Statin-induced apoptosis via the suppression of ERK1/2 and Akt activation by inhibition of the geranylgeranyl-pyrophosphate biosynthesis in glioblastoma

Blockade of the Ras/MEK/ERK and Ras/PI3K/Akt pathways by statins reduces the expression of bFGF, HGF, and TGF-β as angiogenic factors in mouse osteosarcoma

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Fluvastatin and cisplatin demonstrate synergistic cytotoxicity in epithelial ovarian cancer cells

(2010) Barbie Taylor-Harding et al.   GYNECOLOGIC ONCOLOGY

Lovastatin overcomes gefitinib resistance in human non-small cell lung cancer cells with K-Ras mutations

(2009) In Hae Park et al.   INVESTIGATIONAL NEW DRUGS

Statin induced myotoxicity: The lactone forms are more potent than the acid forms in human skeletal muscle cells in vitro

(2008) Ine Blankenberg Skottheim et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

A phase II clinical trial does not show that high dose simvastatin has beneficial effect on markers of bone turnover in multiple myeloma

(2008) TE Sondergaard et al.   HEMATOLOGICAL ONCOLOGY

Fluvastatin Induces Apoptosis on Human Tongue Carcinoma Cell Line HSC-3

(2008) Kimiko FUJIWARA et al.   YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN