL NEUROLOGY

Glutamate and the biology of gliomas

(2010) John de Groot et al.   GLIA

Chemo-Resistant Protein Expression Pattern of Glioblastoma Cells (A172) to Perillyl Alcohol

(2010) Juliana de Saldanha da Gama Fischer et al.   JOURNAL OF PROTEOME RESEARCH

Breast cancer expresses functional NMDA receptors

(2009) William G. North et al.   BREAST CANCER RESEARCH AND TREATMENT

Genetic alterations and signaling pathways in the evolution of gliomas

(2009) Hiroko Ohgaki et al.   CANCER SCIENCE

Expression of glutamate receptor subunits in human cancers

(2009) Andrzej Stepulak et al.   HISTOCHEMISTRY AND CELL BIOLOGY

EFFECT OF SIMVASTATIN ON GLIOMA CELL PROLIFERATION, MIGRATION, AND APOPTOSIS

(2009) Hongtao Wu et al.   NEUROSURGERY

Atorvastatin Prevents Hippocampal Cell Death due to Quinolinic Acid-Induced Seizures in Mice by Increasing Akt Phosphorylation and Glutamate Uptake

(2009) Tetsadê C. B. Piermartiri et al.   NEUROTOXICITY RESEARCH

Characterization of a Multiple Ligand-Gated Ion Channel Cellular Membrane Affinity Chromatography Column and Identification of Endogenously Expressed Receptors in Astrocytoma Cell Lines

(2008) T. Kitabatake et al.   ANALYTICAL CHEMISTRY

Guanosine promotes B16F10 melanoma cell differentiation through PKC–ERK 1/2 pathway

(2008) Katya Naliwaiko et al.   CHEMICO-BIOLOGICAL INTERACTIONS

High dose of simvastatin induces hyperlocomotive and anxiolytic-like activities: The association with the up-regulation of NMDA receptor binding in the rat brain

(2008) Qing Wang et al.   EXPERIMENTAL NEUROLOGY

Knockdown of GluR1 expression by RNA interference inhibits glioma proliferation

(2008) John F. de Groot et al.   JOURNAL OF NEURO-ONCOLOGY

Thyroid hormone increases astrocytic glutamate uptake and protects astrocytes and neurons against glutamate toxicity

(2008) Cláudia Beatriz Nedel Mendes-de-Aguiar et al.   JOURNAL OF NEUROSCIENCE RESEARCH