Soluble Epoxide Hydrolase Inhibition Attenuates MPTP-Induced Neurotoxicity in the Nigrostriatal Dopaminergic System: Involvement of α-Synuclein Aggregation and ER Stress

Protein aggregation and ER stress

(2016) Navit Ogen-Shtern et al.   BRAIN RESEARCH

An Overview on the Role of α -Synuclein in Experimental Models of Parkinson’s Disease from Pathogenesis to Therapeutics

(2016) Hayate Javed et al.   CNS & Neurological Disorders-Drug Targets

Baicalein attenuates α-synuclein aggregation, inflammasome activation and autophagy in the MPP+-treated nigrostriatal dopaminergic system in vivo

(2016) Kai-Chih Hung et al.   JOURNAL OF ETHNOPHARMACOLOGY

14,15-epoxyeicosatrienoic acid promotes production of brain derived neurotrophic factor from astrocytes and exerts neuroprotective effects during ischaemic injury

(2016) L. Yuan et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Soluble epoxide hydrolase inhibitor 1-trifluoromethoxyphenyl-3- (1-propionylpiperidin-4-yl) urea attenuates bleomycin-induced pulmonary fibrosis in mice

(2015) Yong Zhou et al.   CELL AND TISSUE RESEARCH

Parkinson’s disease and enhanced inflammatory response

(2015) Iva Stojkovska et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Epoxyeicosanoid Signaling Provides Multi-target Protective Effects on Neurovascular Unit in Rats After Focal Ischemia

(2015) Yang Liu et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Soluble epoxide hydrolase inhibition provides multi-target therapeutic effects in rats after spinal cord injury

(2015) Xiaojing Chen et al.   MOLECULAR NEUROBIOLOGY

Soluble Epoxide Hydrolase as an Anti-inflammatory Target of the Thrombolytic Stroke Drug SMTP-7

(2014) Naoki Matsumoto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Soluble Epoxide Hydrolase Deficiency or Inhibition Attenuates MPTP-Induced Parkinsonism

(2014) Xiaocui Qin et al.   MOLECULAR NEUROBIOLOGY

The Protective Effect of Epoxyeicosatrienoic Acids on Cerebral Ischemia/Reperfusion Injury is Associated with PI3K/Akt Pathway and ATP-Sensitive Potassium Channels

(2014) You-Yang Qu et al.   NEUROCHEMICAL RESEARCH

Epoxyeicosatrienoic acids pretreatment improves amyloid β-induced mitochondrial dysfunction in cultured rat hippocampal astrocytes

(2013) Pallabi Sarkar et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

The protective effect of astrocyte-derived 14,15-epoxyeicosatrienoic acid on hydrogen peroxide-induced cell injury in astrocyte-dopaminergic neuronal cell line co-culture

(2012) M. Terashvili et al.   NEUROSCIENCE

Role of Alpha-Synuclein Protein Levels in Mitochondrial Morphology and Cell Survival in Cell Lines

(2012) Min Zhu et al.   PLoS One

Alpha-synuclein: from secretion to dysfunction and death

(2012) O Marques et al.   Cell Death & Disease

Oxidative Stress in Parkinson's Disease

(2010) Chun Zhou et al.   Annals of the New York Academy of Sciences

Metals, oxidative stress and neurodegenerative disorders

(2010) Klaudia Jomova et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Anti-inflammatory effects of pioglitazone on iron-induced oxidative injury in the nigrostriatal dopaminergic system

(2010) H. C. Yu et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Heme oxygenase-1 and neurodegeneration: expanding frontiers of engagement

(2009) Hyman M. Schipper et al.   JOURNAL OF NEUROCHEMISTRY

Distribution of soluble and microsomal epoxide hydrolase in the mouse brain and its contribution to cerebral epoxyeicosatrienoic acid metabolism

(2009) A. Marowsky et al.   NEUROSCIENCE

Distribution and Expression of Soluble Epoxide Hydrolase in Human Brain

(2008) Priyanka Sura et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Microsomal epoxide hydrolase deletion enhances tyrosine hydroxylase phosphorylation in mice after MPTP treatment

(2008) Mei Liu et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Soluble Epoxide Hydrolase Gene Deletion Is Protective Against Experimental Cerebral Ischemia

(2008) Wenri Zhang et al.   STROKE